scholarly journals Supplementation with high-dose docosahexaenoic acid increases the Omega-3 Index more than high-dose eicosapentaenoic acid

2017 ◽  
Vol 120 ◽  
pp. 8-14 ◽  
Author(s):  
Janie Allaire ◽  
William S. Harris ◽  
Cécile Vors ◽  
Amélie Charest ◽  
Johanne Marin ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
High Dose ◽  
Omega 3

Recent progress on immobilization technology in enzymatic conversion of marine by-products to concentrated omega-3 fatty acids

2021 ◽  
Author(s):  
Yi Liu ◽  
Deepika Dave
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Recent Progress ◽  
Enzymatic Conversion ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Immobilization Technology ◽  
By Products

Marine by-products (heads, frames, trimmings, viscera, skin and scales) have been extensively investigated as sources of marine omega-3 fatty acids (mainly eicosapentaenoic acid and docosahexaenoic acid). Traditionally, extraction of fish...

scholarly journals A Higher Proportion of Eicosapentaenoic Acid (EPA) When Combined with Docosahexaenoic Acid (DHA) in Omega-3 Dietary Supplements Provides Higher Antioxidant Effects in Human Retinal Cells

Antioxidants ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 828 ◽  
Author(s):  
Manuel Saenz de Viteri ◽  
María Hernandez ◽  
Valentina Bilbao-Malavé ◽  
Patricia Fernandez-Robredo ◽  
Jorge González-Zamora ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Cell Viability ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Ethyl Esters ◽  
Omega 3 ◽  
Rpe Cells ◽  
Antioxidant Effects

Retinal pigment epithelium (RPE) is a key regulator of retinal function and is directly related to the transport, delivery, and metabolism of long-chain n-3 polyunsaturated fatty acids (n3-PUFA), in the retina. Due to their functions and location, RPE cells are constantly exposed to oxidative stress. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have shown to have antioxidant effects by different mechanisms. For this reason, we designed an in vitro study to compare 10 formulations of DHA and EPA supplements from different origins and combined in different proportions, evaluating their effect on cell viability, cell proliferation, reactive oxygen species production, and cell migration using ARPE-19 cells. Furthermore, we assessed their ability to rescue RPE cells from the oxidative conditions seen in diabetic retinopathy. Our results showed that the different formulations of n3-PUFAs have a beneficial effect on cell viability and proliferation and are able to restore oxidative induced RPE damage. We observed that the n3-PUFA provided different results alone or combined in the same supplement. When combined, the best results were obtained in formulations that included a higher proportion of EPA than DHA. Moreover, n3-PUFA in the form of ethyl-esters had a worse performance when compared with triglycerides or phospholipid based formulations.

scholarly journals Plasma Docosahexaenoic Acid and Eicosapentaenoic Acid Concentrations Are Positively Associated with Brown Adipose Tissue Activity in Humans

Metabolites ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 388
Author(s):  
Angie S. Xiang ◽  
Corey Giles ◽  
Rebecca K.C. Loh ◽  
Melissa F. Formosa ◽  
Nina Eikelis ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Brown Adipose Tissue ◽  
Cold Exposure ◽  
Surrogate Marker ◽  
Omega 3 ◽  
Bat Activity ◽  
Brown Adipose ◽  
Lipid Species

Brown adipose tissue (BAT) activation is a possible therapeutic strategy to increase energy expenditure and improve metabolic homeostasis in obesity. Recent studies have revealed novel interactions between BAT and circulating lipid species—in particular, the non-esterified fatty acid (NEFA) and oxylipin lipid classes. This study aimed to identify individual lipid species that may be associated with cold-stimulated BAT activity in humans. A panel of 44 NEFA and 41 oxylipin species were measured using mass-spectrometry-based lipidomics in the plasma of fourteen healthy male participants before and after 90 min of mild cold exposure. Lipid measures were correlated with BAT activity measured via 18F-fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT), along with norepinephrine (NE) concentration (a surrogate marker of sympathetic activity). The study identified a significant increase in total NEFA concentration following cold exposure that was positively associated with NE concentration change. Individually, 33 NEFA and 11 oxylipin species increased significantly in response to cold exposure. The concentration of the omega-3 NEFA, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) at baseline was significantly associated with BAT activity, and the cold-induced change in 18 NEFA species was significantly associated with BAT activity. No significant associations were identified between BAT activity and oxylipins.

scholarly journals Rapeseeds a Rich Source of Polyunsaturated Fatty Acids

Proceedings ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 115
Author(s):  
Cristina Emanuela Enăşcuţă ◽  
Elena Emilia Oprescu ◽  
Adrian Radu ◽  
Elena Radu ◽  
Marian Deaconu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Eicosapentaenoic Acid ◽  
Stroke Prevention ◽  
Essential Role ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Human Diet ◽  
Brain Functions

In human diet, polyunsaturated fatty acids (PUFA), have an essential role in optimal brain functions and stroke prevention, specially, omega-3 fatty acids, e.g., 9,12,15-linolenic acid (ALA, 18:3), 5,8,11,14,17-eicosapentaenoic acid (EPA, 20:5), and 4,7,10,13,16,19-docosahexaenoic acid (DHA, 22:6). [...]

scholarly journals Increasing the omega-3 content of traditional meat products by the addition of an underutilised by-product from fish processing

2016 ◽  
Vol 33 (No. 5) ◽  
pp. 431-440 ◽  
Author(s):  
S. Sampels ◽  
T. Zajíc ◽  
J. Mráz
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Meat Products ◽  
Omega 3 ◽  
Fish Processing ◽  
Fish Flesh ◽  
Minced Fish ◽  
Hot Dog

The aim of our study was to find a way to use the minced fish flesh that is separated from the bones of carp after filleting (fish separate). In collaboration with the industry traditional recipes for barbecue sausages, hotdog and Vienna type sausages and liver pâté were modified by replacing a part of the meat with the fish separate. The proportion of nutritionally valuable n-3 fatty acids – eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) calculated together was 74, 54, 109, and 77 mg/100 g product in the barbecue sausage, hot dog, Vienna sausage and pâté, respectively. This means 29.6, 21.6, 43.6, and 30.8% of the daily recommended intake according to EFSA. 

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