scholarly journals Neural integration of satiation and food reward: Role of GLP-1 and orexin pathways

2014 ◽  
Vol 136 ◽  
pp. 194-199 ◽  
Author(s):  
Diana L. Williams
Keyword(s):  
Food Reward ◽  
Neural Integration

Role of MicroRNA Genes miR-1000 and miR-375 in Forming Olfactory Conditional Memory in Drosophila melanogaster

MicroRNA ◽  
2020 ◽  
Vol 09 ◽  
Author(s):  
Sadniman Rahman ◽  
Chaity Modak ◽  
Mousumi Akter ◽  
Mohammad Shamimul Alam
Keyword(s):  
Learning And Memory ◽  
Short Term Memory ◽  
Memory Loss ◽  
Memory Formation ◽  
Neural Integration ◽  
Significant Difference ◽  
Locomotion Speed ◽  
Microrna Genes ◽  
With Memory

Background: Learning and memory is basic aspects in neurogenetics as most of the neurological disorders start with dementia or memory loss. Several genes associated with memory formation have been discovered. MicroRNA genes miR-1000 and miR-375 were reported to be associated with neural integration and glucose homeostasis in some insects and vertebrates. However, neuronal function of these genes is yet to be established in D. melanogaster. Objective: Possible role of miR-1000 and miR-375 in learning and memory formation in this fly has been explored in the present study. Methods: Both appetitive and aversive olfactory conditional learning were tested in the miR-1000 and miR-375 knockout (KO) strains and compared with wild one. Five days old third instar larvae were trained by allowing them to be associated with an odor with reward (fructose) or punishment (salt). Then, the larvae were tested to calculate their preferences to the odor trained with. Learning index (LI) values and larval locomotion speed were calculated for all strains. Results: No significant difference was observed for larval locomotion speed in mutant strains. Knockout strain of miR-1000 showed significant deficiency in both appetitive and aversive memory formation whereas miR-375 KO strain showed a significantly lower response only in appetitive one. Conclusion: The results of the present study indicate important role played by these two genes in forming short-term memory in D. melanogaster.

scholarly journals The effect of within-meal protein content and taste on subsequent food choice and satiety

2011 ◽  
Vol 106 (5) ◽  
pp. 779-788 ◽  
Author(s):  
Sanne Griffioen-Roose ◽  
Monica Mars ◽  
Graham Finlayson ◽  
John E. Blundell ◽  
Cees de Graaf
Keyword(s):  
Protein Content ◽  
Food Choice ◽  
Food Preference ◽  
Food Reward ◽  
Meal Protein ◽  
Sensory Qualities ◽  
Ad Libitum ◽  
Underlying Processes ◽  
Insight Into

It is posed that protein intake is tightly regulated by the human body. The role of sensory qualities in the satiating effects of protein, however, requires further clarification. Our objective was to determine the effect of within-meal protein content and taste on subsequent food choice and satiety. We used a cross-over design whereby sixty healthy, unrestrained subjects (twenty-three males and thirty-seven females) with a mean age of 20·8 (sd 2·1) years and a mean BMI of 21·5 (sd 1·6) kg/m2 were offered one of four isoenergetic preloads (rice meal) for lunch: two low in protein (about 7 % energy derived from protein) and two high in protein (about 25 % energy from protein). Both had a sweet and savoury version. At 30 min after preload consumption, subjects were offered an ad libitum buffet, consisting of food products differing in protein content (low/high) and taste (sweet/savoury). In addition, the computerised Leeds Food Preference Questionnaire (LFPQ) was run to assess several components of food reward. The results showed no effect of protein content of the preloads on subsequent food choice. There was an effect of taste; after eating the savoury preloads, choice and intake of sweet products were higher than of savoury products. No such preference was seen after the sweet preloads. No differences in satiety were observed. To conclude, within one eating episode, within-meal protein content in these quantities seems not to have an effect on subsequent food choice. This appears to be mostly determined by taste, whereby savoury taste exerts the strongest modulating effect. The results of the LFPQ provided insight into underlying processes.

scholarly journals The role of food reward during weight management – a systematic review

2018 ◽  
Vol 77 (OCE4) ◽  
Author(s):  
P. Oustric ◽  
G. Finlayson ◽  
C. Gibbons ◽  
J. Blundell
Keyword(s):  
Systematic Review ◽  
Weight Management ◽  
Food Reward

scholarly journals The Joint Log-Lift Task: A Social Foraging Paradigm

2021 ◽  
Vol 8 ◽  
Author(s):  
Jean-Loup Rault ◽  
Irene Camerlink ◽  
Sébastien Goumon ◽  
Roger Mundry ◽  
Marek Špinka
Keyword(s):  
Home Environment ◽  
Large Scale ◽  
Food Reward ◽  
Social Dynamics ◽  
Partner Choice ◽  
Social Foraging ◽  
Task Success ◽  
Sus Scrofa Domesticus ◽  
Lift Task

Behavioural cooperation is under intense research. Yet, popular experimental paradigms often employ artificial tasks, require training, or do not permit partner choice, possibly limiting their biological relevance. We developed the joint log-lift task, a social foraging paradigm in which animals have to jointly lift a log to each obtain a food reward. The task relies on an obligate strategy, meaning that the only way to benefit is to work jointly. We hypothesised that (1) animals learn to spontaneously solve the task, and that (2) kin and (3) more sociable individuals would engage more often together in the task and achieve greater success than non-kin and less sociable individuals, respectively. We presented the task to 8 groups of juvenile domestic pigs (Sus scrofa domesticus) in their home pen for 30 min daily. Over the course of 9 days, the pigs showed evidence of learning by progressively switching from individual to joint behaviours, leading to 68% (62 out of 91 pigs) spontaneously solving the task. Success was influenced by sociability, but not kinship. There were large differences in success among dyads, hinting at the possible role of social dynamics and inter-individual differences in the ability and/or motivation to solve the task. The joint log-lift task allows researchers to investigate spontaneous cooperative tendencies of individuals, dyads and groups in the home environment through ad libitum engagement with the apparatus. This ecologically relevant paradigm opens the way to investigate social foraging experimentally at large scale, by giving animals free choice about when and with whom to work jointly.

scholarly journals The Role of Response-Reward Correlation in Stimulus-Response Overshadowing

1983 ◽  
Vol 35 (1b) ◽  
pp. 53-65 ◽  
Author(s):  
Roger M. Tarpy ◽  
Stephen E. G. Lea ◽  
Marie Midgley
Keyword(s):  
Food Reward ◽  
Response Rate ◽  
Food Delivery ◽  
Group Differences ◽  
Theory Approach ◽  
Lever Response ◽  
Stimulus Response ◽  
Lever Pressing ◽  
Fourth Experiment

Rats pressed levers for food reward which was delivered, when appropriate, 0·4 s after the response. For one group, the delay interval was filled by a light cue; for the other group, the same number of lights was given but they were not correlated with food delivery. In Experiment I, all lever presses were reinforced and there were no differences in response rate between groups. In Experiments II and III, lever pressing was rewarded according to a VI and VR schedule respectively. Group differences were observed in Experiment II but they disappeared in Experiment III. The results of Experiments I and II show that a reward-related stimulus does not overshadow a lever response unless the stimulus is a better predictor of reward. Differences in salience or competition from sign-tracking behaviors were ruled out as causes of this phenomenon. Experiment III demonstrated, however, that a weak response-reward correlation is not a sufficient condition for the overshadowing effect. A fourth experiment replicated the results of Experiment III using naive animals. The results of these last two experiments are not consistent with an information theory approach unless (a) a response-units concept is adopted or (b) the cue involved in overshadowing is not the pre-food light but the end of a temporal interval, whose salience is enhanced by the light.

scholarly journals Assessing the Role of Ghrelin and the Enzyme Ghrelin O-acyltransferase (GOAT) System in Food Reward, Food Motivation, and Binge Eating Behavior

2021 ◽  
pp. 105847
Author(s):  
Emanuela Micioni Di Bonaventura ◽  
Luca Botticelli ◽  
Fabio Del Bello ◽  
Gianfabio Giorgioni ◽  
Alessandro Piergentili ◽  
...  
Keyword(s):  
Binge Eating ◽  
Eating Behavior ◽  
Food Reward ◽  
Food Motivation

scholarly journals Ghrelin, Appetite Regulation, and Food Reward: Interaction with Chronic Stress

2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Yolanda Diz-Chaves
Keyword(s):  
Chronic Stress ◽  
Energy Homeostasis ◽  
Food Reward ◽  
Corticotropin Releasing Factor ◽  
Appetite Regulation ◽  
Compelling Evidence ◽  
Contributing Factors ◽  
Factor System ◽  
Developed World

Obesity has become one of the leading causes of illness and mortality in the developed world. Preclinical and clinical data provide compelling evidence for ghrelin as a relevant regulator of appetite, food intake, and energy homeostasis. In addition, ghrelin has recently emerged as one of the major contributing factors to reward-driven feeding that can override the state of satiation. The corticotropin-releasing-factor system is also directly implicated in the regulation of energy balance and may participate in the pathophysiology of obesity and eating disorders. This paper focuses on the role of ghrelin in the regulation of appetite, on its possible role as a hedonic signal involved in food reward, and on its interaction with the corticotropin-releasing-factor system and chronic stress.

scholarly journals Visibility and attractiveness of Fritillaria (Liliaceae) flowers to potential pollinators

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Katarzyna Roguz ◽  
Laurence Hill ◽  
Sebastian Koethe ◽  
Klaus Lunau ◽  
Agata Roguz ◽  
...  
Keyword(s):  
Food Reward ◽  
Potential Role ◽  
Flower Colour ◽  
Floral Traits ◽  
Nectar Guides ◽  
Flower Colours ◽  
Visual Attraction ◽  
Floral Characters ◽  
Plant Pollinator

AbstractVisual floral characters play an important role in shaping plant-pollinator interactions. The genus Fritillaria L. (Liliaceae), comprising approximately 140 species, is described as displaying a remarkable variety of flower colours and sizes. Despite this variation in visual floral traits of fritillaries, little is known about the potential role of these features in shaping plant-pollinator interactions. Here, we seek to clarify the role of visual attraction in species offering a robust food reward for pollinators early in the spring, which is the case for Fritillaria. We also searched for potential tendencies in the evolution of floral traits crucial for plant-pollinator communication. The generality of species with green and purple flowers may indicate an influence of environmental factors other than pollinators. The flowers of the studied species seem to be visible but not very visually attractive to potential pollinators. The food rewards are hidden within the nodding perianth, and both traits are conserved among fritillaries. Additionally, visual floral traits are not good predictors of nectar properties. When in the flowers, pollinators are navigated by nectar guides in the form of contrasting nectary area colouration. Flower colour does not serve as a phenotypic filter against illegitimate pollinators—red and orange bird-pollinated fritillaries are visible to bees.

scholarly journals Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Caesar M Hernandez ◽  
Caitlin A Orsini ◽  
Chase C Labiste ◽  
Alexa-Rae Wheeler ◽  
Tyler W Ten Eyck ◽  
...  
Keyword(s):  
Choice Behavior ◽  
Food Reward ◽  
Basolateral Amygdala ◽  
Intertemporal Choice ◽  
Intertrial Interval ◽  
Behavior Changes ◽  
Impulsive Choice ◽  
Aged Rats ◽  
Time Points

Across species, aging is associated with an increased ability to choose delayed over immediate gratification. These experiments used young and aged rats to test the role of the basolateral amygdala (BLA) in intertemporal decision making. An optogenetic approach was used to inactivate the BLA in young and aged rats at discrete time points during choices between levers that yielded a small, immediate vs. a large, delayed food reward. BLA inactivation just prior to decisions attenuated impulsive choice in both young and aged rats. In contrast, inactivation during receipt of the small, immediate reward increased impulsive choice in young rats but had no effect in aged rats. BLA inactivation during the delay or intertrial interval had no effect at either age. These data demonstrate that the BLA plays multiple, temporally distinct roles during intertemporal choice, and show that the contribution of BLA to choice behavior changes across the lifespan.

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