scholarly journals Simple Sonochemical Method to Optimize the Heating Efficiency of Magnetic Nanoparticles for Magnetic Fluid Hyperthermia

ACS Omega ◽  
2020 ◽  
Vol 5 (41) ◽  
pp. 26357-26364
Author(s):  
Jesús Antonio Fuentes-García ◽  
Alex Carvalho Alavarse ◽  
Ana Carolina Moreno Maldonado ◽  
Alfonso Toro-Córdova ◽  
Manuel Ricardo Ibarra ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Fluid ◽  
Sonochemical Method ◽  
Magnetic Fluid Hyperthermia ◽  
Heating Efficiency

scholarly journals A comparative investigation of normal and inverted exchange bias effect for magnetic fluid hyperthermia applications

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
S. P. Tsopoe ◽  
C. Borgohain ◽  
Rushikesh Fopase ◽  
Lalit M. Pandey ◽  
J. P. Borah
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Fluid ◽  
Exchange Bias ◽  
Comparative Investigation ◽  
Bias Effect ◽  
Exchange Bias Effect ◽  
Magnetic Fluid Hyperthermia ◽  
Heating Efficiency ◽  
Compatibility Analysis ◽  
Novel Approach

Abstract Exchange bias (EB) of magnetic nanoparticles (MNPs) in the nanoscale regime has been extensively studied by researchers, which have opened up a novel approach in tuning the magnetic anisotropy properties of magnetic nanoparticles (MNPs) in prospective application of biomedical research such as magnetic hyperthermia. In this work, we report a comparative study on the effect of magnetic EB of normal and inverted core@shell (CS) nanostructures and its influence on the heating efficiency by synthesizing Antiferromagnetic (AFM) NiO (N) and Ferrimagnetic (FiM) Fe3O4 (F). The formation of CS structures for both systems is clearly authenticated by XRD and HRTEM analyses. The magnetic properties were extensively studied by Vibrating Sample Magnetometer (VSM). We reported that the inverted CS NiO@Fe3O4 (NF) MNPs have shown a greater EB owing to higher uncompensated spins at the interface of the AFM, in comparison to the normal CS Fe3O4@NiO (FN) MNPs. Both the CS systems have shown higher SAR values in comparison to the single-phased F owing to the EB coupling at the interface. However, the higher surface anisotropy of F shell with more EB field for NF enhanced the SAR value as compared to FN system. The EB coupling is hindered at higher concentrations of NF MNPs because of the enhanced dipolar interactions (agglomeration of nanoparticles). Both the CS systems reach to the hyperthermia temperature within 10 min. The cyto-compatibility analysis resulted in the excellent cell viability (> 75%) for 3 days in the presence of the synthesized NPs upto 1 mg/ml. These observations endorsed the suitability of CS nanoassemblies for magnetic fluid hyperthermia applications.

In-gel study of the effect of magnetic nanoparticles immobilization on their heating efficiency for application in Magnetic Fluid Hyperthermia

2019 ◽  
Vol 471 ◽  
pp. 504-512 ◽  
Author(s):  
Matteo Avolio ◽  
Andrea Guerrini ◽  
Francesca Brero ◽  
Claudia Innocenti ◽  
Claudio Sangregorio ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia ◽  
Heating Efficiency

scholarly journals Evaluation of magnetic nanoparticles for magnetic fluid hyperthermia

2019 ◽  
Vol 36 (1) ◽  
pp. 686-700 ◽  
Author(s):  
Olivia L. Lanier ◽  
Olena I. Korotych ◽  
Adam G. Monsalve ◽  
Dayita Wable ◽  
Shehaab Savliwala ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Fluid ◽  
Magnetic Fluid Hyperthermia

scholarly journals Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia

2017 ◽  
Vol 3 (2) ◽  
pp. 457-460 ◽  
Author(s):  
Ulrich Engelmann ◽  
Eva Miriam Buhl ◽  
Martin Baumann ◽  
Thomas Schmitz-Rode ◽  
Ioana Slabu
Keyword(s):  
Magnetic Nanoparticles ◽  
Local Heating ◽  
Magnetic Hyperthermia ◽  
Cellular Level ◽  
Tumor Site ◽  
Tumor Treatment ◽  
Tumor Cell Death ◽  
Magnetic Fluid Hyperthermia ◽  
Heating Efficiency ◽  
Intracellular Compartments

AbstractMagnetic fluid hyperthermia (MFH) is a promising approach for organ-confined tumor treatment. In MFH, magnetic nanoparticles (MNP) are magnetically targeted at the tumor site and heated in an alternating magnetic field. The heat produced by the MNP is used to cause tumor cell death. At the tumor site, MNP bind to the cell membrane and form agglomerates before they are internalized into the intracellular compartments. Intracellular immobilization and the formation of agglomerates influence heating properties of MNP making it difficult to control the local heating inside the tumor. In this study, we investigated MNP agglomerated samples for their heating efficiency. We found an increase in heating of 22 % upon agglomeration. If MNP are additionally immobilized, however, the heating decreases by 30 %. Consequently, due to the binding of bigger MNP agglomerates at cellular level, heating efficiency inside tumors is assumed to decrease.

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