scholarly journals The impact of folic acid supplementation on gestational and long term health: Critical temporal windows, benefits and risks

2017 ◽  
Vol 2 (6) ◽  
pp. 315-332 ◽  
Author(s):  
Carla Silva ◽  
Elisa Keating ◽  
Elisabete Pinto
Keyword(s):  
Folic Acid ◽  
Folic Acid Supplementation ◽  
Acid Supplementation ◽  
The Impact ◽  
Temporal Windows

scholarly journals The impact of antenatal care, iron–folic acid supplementation and tetanus toxoid vaccination during pregnancy on child mortality in Bangladesh

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0187090 ◽  
Author(s):  
Tanvir Abir ◽  
Felix Akpojene Ogbo ◽  
Garry John Stevens ◽  
Andrew Nicolas Page ◽  
Abul Hasnat Milton ◽  
...  
Keyword(s):  
Folic Acid ◽  
Antenatal Care ◽  
Child Mortality ◽  
Tetanus Toxoid ◽  
Folic Acid Supplementation ◽  
Acid Supplementation ◽  
Iron Folic Acid Supplementation ◽  
Iron Folic Acid ◽  
The Impact

scholarly journals The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen Folic Acid Supplementation Trial (AFAST)

2018 ◽  
Vol 47 (3) ◽  
pp. 928-937 ◽  
Author(s):  
Rebecca C Richmond ◽  
Gemma C Sharp ◽  
Georgia Herbert ◽  
Charlotte Atkinson ◽  
Caroline Taylor ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Folic Acid ◽  
Folic Acid Supplementation ◽  
Acid Supplementation ◽  
Long Term Impact ◽  
In Pregnancy

Effect of Folic Acid Supplementation on Seizure Control in Epileptic Children Receiving Long Term Antiepileptic Therapy

2018 ◽  
Vol 85 (7) ◽  
pp. 493-497 ◽  
Author(s):  
Bindu Deopa ◽  
Manish Parakh ◽  
Pawan Dara ◽  
Vikas Payal ◽  
Kapil Chordiya ◽  
...  
Keyword(s):  
Folic Acid ◽  
Seizure Control ◽  
Folic Acid Supplementation ◽  
Acid Supplementation ◽  
Antiepileptic Therapy ◽  
Epileptic Children

scholarly journals Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers

2018 ◽  
Vol 120 (10) ◽  
pp. 1122-1130 ◽  
Author(s):  
Binyan Wang ◽  
Hongxu Wu ◽  
Youbao Li ◽  
Qianyun Ban ◽  
Xiao Huang ◽  
...  
Keyword(s):  
Folic Acid ◽  
Low Dose ◽  
Methylenetetrahydrofolate Reductase ◽  
Smoking Status ◽  
Folic Acid Supplementation ◽  
Major Effect ◽  
Acid Supplementation ◽  
Total Homocysteine ◽  
Using Data

AbstractWe sought to examine the potential modifiers in the association between long-term low-dose folic acid supplementation and the reduction of serum total homocysteine (tHcy) among hypertensive patients, using data from the China Stroke Primary Prevention Trial (CSPPT). This analysis included 16 867 participants who had complete data on tHcy measurements at both the baseline and exit visit. After a median treatment period of 4·5 years, folic acid treatment significantly reduced the tHcy levels by 1·6 μmol/l (95 % CI 1·4, 1·8). More importantly, after adjustment for baseline tHcy and other important covariates, a greater degree of tHcy reduction was observed in certain subgroups: males, the methylenetetrahydrofolate reductase (MTHFR) 677TT genotype, higher baseline tHcy levels (≥12·5 (median) v. <12·5 μmol/l), lower folate levels (<8·0 (median) v. ≥8·0 ng/ml), estimated glomerular filtration rate (eGFR) <60 ml/min per 1·73 m2 (v. 60–<90 and ≥90 ml/min per 1·73 m2), ever smokers and concomitant use of diuretics (P for all interactions <0·05). The degree of tHcy reduction associated with long-term folic acid supplementation can be significantly affected by sex, MTHFR C677T genotypes, baseline folate, tHcy, eGFR levels and smoking status.

The impact of folate status and folic acid supplementation on the micronucleus frequency in human erythrocytes

2006 ◽  
Vol 603 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Lilianne Abramsson-Zetterberg ◽  
Louise J.K. Durling ◽  
Fan Yang-Wallentin ◽  
Elisabet Rytter ◽  
Bengt Vessby
Keyword(s):  
Folic Acid ◽  
Folic Acid Supplementation ◽  
Human Erythrocytes ◽  
Acid Supplementation ◽  
Folate Status ◽  
Micronucleus Frequency ◽  
The Impact
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