scholarly journals Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects

2016 ◽  
Vol 630 ◽  
pp. 1-84 ◽  
Author(s):  
X. Lu ◽  
G.V. Naidis ◽  
M. Laroussi ◽  
S. Reuter ◽  
D.B. Graves ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Biological Effects ◽  
Reactive Species ◽  
Atmospheric Pressure Plasmas ◽  
Non Equilibrium

Liquid Droplets in Contact With Cold Non-Equilibrium Atmospheric Pressure Plasmas

2016 ◽  
Author(s):  
Christopher A. Vasko ◽  
Christina G. Giannopapa
Keyword(s):  
Health Care ◽  
Atmospheric Pressure ◽  
Industrial Applications ◽  
Plasma Jets ◽  
Extreme Conditions ◽  
Scale Production ◽  
Atmospheric Pressure Plasmas ◽  
Remote Locations ◽  
Compact Size ◽  
Non Equilibrium

Recently, cold, non-equilibrium atmospheric pressure plasmas (CAPs) and their active chemistry have been extensively investigated to the benefit of a wide array of applications such as biomedical and industrial applications mainly in the area of materials processing and chemical synthesis, amongst many others. In general, these plasmas operate at standard conditions (i.e. 1 atm, 300K), are small (∼ cm) and rather simple to operate in comparison to other plasmas. Their complex chemistry gives rise to a wide array of both stable and transient reactive species: such as O3, H2O2, OH and NOx, next to charged species and (V)UV-radiation. This chemistry is the reason for their wide spread application and has already found many industrial applications from waste water treatment, stain free detergents and industrial scale production of oxidants. In recent years, bactericidal effects of CAPs gained increasing attention for applications such as dermatology, disinfection, dentistry and cancer treatment or stimulated blood coagulation. This paper aims to highlight recent research into new biological applications for complex mission scenarios involving humans in remote locations using CAPs for disinfection, bleaching or wound healing. Results using radiofrequency plasma jets for the inactivation of Pseudomonas aeruginosa are summarized, highlighting the importance of liquid plasma interactions. Work with such a CAP paved the way for a promising application in the field of biomedical applications presented here. It involves surface barrier discharges which can be used to treat larger surfaces compared to jets. Their physical construction, using floating or contained electrodes, offer a convenient way of controlling electrical current on a large scale, 3D treatment of both conducting and insulating surfaces with minimal heating. These devices may be tailored to specific skin treatments, allowing fast and effective treatment of larger skin surfaces while following the shape of the skin. This might reduce the need for bactericidal agents and would be a valuable application to assist humans in remote locations. These emerging technologies could be essential both for human health care under extreme conditions, as well as for research itself (sterilisation of tools and large areas, etc.). Especially in the absence of abundant resources (antibiotic agents, disinfectants and the like) alternative approaches to support humans in isolated locations have to be developed. Applications based on a good understanding of plasma chemistry would empower health care under extreme conditions to efficiently use and manage in situ resources. Their low mass, compact size, low power consumption and high reliability could make them essential use under extreme conditions.

Non-equilibrium steady-state kinetics of He-air atmospheric pressure plasmas

2017 ◽  
Vol 24 (1) ◽  
pp. 013501 ◽  
Author(s):  
Tz. B. Petrova ◽  
G. M. Petrov ◽  
D. R. Boris ◽  
S. G. Walton
Keyword(s):  
Steady State ◽  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasmas ◽  
Steady State Kinetics ◽  
Kinetics Of ◽  
Non Equilibrium

scholarly journals Applications of Cold Atmospheric Pressure Plasma in Dentistry

2021 ◽  
Vol 11 (5) ◽  
pp. 1975
Author(s):  
Aline C. Borges ◽  
Konstantin G. Kostov ◽  
Rodrigo S. Pessoa ◽  
Geraldo M.A. de Abreu ◽  
Gabriela de M.G. Lima ◽  
...  
Keyword(s):  
Atmospheric Pressure ◽  
Biological Effects ◽  
Atmospheric Pressure Plasma ◽  
Reactive Species ◽  
Electrically Conducting ◽  
Pressure Plasma ◽  
Cold Plasmas ◽  
Cold Atmospheric Pressure Plasma ◽  
Ultraviolet Photons ◽  
Oral Oncology

Plasma is an electrically conducting medium that responds to electric and magnetic fields. It consists of large quantities of highly reactive species, such as ions, energetic electrons, exited atoms and molecules, ultraviolet photons, and metastable and active radicals. Non-thermal or cold plasmas are partially ionized gases whose electron temperatures usually exceed several tens of thousand degrees K, while the ions and neutrals have much lower temperatures. Due to the presence of reactive species at low temperature, the biological effects of non-thermal plasmas have been studied for application in the medical area with promising results. This review outlines the application of cold atmospheric pressure plasma (CAPP) in dentistry for the control of several pathogenic microorganisms, induction of anti-inflammatory, tissue repair effects and apoptosis of cancer cells, with low toxicity to healthy cells. Therefore, CAPP has potential to be applied in many areas of dentistry such as cariology, periodontology, endodontics and oral oncology.

scholarly journals Non-equilibrium synergistic effects in atmospheric pressure plasmas

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Heng Guo ◽  
Xiao-Ning Zhang ◽  
Jian Chen ◽  
He-Ping Li ◽  
Kostya Ostrikov
Keyword(s):  
Atmospheric Pressure ◽  
Synergistic Effects ◽  
Atmospheric Pressure Plasmas ◽  
Non Equilibrium

scholarly journals The fate of plasma-generated oxygen atoms in aqueous solutions: non-equilibrium atmospheric pressure plasmas as an efficient source of atomic O(aq)

2018 ◽  
Vol 20 (17) ◽  
pp. 12037-12042 ◽  
Author(s):  
J. Benedikt ◽  
M. Mokhtar Hefny ◽  
A. Shaw ◽  
B. R. Buckley ◽  
F. Iza ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Atmospheric Pressure ◽  
Atmospheric Pressure Plasmas ◽  
Non Equilibrium ◽  
Oxygen Atoms

It is demonstrated with help of 18O2 labeling that O(aq) is stable in water and can directly react with dissolved molecules.

scholarly journals Cold Atmospheric Pressure Plasma Technology for Biomedical Application

2021 ◽  
Author(s):  
Rakesh Ruchel Khanikar ◽  
Heremba Bailung
Keyword(s):  
Atmospheric Pressure ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Biological Effects ◽  
Relative Concentration ◽  
Density Measurement ◽  
Reactive Species ◽  
Gas Temperature ◽  
Plasma Technology ◽  
Plasma Parameters

Cold plasma generated in an open environment with a temperature nearly around room temperature has recently been a topic of great importance. It has unlocked the door of plasma application in a new direction: biomedical applications. Cold atmospheric pressure (CAP) plasma comprises various neutral and charged reactive species, UV radiations, electric current/fields etc., which have several impactful effects on biological matter. Some of the significant biological effects of CAP plasma are inactivation of microorganism, stimulation of cell proliferation and tissue regeneration, destruction of cells by initializing apoptosis etc. Although the detailed mechanism of action of plasma on biomaterials is still not completely understood, some basic principles are known. Studies have indicated that the reactive oxygen species and nitrogen species (ROS, RNS) play a crucial role in the observed biological effects. In this perspective, this chapter first provides a brief discussion on the fundamentals of CAP plasma and its generation methods. Then a discussion on the optical diagnostics methods to characterize the plasma is provided. Optical emission spectroscopy (OES) is used to identify the reactive species and to measure their relative concentration. Other important plasma parameters such as gas temperature, electron/excitation temperature and electron density measurement methods using OES have also been discussed. Then a discussion on the application of CAP plasma in biomedical field is provided. A thorough understanding of biochemical reaction mechanisms involving highly reactive plasma species will further improve and extend CAP plasma technology in biomedical applications.

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