On the 3D structure and catalytic mechanism study of AmiF formamidase of Helicobacter pylori

Polymer ◽  
2007 ◽  
Vol 48 (13) ◽  
pp. 3726-3731 ◽  
Author(s):  
Wei-Wei Han ◽  
Yi-Han Zhou ◽  
Quan Luo ◽  
Yuan Yao ◽  
Ze-Sheng Li
Keyword(s):  
Helicobacter Pylori ◽  
Catalytic Mechanism ◽  
3D Structure ◽  
Mechanism Study

scholarly journals Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes

2018 ◽  
Vol 115 (47) ◽  
pp. 11958-11963 ◽  
Author(s):  
Christian Kubitza ◽  
Florian Bittner ◽  
Carsten Ginsel ◽  
Antje Havemeyer ◽  
Bernd Clement ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Catalytic Mechanism ◽  
Full Range ◽  
3D Structure ◽  
Cytochrome P450 Enzymes ◽  
Oxygenated Compounds ◽  
Online Databases ◽  
Starting Point ◽  
Wide Range ◽  
Nitrogen Containing Compounds

Biotransformation enzymes ensure a viable homeostasis by regulating reversible cycles of oxidative and reductive reactions. The metabolism of nitrogen-containing compounds is of high pharmaceutical and toxicological relevance because N-oxygenated metabolites derived from reactions mediated by cytochrome P450 enzymes or flavin-dependent monooxygenases are in some cases highly toxic or mutagenic. The molybdenum-dependent mitochondrial amidoxime-reducing component (mARC) was found to be an extremely efficient counterpart, which is able to reduce the full range of N-oxygenated compounds and thereby mediates detoxification reactions. However, the 3D structure of this enzyme was unknown. Here we present the high-resolution crystal structure of human mARC. We give detailed insight into the coordination of its molybdenum cofactor (Moco), the catalytic mechanism, and its ability to reduce a wide range of N-oxygenated compounds. The identification of two key residues will allow future discrimination between mARC paralogs and ensure correct annotation. Since our structural findings contradict in silico predictions that are currently made by online databases, we propose domain definitions for members of the superfamily of Moco sulfurase C-terminal (MOSC) domain-containing proteins. Furthermore, we present evidence for an evolutionary role of mARC for the emergence of the xanthine oxidase protein superfamily. We anticipate the hereby presented crystal structure to be a starting point for future descriptions of MOSC proteins, which are currently poorly structurally characterized.

A mechanism study on the efficient conversion of cellulose to acetol over Sn–Co catalysts with low Sn content

2020 ◽  
Vol 22 (19) ◽  
pp. 6579-6587
Author(s):  
Xiaohao Liu ◽  
Xiaodong Liu ◽  
Haiyong Wang ◽  
Tianci Xiao ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Catalytic Mechanism ◽  
Mechanism Study ◽  
Cellulose Conversion ◽  
Co Catalysts ◽  
Efficient Conversion

Sn–Co/SiO2 with low Sn content can effectively catalyze cellulose conversion to acetol, but Sn–Ni/SiO2 cannot. The catalytic mechanism was studied systematically.

Activation of persulfate with 3D urchin-like CoO-CuO microparticles for DBP degradation: A catalytic mechanism study

2019 ◽  
Vol 655 ◽  
pp. 614-621 ◽  
Author(s):  
Xiaofeng Zhang ◽  
Qintie Lin ◽  
Haoyu Luo ◽  
Runlin Huang ◽  
Rongbo Xiao ◽  
...  
Keyword(s):  
Catalytic Mechanism ◽  
Mechanism Study

Highly efficient catalytic conversion of cellulose into acetol over Ni–Sn supported on nanosilica and the mechanism study

2019 ◽  
Vol 21 (20) ◽  
pp. 5647-5656 ◽  
Author(s):  
Xiaohao Liu ◽  
Xiaodong Liu ◽  
Guangyue Xu ◽  
Ying Zhang ◽  
Chenguang Wang ◽  
...  
Keyword(s):  
Catalytic Mechanism ◽  
Catalytic Conversion ◽  
Mechanism Study ◽  
One Pot ◽  
Highly Efficient

61.6% yield of acetol was obtained by one pot conversion of cellulose using Ni–Sn/SiO2 catalysts, and the catalytic mechanism was studied.

Theoretical Analysis of the Catalytic Mechanism of Helicobacter pylori Glutamate Racemase

2012 ◽  
Vol 116 (41) ◽  
pp. 12406-12414 ◽  
Author(s):  
Edgar Mixcoha ◽  
Mireia Garcia-Viloca ◽  
José M. Lluch ◽  
Àngels González-Lafont
Keyword(s):  
Helicobacter Pylori ◽  
Theoretical Analysis ◽  
Catalytic Mechanism ◽  
Glutamate Racemase

Catalytic mechanism study on manganese oxide in the catalytic supercritical water oxidation of nitrobenzene

RSC Advances ◽  
2015 ◽  
Vol 5 (59) ◽  
pp. 47488-47497 ◽  
Author(s):  
Xiuqin Dong ◽  
Ya’nan Zhang ◽  
Yongwei Xu ◽  
Minhua Zhang
Keyword(s):  
Manganese Oxide ◽  
Catalytic Oxidation ◽  
Supercritical Water ◽  
Water Oxidation ◽  
Catalytic Mechanism ◽  
Supercritical Water Oxidation ◽  
Mechanism Study ◽  
Oxidizing Agents

MnO2and Mn2O3transform into each other, and the mixture acts as an electron relay to promote the generation of strong oxidizing agents and the catalytic oxidation of nitrobenzene during catalytic supercritical water oxidation.

scholarly journals Improving the Performance of ZnS Photocatalyst in Degrading Organic Pollutants by Constructing Composites with Ag2O

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1451
Author(s):  
Dequan Yu ◽  
Hao Fang ◽  
Peikai Qiu ◽  
Fancong Meng ◽  
Haixia Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Organic Pollutants ◽  
Catalytic Mechanism ◽  
Radical Scavenging ◽  
Light Response ◽  
High Catalytic Activity ◽  
Mechanism Study ◽  
Catalytic Rate Constant ◽  
Response Range ◽  
Composite Photocatalysts

ZnS is a promising photocatalyst in water purification, whereas its low photon efficiency and poor visible-light response restrict its application. Constructing composites may help solve these problems. In this work, Ag2O was introduced to ZnS for the first time based on their energy band characteristics to form a novel ZnS/Ag2O composite photocatalyst. In the model reaction of degrading methylene blue, the as-designed catalyst exhibited high catalytic activity among a series of ZnS-based composite photocatalysts under similar conditions. The catalytic rate constant was up to 0.138 min−1, which is 27.4- and 15.6-times higher than those of ZnS and Ag2O. This composite degraded 92.4% methylene blue in 50 min, while the ratios were 31.9% and 68.8% for ZnS and Ag2O. Catalytic mechanism study based on photoluminescence and radical-scavenging experiments revealed that the enhanced photocatalytic activity was attributed to the composite structure of ZnS/Ag2O. The structure not only facilitated the separation and transmission of photogenerated carriers but also extended the light response range of the catalyst. The as-designed ZnS/Ag2O composite is promising in degrading organic pollutants in water.

Fundamental understanding of the acidic oxygen evolution reaction: mechanism study and state-of-the-art catalysts

Nanoscale ◽  
2020 ◽  
Vol 12 (25) ◽  
pp. 13249-13275 ◽  
Author(s):  
Zhaoping Shi ◽  
Xian Wang ◽  
Junjie Ge ◽  
Changpeng Liu ◽  
Wei Xing
Keyword(s):  
Reaction Mechanism ◽  
Oxygen Evolution ◽  
Oxygen Evolution Reaction ◽  
Catalytic Mechanism ◽  
State Of The Art ◽  
Mechanism Study ◽  
Fundamental Understanding

A systematic summary of the acidic OER catalytic mechanism and catalysts is given, and some experimental phenomena are explained.

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