A knowledge based approach for elastomer cure kinetic parameters estimation

2013 ◽  
Vol 32 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Eric Leroy ◽  
Anouar Souid ◽  
Alain Sarda ◽  
Rémi Deterre
Keyword(s):  
Kinetic Parameters ◽  
Parameters Estimation ◽  
Knowledge Based ◽  
Cure Kinetic ◽  
Kinetic Parameters Estimation

scholarly journals An Enhanced Segment Particle Swarm Optimization Algorithm for Kinetic Parameters Estimation of the Main Metabolic Model of Escherichia Coli

Processes ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 963
Author(s):  
Mohammed Adam Kunna ◽  
Tuty Asmawaty Abdul Kadir ◽  
Muhammad Akmal Remli ◽  
Noorlin Mohd Ali ◽  
Kohbalan Moorthy ◽  
...  
Keyword(s):  
Particle Swarm Optimization ◽  
Kinetic Parameters ◽  
Optimization Algorithm ◽  
Particle Swarm Optimization Algorithm ◽  
Particle Swarm ◽  
Metabolic Model ◽  
Parameters Estimation ◽  
Swarm Optimization ◽  
Distance Minimization ◽  
Kinetic Parameters Estimation

Building a biologic model that describes the behavior of a cell in biologic systems is aimed at understanding the physiology of the cell, predicting the production of enzymes and metabolites, and providing a suitable data that is valid for bio-products. In addition, building a kinetic model requires the estimation of the kinetic parameters, but kinetic parameters estimation in kinetic modeling is a difficult task due to the nonlinearity of the model. As a result, kinetic parameters are mostly reported or estimated from different laboratories in different conditions and time consumption. Hence, based on the aforementioned problems, the optimization algorithm methods played an important role in addressing these problems. In this study, an Enhanced Segment Particle Swarm Optimization algorithm (ESe-PSO) was proposed for kinetic parameters estimation. This method was proposed to increase the exploration and the exploitation of the Segment Particle Swarm Optimization algorithm (Se-PSO). The main metabolic model of E. coli was used as a benchmark which contained 172 kinetic parameters distributed in five pathways. Seven kinetic parameters were well estimated based on the distance minimization between the simulation and the experimental results. The results revealed that the proposed method had the ability to deal with kinetic parameters estimation in terms of time consumption and distance minimization.

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