Novel amphiphilic diblock copolymers bearing acid-labile oxazolidine moieties: Synthesis, self-assembly and responsive behavior in aqueous solution

Polymer ◽  
2011 ◽  
Vol 52 (8) ◽  
pp. 1755-1765 ◽  
Author(s):  
Qianling Cui ◽  
Feipeng Wu ◽  
Erjian Wang
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Responsive Behavior ◽  
Amphiphilic Diblock Copolymers ◽  
Acid Labile

Synthesis and self-assembly in aqueous solution of amphiphilic diblock copolymers containing hyperbranched polyethylene

Polymer ◽  
2015 ◽  
Vol 57 ◽  
pp. 125-131 ◽  
Author(s):  
BiYun Mai ◽  
Ran Liu ◽  
ZhiYun Li ◽  
Shuo Feng ◽  
Qing Wu ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Amphiphilic Diblock Copolymers

1998 E.W.R. Steacie Award Lecture Asymmetric amphiphilic block copolymers in solution: a morphological wonderland

1999 ◽  
Vol 77 (8) ◽  
pp. 1311-1326 ◽  
Author(s):  
Neil S Cameron ◽  
Muriel K Corbierre ◽  
Adi Eisenberg
Keyword(s):  
Self Assembly ◽  
Diblock Copolymers ◽  
Amphiphilic Block Copolymers ◽  
Polymer Composition ◽  
Selective Solvents ◽  
Thermodynamic And Kinetic Parameters ◽  
Amphiphilic Diblock Copolymers ◽  
Systematic Understanding ◽  
Selection Of ◽  
Qualitative Discussion

Asymmetric amphiphilic diblock copolymers self-assemble in selective solvents. Since 1995, when we first reported the systematic preparation of a sequence of various "crew-cut" aggregate morphologies from this class of copolymer in solution (1), we have identified a vast array of structures and have begun a detailed investigation of the thermodynamic and kinetic parameters that induce morphogenesis. Not only spheres, rods, bilayer and bicontinuous architectures, as well as inverted structures are observed, but also a selection of mixed, combined and much more complex aggregates is documented. All of these aggregates have a phase-separated insoluble core and a crew-cut soluble corona. Thus, all parameters that permit selective modification of the component of either phase or of the interface provide a window for morphological control. By carefully adjusting the polymer chain environment, it has been possible to develop a systematic understanding of morphogenic parameters, which include, among others, polymer composition, common solvent, initial concentration, temperature, type and concentration of added ions, method of preparation, and added homopolymer. To date, more than 30 publications have appeared in the literature from our group alone on this subject. One of the problems inherent with such a complicated system is the taxonomy or classification: which morphologies correspond to equilibrium positions and which are intermediate or trapped? An attempt at a logical presentation of the observed aggregates is given, preceded by a qualitative discussion of the thermodynamic framework for this system. Where possible, the transitions between morphologies are explained in the context of the thermodynamic parameters. Finally, parallels are drawn between the copolymer aggregates and biological architectures.Key words: crew-cut, morphology, block copolymer, self-assembly, amphiphile.

Sphere to Rod Transition of Micelles Formed by Amphiphilic Diblock Copolymers of Vinyl Ethers in Aqueous Solution

1999 ◽  
Vol 32 (3) ◽  
pp. 697-703 ◽  
Author(s):  
Minoru Nakano ◽  
Hideki Matsuoka ◽  
Hitoshi Yamaoka ◽  
Andreas Poppe ◽  
Dieter Richter
Keyword(s):  
Aqueous Solution ◽  
Diblock Copolymers ◽  
Vinyl Ethers ◽  
Amphiphilic Diblock Copolymers

scholarly journals A mild and quantitative route towards well-defined strong anionic/hydrophobic diblock copolymers: synthesis and aqueous self-assembly

2019 ◽  
Vol 10 (45) ◽  
pp. 6109-6115
Author(s):  
Anton H. Hofman ◽  
Remco Fokkink ◽  
Marleen Kamperman
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Diblock Copolymers

Well-defined hydrophobic/strong anionic diblock copolymers were synthesized through a protected hydrophobic intermediate. Their self-assembly in aqueous solution was subsequently studied.

scholarly journals Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles

2021 ◽  
Vol 12 (37) ◽  
pp. 5377-5389
Author(s):  
Riccardo Wehr ◽  
Elena C. dos Santos ◽  
Moritz S. Muthwill ◽  
Vittoria Chimisso ◽  
Jens Gaitzsch ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Membrane Properties ◽  
Giant Unilamellar Vesicles ◽  
Unilamellar Vesicles ◽  
Amphiphilic Diblock Copolymers

Analysis of the membrane properties and stability of fully amorphous small and giant unilamellar vesicles composed of atactic or isotactic poly(butylene oxide)-block-poly(glycidol) (PBO-b-PG) amphiphilic diblock copolymers.

scholarly journals Selenol-Based Nucleophilic Reaction for the Preparation of Reactive Oxygen Species-Responsive Amphiphilic Diblock Copolymers

Polymers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 827
Author(s):  
Xiaowei An ◽  
Weihong Lu ◽  
Jian Zhu ◽  
Xiangqiang Pan ◽  
Xiulin Zhu
Keyword(s):  
Reactive Oxygen Species ◽  
Molecular Weight ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Raft Polymerization ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Amphiphilic Copolymers ◽  
Nucleophilic Reaction ◽  
Amphiphilic Diblock Copolymers

Selenide-containing amphiphilic copolymers have shown significant potential for application in drug release systems. Herein, we present a methodology for the design of a reactive oxygen species-responsive amphiphilic diblock selenide-labeled copolymer. This copolymer with controlled molecular weight and narrow molecular weight distribution was prepared by sequential organoselenium-mediated reversible addition fragmentation chain transfer (Se-RAFT) polymerization and selenol-based nucleophilic reaction. Nuclear magnetic resonance (NMR) and matrix-assisted laser desorption/ionization time-to-flight (MALDI-TOF) techniques were used to characterize its structure. Its corresponding nanomicelles successfully formed through self-assembly from the copolymer itself. Such nanomicelles could rapidly disassemble under oxidative conditions due to the fragmentation of the Se–C bond. Therefore, this type of nanomicelle based on selenide-labeled amphiphilic copolymers potentially provides a new platform for drug delivery.

Sign in / Sign up

Export Citation Format

Share Document