scholarly journals The effects of novelty on food consumption in male and female rats

2020 ◽  
Vol 223 ◽  
pp. 112970
Author(s):  
Eliza M. Greiner ◽  
Gorica D. Petrovich
2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Neena Singla ◽  
Ramandeep Kaur Thind ◽  
Amrit Kaur Mahal

Rodent repellents are chemicals which by taste or odour or possibly by both will prevent animal from feeding or gnawing. Such substances may be used in protecting an area from rodent infestation or in protecting packaged food, packing materials, electric cables, and other important vulnerable materials. Mature and healthy house rat,Rattus rattusof both sexes, was exposed to 5, 10, and 20% eucalyptus oil applied as spray in laboratory pens in bichoice tests. Each concentration was applied through three different modes of application, that is, daily, once, and alternatively in a week. Repellent effect of the oil was assessed based on food consumption from treated and untreated sides for four days. In overall, food consumption was significantly (P<0.0001) low from treatment side compared to the untreated side indicating significant repellent effect of the oil at all the three concentrations tested. Repellent effect of the oil was, however, not found to differ significantly between the two sexes. Percent repellency in both male and female rats was apparently more with daily application of 5 and 10% eucalyptus oil. Present studies reveal the potential of eucalyptus oil in repelling awayR. rattus; however, further studies may be conducted to enhance the persistence of repellent effect for longer period of time.


1953 ◽  
Vol 31 (5) ◽  
pp. 377-386
Author(s):  
Jules Tuba ◽  
G. Stuart Wiberg

A dextrinogenic micromethod was used to establish serum amylase levels in adult male and female rats which were maintained on a standard laboratory diet. A highly significant difference was found to exist between the activities of the enzyme in the male and female rats. The effect of fasting, and of limiting food consumption, indicated a highly significant correlation between daily food intake and serum amylase levels. The polyphagia manifested by alloxan diabetic rats was not reflected in abnormally high amylase activity, as might be expected, but there was a departure from the normal response to the levels of food ingested each day. Oestradiol dipropionate and testosterone propionate were injected into normal male and female rats for seven days. Treatment with male hormone produced no significant variation in food consumption or serum amylase activity in either sex. Injections with oestradiol resulted in significantly lowered food intake in both sexes, but only in the case of males was there an accompanying fall in enzyme levels. On the basis of the experiments described in this paper it is seen that rat serum amylase consists of two fractions, and that the major portion may be considered to be of an adaptive nature. This adaptive portion appears to a large measure to be a reflection of the total daily food intake, which may be influenced by certain factors, such as sex hormones and alloxan diabetes.


1983 ◽  
Vol 2 (6) ◽  
pp. 371-378 ◽  
Author(s):  
Peter J. Becci ◽  
Kenneth A. Voss ◽  
William D. Johnson ◽  
Michael A. Gallo ◽  
John G. Babish

Wistar rats (25/ sex • group) and CD-1 mice (30/sex • group) were fed either a control diet or diet supplemented with N,N-dimethylformamide at the levels of 215, 750, and 2500 ppm for rats and 160,540, and 1850 ppm for mice. The duration of feeding was 104 days for rats and 119 days for mice. Body weight gain, food consumption, hematological and clinical chemical data, ophthalmic, gross, and microscopic examinations were used to study possible toxic or pathologic effects. A significant reduction in body weight gain was noted for male and female rats at the high dosage level. Food consumption in male rats at the high-dosage level and female rats at both the middle- and high-dosage levels was decreased. A significant dose-related increase in relative liver weights was noted in male and female rats. Absolute liver weights of male rats were comparable among groups, however, a dose-related increase was noted in female rats. No significant differences among groups were noted in body weight and food consumption data for mice. A significant dose-related increase in relative and absolute liver weights was noted in male and female mice. Histopathological evaluation revealed no evidence of a toxic effect related to feeding of N.N-dimethylformamide to Wistar rats and CD-1 mice. The increase in liver weight is considered to be a normal phenomenon (physiological adaptation) required for the biotransformation of N,N-dimethylformamide. The lack of hepatotoxicity in the present study may be the result of feeding N,N-dimethylf ormamide over waking hours versus bolus dosing (in other studies) in which hepatotoxicity was noted.


2000 ◽  
Vol 96 (1-2) ◽  
pp. 45-51 ◽  
Author(s):  
Andrea C. Haynes ◽  
Brian Jackson ◽  
Helen Chapman ◽  
Mohammed Tadayyon ◽  
Amanda Johns ◽  
...  

1961 ◽  
Vol 38 (1) ◽  
pp. 50-58 ◽  
Author(s):  
N. E. Borglin ◽  
L. Bjersing

ABSTRACT Oestriol (oestra-1,3,5(10)-triene-3,16α,17β-triol) is a weakly oestrogenic substance which, however, in contrast to what was formerly believed, is of physiological significance. Its effect is localized largely to the uterine cervix and vagina. Clinical experience argues both for and against an effect on the pituitary gland. This investigation is concerned with the morphological changes in the pituitary gland and adrenal cortex of gonadectomized male and female rats after the injection of oestriol. It was found that oestriol has the same type of action on these glands as other oestrogens, but under the experimental conditions used, this effect proved much weaker than that produced by oestradiol (oestra-1,3,5(10)-triene-3,17β-diol).


1973 ◽  
Vol 74 (1) ◽  
pp. 88-104 ◽  
Author(s):  
T. Jolín ◽  
M. J. Tarin ◽  
M. D. Garcia

ABSTRACT Male and female rats of varying ages were placad on a low iodine diet (LID) plus KClO4 or 6-propyl-2-thiouracil (PTU) or on the same diet supplemented with I (control rats). Goitrogenesis was also induced with LID plus PTU in gonadectomized animals of both sexes. The weight of the control and goitrogen treated animals, and the weight and iodine content of their thyroids were determined, as well as the plasma PBI, TSH, insulin and glucose levels. The pituitary GH-like protein content was assessed by disc electrophoresis on polyacrylamide gels. If goitrogenesis was induced in young rats of both sexes starting with rats of the same age, body weight (B.W.) and pituitary growth hormone (GH) content, it was found that both the males and females developed goitres of the same size. On the contrary, when goitrogenesis was induced in adult animals, it was found that male rats, that had larger B.W. and pituitary GH content than age-paired females, developed larger goitres. However, both male and female rats were in a hypothyroid condition of comparable degree as judged by the thyroidal iodine content and the plasma PBI and TSH levels. When all the data on the PTU or KClO4-treated male and female rats of varying age and B.W. were considered together, it was observed that the weights of the thyroids increased proportionally to B.W. However, a difference in the slope of the regression of the thyroid weight over B.W. was found between male and female rats, due to the fact that adult male rats develop larger goitres than female animals. In addition, in the male rats treated with PTU, gonadectomy decreased the B.W., pituitary content of GH-like protein and, concomitantly, the size of the goitre decreased; an opposite effect was induced by ovariectomy on the female animals. However, when goitrogenesis was induced in weight-paired adult rats of both sexes, the male animals still developed larger goitres than the females. Among all the parameters studied here, the only ones which appeared to bear a consistent relationship with the size of the goitres in rats of different sexes, treated with a given goitrogen, were the rate of body growth and the amount of a pituitary GH-like protein found before the onset of the goitrogen treatment. Moreover, though the pituitary content of the GH-like protein decreased as a consequence of goitrogen treatment, it was still somewhat higher in male that in female animals. The present results suggest that GH may somehow be involved in the mechanism by which male and female rats on goitrogens develop goitres of different sizes, despite equally high plasma TSH levels.


Sign in / Sign up

Export Citation Format

Share Document