CCK-8 and PGE1: central effects on circadian body temperature and activity rhythms in rats

2004 ◽  
Vol 81 (4) ◽  
pp. 615-621 ◽  
Author(s):  
Zoltán Szelényi ◽  
Zoltán Hummel ◽  
Miklós Székely ◽  
Erika Pétervári
2019 ◽  
Vol 20 (8) ◽  
pp. 1988 ◽  
Author(s):  
Tadahiro Goda ◽  
Fumika N. Hamada

Human body temperature increases during wakefulness and decreases during sleep. The body temperature rhythm (BTR) is a robust output of the circadian clock and is fundamental for maintaining homeostasis, such as generating metabolic energy and sleep, as well as entraining peripheral clocks in mammals. However, the mechanisms that regulate BTR are largely unknown. Drosophila are ectotherms, and their body temperatures are close to ambient temperature; therefore, flies select a preferred environmental temperature to set their body temperature. We identified a novel circadian output, the temperature preference rhythm (TPR), in which the preferred temperature in flies increases during the day and decreases at night. TPR, thereby, produces a daily BTR. We found that fly TPR shares many features with mammalian BTR. We demonstrated that diuretic hormone 31 receptor (DH31R) mediates Drosophila TPR and that the closest mouse homolog of DH31R, calcitonin receptor (Calcr), is essential for mice BTR. Importantly, both TPR and BTR are regulated in a distinct manner from locomotor activity rhythms, and neither DH31R nor Calcr regulates locomotor activity rhythms. Our findings suggest that DH31R/Calcr is an ancient and specific mediator of BTR. Thus, understanding fly TPR will provide fundamental insights into the molecular and neural mechanisms that control BTR in mammals.


Oecologia ◽  
1999 ◽  
Vol 119 (4) ◽  
pp. 484-492 ◽  
Author(s):  
R. Elvert ◽  
N. Kronfeld ◽  
T. Dayan ◽  
A. Haim ◽  
N. Zisapel ◽  
...  

2011 ◽  
Vol 23 (3) ◽  
pp. 165-173 ◽  
Author(s):  
Karen M. von Deneen ◽  
Qin Wei ◽  
Liu Peng ◽  
Dong Ming Hao ◽  
Chen Peng ◽  
...  

1994 ◽  
Vol 72 (3) ◽  
pp. 572-574 ◽  
Author(s):  
Douglas W. Smith ◽  
Thomas D. Drummer ◽  
Rolf O. Peterson

Bovet claims that Smith et al. (D.W. Smith, R.O. Peterson, T.D. Drummer, and D.S. Sheputis, 1991. Can. J. Zool. 69: 2178–2182) and Dyck and MacArthur (A.P. Dyck and R.A. MacArthur, 1992. Can. J. Zool. 70: 1668–1672) analyzed their data on activity and body temperature of beavers (Castor canadensis) incorrectly because they ignored the likelihood that northern beavers in winter have activity rhythms with periods >24 h. The analysis by Smith et al. was in fact appropriate for demonstrating seasonal changes in body temperature and its correlation with activity. These are important issues because researchers have obtained conflicting results and because seasonal changes in activity and body temperature have implications for colony energetics in the context of food-hoarding behavior and social organization.


2001 ◽  
Vol 31 (3) ◽  
pp. 161-170 ◽  
Author(s):  
H Almirall ◽  
V Bautista ◽  
A Sánchez-Bahillo ◽  
M Trinidad-Herrero

1995 ◽  
Vol 702 (1-2) ◽  
pp. 173-180 ◽  
Author(s):  
Emmanuelle Goujon ◽  
Patricia Parnet ◽  
Sandrine Cremona ◽  
Robert Dantzer

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