scholarly journals Efficacy of Omega-3 Fatty Acid Supplements (Eicosapentaenoic Acid and Docosahexaenoic Acid) in the Secondary Prevention of Cardiovascular Disease

2012 ◽  
Vol 172 (9) ◽  
pp. 686 ◽  
Author(s):  
Seung-Kwon Myung
Keyword(s):  
Cardiovascular Disease ◽  
Fatty Acid ◽  
Docosahexaenoic Acid ◽  
Secondary Prevention ◽  
Eicosapentaenoic Acid ◽  
Omega 3 ◽  
Omega 3 Fatty Acid ◽  
Prevention Of Cardiovascular Disease

scholarly journals Efficient Enrichment of Retinal DHA with Dietary Lysophosphatidylcholine-DHA: Potential Application for Retinopathies

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3114
Author(s):  
Dhavamani Sugasini ◽  
Poorna C. R. Yalagala ◽  
Papasani V. Subbaiah
Keyword(s):  
Risk Factor ◽  
Fatty Acid ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Fish Oil ◽  
Potential Application ◽  
Eye Diseases ◽  
Krill Oil ◽  
Omega 3 ◽  
Omega 3 Fatty Acid

Although decreased retinal docosahexaenoic acid (DHA) is a known risk factor for retinopathy, currently available omega-3 fatty acid supplements, which are absorbed as triacylglycerol (TAG), do not significantly enrich retinal DHA. We tested the hypothesis that lysophospahtidylcholine (LPC)-DHA which is absorbed as phospholipid, would efficiently increase retinal DHA because of the presence of LPC-specific transporter at the blood–retina barrier. In normal rats, LPC-DHA and di-DHA phosphatidylcholine (PC), which generates LPC-DHA during digestion, increased retinal DHA by 101% and 45%, respectively, but TAG-DHA had no significant effect at the same dose (40 mg/kg, 30 days). In normal mice, both sn-1 DHA LPC and sn-2 DHA LPC increased retinal DHA by 80%, but free DHA had no effect. Lipase-treated krill oil (which contains LPC-DHA and LPC-EPA (eicosapentaenoic acid), but not normal krill oil (which has little LPC), increased both retinal DHA (+76%) and EPA (100-fold). Fish oil, however, had no effect, whether lipase-treated or not. These studies show that retinal DHA can be efficiently increased by dietary LPC-DHA, but not by TAG-DHA or free DHA. Since DHA is known to be protective against retinopathy and other eye diseases, this study provides a novel nutraceutical approach for the prevention/treatment of these diseases.

Prime Australian lamb supplies key nutrients for human health

2010 ◽  
Vol 50 (12) ◽  
pp. 1115 ◽  
Author(s):  
L. Pannier ◽  
E. N. Ponnampalam ◽  
G. E. Gardner ◽  
D. L. Hopkins ◽  
A. J. Ball ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Average Level ◽  
Omega 3 ◽  
Good Source ◽  
Men And Women ◽  
Omega 3 Fatty Acid ◽  
Lamb Meat ◽  
Iron And Zinc

This study investigated genetic and non-genetic factors affecting the iron, zinc and omega-3 fatty acid levels of fresh lamb meat. Results from the 2007 progeny of the Australian Sheep Industry Cooperative Research Centre Information Nucleus flock, ~2000 lambs, are presented here. The average level of iron and zinc in lamb muscle was 2.05 and 2.31 mg/100 g, respectively. The iron level was 103% of that required to claim lamb as a ‘good source’ of iron for men of all ages and women older than 50 years, and the average level of zinc was 116% of that required to claim lamb as a ‘good source’ of zinc for women, but was insufficient for a ‘good source’ claim for men. The iron and zinc content of muscle were affected (P < 0.001) by age at slaughter, sex, site at which the lambs were reared, and sire (independent of breed). Lambs from all sites reached the ‘source’ claim for iron for all adults and lambs from all sites, expect lambs from the Cowra and Hamilton sites, had greater iron levels than that required for a ‘good source’ claim for men and women over 50 years old. For zinc, all sites reached the ‘source’ and ‘good source’ claim for men and women, respectively. The major sources of variation in omega-3 fatty acid levels were site and kill group within site (P < 0.001), most likely reflecting nutritional differences associated with the availability of green feed. The eicosapentaenoic acid + docosahexaenoic acid values for all sites indicated that lambs from the Cowra, Rutherglen and Struan sites had adequate levels for a ‘source’ claim of omega-3. The overall average level of eicosapentaenoic acid + docosahexaenoic acid in lamb meat was 23.5 mg/100 g, which is higher than the level required to claim lamb as a ‘source’ of omega-3. The effect of sire on omega-3 fatty acid level was small, but statistically significant (P < 0.001). These results confirm that lamb can represent a ‘source’ or ‘good source’ of these nutrients.

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