Correlation between the micromorphological parameters and residual solvent content of a crystalline steroid drug

2006 ◽  
Vol 167 (2) ◽  
pp. 104-107 ◽  
Author(s):  
Magdolna Hasznos-Nezdei ◽  
József Kovács ◽  
Sándor Kováts ◽  
Amir Bashiri Shahroodi ◽  
Piroska Szabó-Révész
Keyword(s):  
Residual Solvent ◽  
Solvent Content ◽  
Steroid Drug

scholarly journals KARAKTERISTIK DAN SKRINING FITOKIMIA EKSTRAK ETANOL 70% BATANG KEPUH (Sterculia foetida L.)

Jurnal Kimia ◽  
2019 ◽  
Vol 13 (1) ◽  
pp. 22
Author(s):  
N. P. S. E. Cahyani ◽  
J. Susiarni ◽  
K. C.S. Dewi ◽  
N. L.P. Melyandari ◽  
K. W.A. Putra ◽  
...  
Keyword(s):  
Moisture Content ◽  
Water Content ◽  
Ethanol Extract ◽  
Phytochemical Screening ◽  
Residual Solvent ◽  
Solvent Content ◽  
Residual Content ◽  
Ethanol Level ◽  
Anti Inflammatory

Kepuh (Sterculia foetida L) is a type of kapok plant that has been scientifically proven to have activity as an anti-inflammatory and analgesic. 70% ethanol extract of stem stem is obtained by maceration using 70% ethanol. Examination of the characteristics of 70% ethanol extract of kepuh stem included organoleptic, of moisture content and determination of residual solvent content. Phytochemical screening of 70% ethanol extract of kepuh bark includes: alkaloid, flavonoid, saponin, tannin , polyphenol, and examination of glycosides. The results of the examination of the characteristics of 70% ethanol extract of kepuh stem obtained water content of 8.66 ± 0.748%, the residual content of the solvent had a 0 (zero) ethanol level. The results of phytochemical screening showed 70% ethanol extract of stem stem containing steroid compounds, triterpenoids, flavonoids, saponins, tannins and polyphenols. The identification using UV-Vis spectrophotometry produced ? 212, the absorbance was 1.8601 and ? 284, the absorbance was 0.42186.

scholarly journals ANTHOCYANIN EXTRACTION OF RED DRAGON FRUIT PEELS (Hylocereus polyrhizus) USING MACERATION METHOD

2021 ◽  
Vol 11 (2) ◽  
pp. 72-81
Author(s):  
Asri - Widyasanti ◽  
Muhammad Ziauddin Arsyad ◽  
Endah Wulandari
Keyword(s):  
Total Yield ◽  
Anthocyanin Content ◽  
Solvent Ratio ◽  
Fruit Peel ◽  
Total Anthocyanin ◽  
Residual Solvent ◽  
Solvent Content ◽  
Total Anthocyanin Content ◽  
Dragon Fruit ◽  
Hylocereus Polyrhizus

Anthocyanins present in the red dragon fruit peel (Hylocereus polyrhizus) can be used as natural dyes. An extraction procedure can be used to acquire anthocyanins. The maceration method was used to isolate anthocyanin dyes in this analysis. The aim of this study was to see how the solvent ratio affected the total anthocyanin content in the skin of red dragon fruit. This research used laboratory experimental method using descriptive analysis. The solvent ratios used were (1:30, 1:40, 1:50 and 1:60) with a mixture of distilled water with 10% citric acid as the solvent. Parameters observed were total yield, pH, residual solvent content, spesific gravity and total anthocyanin content.  The best treatment was found to be red dragon fruit peel with a solvent ratio of 1:30, which produced the highest total anthocyanin content of 4.73 mg/L. This treatment resulted total yield 7.40%, residual solvent content 0.05%, spesific gravity 1.30, and pH 1.05, respectively.  It was proven that the more solvent added could linearly decrease the effectiveness of anthocyanin extraction of dragon fruit peel extracts.

Evaluation of the residual solvent content of counterfeit tablets and capsules

2013 ◽  
Vol 81-82 ◽  
pp. 80-88 ◽  
Author(s):  
E. Deconinck ◽  
M. Canfyn ◽  
P.-Y. Sacré ◽  
P. Courselle ◽  
J.O. De Beer
Keyword(s):  
Residual Solvent ◽  
Solvent Content

scholarly journals Multi-Zone Drying Schemes for Lowering the Residual Solvent Content during Multi-Component Drying of Semicrystalline Polymers

2007 ◽  
Vol 25 (6) ◽  
pp. 985-992 ◽  
Author(s):  
Sim-Siong Wong ◽  
Sacide Alsoy Altinkaya ◽  
Surya K. Mallapragada
Keyword(s):  
Semicrystalline Polymers ◽  
Residual Solvent ◽  
Solvent Content

Quality control of residual solvent content in polymeric microparticles

2015 ◽  
Vol 32 (2) ◽  
pp. 107-122 ◽  
Author(s):  
Kalpana Dixit ◽  
Rajani B. Athawale ◽  
Sarabjit Singh
Keyword(s):  
Quality Control ◽  
Residual Solvent ◽  
Solvent Content ◽  
Polymeric Microparticles

Residual solvent content in heatset offset print

1993 ◽  
Vol 16 (7) ◽  
pp. 422-424 ◽  
Author(s):  
Birgit Aurela ◽  
Tapio Räisänen
Keyword(s):  
Residual Solvent ◽  
Solvent Content

scholarly journals KARAKTERISTIK FISIKOKIMIA ANTOSIANIN EKSTRAK KULIT BUAH NAGA MERAH MENGGUNAKAN METODE UAE (Physicochemical Characteristics of Red Dragon Fruit Skin Anthocyanin Extracts using UAE Method)

2018 ◽  
Vol 6 (1) ◽  
pp. 27-38 ◽  
Author(s):  
Asri Widyasanti ◽  
Novira Nurlaily ◽  
Endah Wulandari
Keyword(s):  
Specific Gravity ◽  
Total Yield ◽  
Physicochemical Characteristic ◽  
Control Treatment ◽  
Anthocyanin Content ◽  
Total Anthocyanin ◽  
Residual Solvent ◽  
Solvent Content ◽  
Fruit Skin ◽  
Dragon Fruit

Red dragon fruit skin (Hylocereus polyrhizus) contains naturally pigment as anthocyanin. Anthocyanins can be extracted using conventionally or other method. Ultrasound Assisted Extraction (UAE) is a prospective extraction method because resulting higher yield and shorten time process. The aim of this study was to identify the effect of extraction time and amplitude to the physicochemical characteristic of extract red dragon fruit’s skin. The maceration method was used as control treatment. The parameters observed were total extraction yield, residual solvent content, anthocyanin content, pH, specific gravity and colour. The method used was laboratory experiment by using descriptive analysis. The research showed extraction time at 45 minutes and amplitude number 65% was a best variables extraction which resulted total yield 10.62%, residual solvent content 37.50%, specific gravity 1.2198, total anthocyanin content 29.640 ppm, pH 2.80, respectively. Based on hue angle (23.42o) indicated that the dragon fruit peel extract was red colour. Meanwhile, control treatment resulted a total yield was 9.44%, residual solvent content was 52.67%, specific gravity 1.0609, total anthocyanin content 24.074 ppm, pH 3.06, and hue angle 33.16o. The UAE method revealed a better extraction method than maceration to produce a higher red dragon fruit’s skin extracts and anthocyanin concentration. Keywords: anthocyanin, extract, physicochemical characteristic, red dragon fruit skin, UAE   ABSTRAKKulit buah naga merah (Hylocereus polyrhizus) mengandung pigmen alami sebagai antosianin. Antosianin dapat diekstraksi dengan cara konvensional atau metode lainnya.  Ultrasound Assisted Extraction (UAE) merupakan metode ekstraksi prospektif karena menghasilkan rendemen lebih tinggi dan waktu proses lebih singkat. Penelitian ini bertujuan untuk mengkaji lama waktu ekstraksi dan amplitudo terhadap karakteristik fisikokimia ekstrak kulit buah naga merah. Metode maserasi dilakukan sebagai kontrol. Karakteristik ekstrak yang diamati meliputi rendemen, kadar sisa pelarut, total antosianin, pH, bobot jenis dan warna. Metode penelitian yang digunakan adalah penelitian eksperimental laboratorium dengan analisis deskriptif. Hasil penelitian menunjukkan bahwa kulit buah naga merah dengan amplitudo 65% dan lama ekstraksi 45 menit merupakan perlakuan terbaik dengan rendemen total 10,62%, kadar sisa pelarut 37,50%, bobot jenis 1,2198, kadar total antosianin sebesar 29,640 ppm, pH 2,80. Berdasarkan nilai hue (23,42o) ekstrak tersebut berwarna merah. Sedangkan perlakuan kontrol menghasilkan rendemen total 9,44%, kadar sisa pelarut 52,67%, bobot jenis 1,0609, kadar total antosianin sebesar 24,074 ppm, pH 3,06 dan hue 33,16o. Pada penelitian ini dibuktikan bahwa metode UAE menghasilkan lebih banyak ekstrak kulit buah naga merah dan konsentrasi antosianin lebih tinggi dibandingkan metode maserasi. Kata kunci: antosianin, ekstrak, karakteristik fisikokimia, kulit buah naga merah, UAE

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