Inhibitors of phenylalanine ammonia-lyase: Substituted derivatives of 2-aminoindane-2-phosphonic acid and 1-aminobenzylphosphonic acid

2007 ◽  
Vol 68 (4) ◽  
pp. 407-415 ◽  
Author(s):  
Piotr Miziak ◽  
Jerzy Zoń ◽  
Nikolaus Amrhein ◽  
Roman Gancarz
Keyword(s):  
Phosphonic Acid ◽  
Phenylalanine Ammonia Lyase ◽  
Derivatives Of

Functional derivatives of (bromomethyl)phosphonic acid

2004 ◽  
Vol 74 (8) ◽  
pp. 1168-1170
Author(s):  
L. K. Kibardina ◽  
M. A. Pudovik ◽  
R. M. Kamalov ◽  
A. N. Pudovik
Keyword(s):  
Phosphonic Acid ◽  
Functional Derivatives ◽  
Derivatives Of

scholarly journals Copper(II) Complexes of Organophoshonic Acids-A Comparative Study

2011 ◽  
Vol 8 (s1) ◽  
pp. S271-S281
Author(s):  
B. Venkateswara Rao ◽  
D. M. Puri
Keyword(s):  
Phosphonic Acid ◽  
Octahedral Geometry ◽  
Spectral Studies ◽  
Diphosphonic Acid ◽  
Paramagnetic Resonance ◽  
Diethylene Triamine ◽  
Coordination Sites ◽  
Infrared Spectral ◽  
Electron Paramagnetic ◽  
Derivatives Of

Polynuclear copper(II) derivatives of 1-hydroxyethylidenediphosphonic acid (HEDP), 1-aminoethylidenediphosphonic acid (AEDP, H4L),α-aminobenzylidene diphosphonic acid (ABDP, H4L), 1-amino-2-carboxyethane- 1,1-diphosphonic acid (ACEDP, H5L), 1,3 diaminopropane-1,1,3,3-tetra-phosphonic acid (DAPTP, H8L), Ethylenediamine-N,N'-bis (dimethyl-methylenephosphonic) acid (EDBDMPO, H4L),o-phenylene-diamine-N,N'-bis (dimethylmethylenephosphonic) acid (PDBDMPO, H4L), diethylene triamine –N,N,N',N',N"N-penta (methylene phosphonic) acid (DETAPMPO, H10L) and diethylene triamine –N,N"-bis (dimethyl methylene phosphonic) acid (DETBDMPO, H4L) have been prepared in aqueous medium. The general formula of derivatives from elemental analysis was found to be Cu2L.XH2O (in case of AEDP, ABDP, EDBDMPO, PDBDMPO, DETBDMPO), Cu5L2.XH2O (in case of ACEDP) Cu4L.XH2O, Cu2H4L. XH2O (in case of DAPTP) and Cu5L.XH2O (in case of DETAPMPO). The electronic spectra have shown them to be six coordinated with slight distortion from octahedral geometry. Antiferromagnetism was inferred from magnetic moment data. Infrared spectral studies were carried out to determine coordination sites. EPR (Electron Paramagnetic Resonance) spectra that supports the presence of tetragonal distortion and antiferromagnetic behaviour, have also been studied.

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