Optimal size for heating efficiency of superparamagnetic dextran-coated magnetite nanoparticles for application in magnetic fluid hyperthermia

2018 ◽  
Vol 549 ◽  
pp. 84-87 ◽  
Author(s):  
Zhila Shaterabadi ◽  
Gholamreza Nabiyouni ◽  
Meysam Soleymani
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
S. P. Tsopoe ◽  
C. Borgohain ◽  
Rushikesh Fopase ◽  
Lalit M. Pandey ◽  
J. P. Borah

Abstract Exchange bias (EB) of magnetic nanoparticles (MNPs) in the nanoscale regime has been extensively studied by researchers, which have opened up a novel approach in tuning the magnetic anisotropy properties of magnetic nanoparticles (MNPs) in prospective application of biomedical research such as magnetic hyperthermia. In this work, we report a comparative study on the effect of magnetic EB of normal and inverted core@shell (CS) nanostructures and its influence on the heating efficiency by synthesizing Antiferromagnetic (AFM) NiO (N) and Ferrimagnetic (FiM) Fe3O4 (F). The formation of CS structures for both systems is clearly authenticated by XRD and HRTEM analyses. The magnetic properties were extensively studied by Vibrating Sample Magnetometer (VSM). We reported that the inverted CS NiO@Fe3O4 (NF) MNPs have shown a greater EB owing to higher uncompensated spins at the interface of the AFM, in comparison to the normal CS Fe3O4@NiO (FN) MNPs. Both the CS systems have shown higher SAR values in comparison to the single-phased F owing to the EB coupling at the interface. However, the higher surface anisotropy of F shell with more EB field for NF enhanced the SAR value as compared to FN system. The EB coupling is hindered at higher concentrations of NF MNPs because of the enhanced dipolar interactions (agglomeration of nanoparticles). Both the CS systems reach to the hyperthermia temperature within 10 min. The cyto-compatibility analysis resulted in the excellent cell viability (> 75%) for 3 days in the presence of the synthesized NPs upto 1 mg/ml. These observations endorsed the suitability of CS nanoassemblies for magnetic fluid hyperthermia applications.


2009 ◽  
Vol 321 (10) ◽  
pp. 1493-1496 ◽  
Author(s):  
Makoto Suto ◽  
Yasutake Hirota ◽  
Hiroaki Mamiya ◽  
Asaya Fujita ◽  
Ryo Kasuya ◽  
...  

ACS Omega ◽  
2020 ◽  
Vol 5 (41) ◽  
pp. 26357-26364
Author(s):  
Jesús Antonio Fuentes-García ◽  
Alex Carvalho Alavarse ◽  
Ana Carolina Moreno Maldonado ◽  
Alfonso Toro-Córdova ◽  
Manuel Ricardo Ibarra ◽  
...  

2019 ◽  
Vol 471 ◽  
pp. 504-512 ◽  
Author(s):  
Matteo Avolio ◽  
Andrea Guerrini ◽  
Francesca Brero ◽  
Claudia Innocenti ◽  
Claudio Sangregorio ◽  
...  

Author(s):  
Junfeng Jiang ◽  
Ruoyu Hong ◽  
Xiaohui Zhang ◽  
Hongzhong Li

Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.


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