17. Red spot diagnosis – Extramedullary haemopoiesis within a benign vascular lesion, with dysplastic megakaryocytes

Pathology ◽  
2019 ◽  
Vol 51 ◽  
pp. S152
Author(s):  
N. Prosser ◽  
H. Stern ◽  
S. Larsen ◽  
W. Cooper ◽  
E. Robbins ◽  
...  
Keyword(s):  
Vascular Lesion ◽  
Extramedullary Haemopoiesis

Oxidative Stress and Atherosclerosis: Its Relationship to Growth Factors, Thrombus Formation and Therapeutic Approaches

1999 ◽  
Vol 82 (S 01) ◽  
pp. 32-37 ◽  
Author(s):  
Karlheinz Peter ◽  
Wolfgang Kübler ◽  
Johannes Ruef ◽  
Thomas K. Nordt ◽  
Marschall S. Runge ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Growth Factors ◽  
Vessel Wall ◽  
Inflammatory Responses ◽  
Plaque Rupture ◽  
Thrombus Formation ◽  
Vascular Lesion ◽  
Coagulation System ◽  
Therapeutic Approaches ◽  
Causative Relationship

SummaryThe initiating event of atherogenesis is thought to be an injury to the vessel wall resulting in endothelial dysfunction. This is followed by key features of atherosclerotic plaque formation such as inflammatory responses, cell proliferation and remodeling of the vasculature, finally leading to vascular lesion formation, plaque rupture, thrombosis and tissue infarction. A causative relationship exists between these events and oxidative stress in the vessel wall. Besides leukocytes, vascular cells are a potent source of oxygen-derived free radicals. Oxidants exert mitogenic effects that are partially mediated through generation of growth factors. Mitogens, on the other hand, are potent stimulators of oxidant generation, indicating a putative self-perpetuating mechanism of atherogenesis. Oxidants influence the balance of the coagulation system towards platelet aggregation and thrombus formation. Therapeutic approaches by means of antioxidants are promising in both experimental and clinical designs. However, additional clinical trials are necessary to assess the role of antioxidants in cardiovascular disease.

PERAN AIR REBUSAN DAUN SALAM (SYZGIUM POLYANTHUM) DALAM MENURUNKAN KADAR ASAM URAT

2016 ◽  
Vol 5 (2) ◽  
pp. 83-91
Author(s):  
Miftafu Darussalam ◽  
Dwi Kartika Rukmi
Keyword(s):  
Uric Acid ◽  
Vascular Inflammation ◽  
Vascular Lesion ◽  
Wilcoxon Test ◽  
Test Time ◽  
Control Group ◽  
Target Area ◽  
Bioactive Substances ◽  
Control Group Design ◽  
Boiled Water

Background: Uric acid is a final product or a waste that is resulted from the metabolism of purines. A high level of uric acid (hyperuricemia) will cause several health problems, such as vascular inflammation, smooth muscle proliferation, and vascular lesion in kidneys. The syzygium polyanthum leaves contain bioactive substances that may affect the level of uric acid in blood. Objective: This study aimed to determine the influence of boiled water of syzygium polyanthum leaves to the changes of uric acid levels in the target area of Puskesmas Pandak 1 Bantul. Methods: This study employed pre- and post-test without control group design. The population consisted of all patients with hyperuricemia in the target area of Puskesmas Pandak 1 Bantul. Sample was selected with a concecutive sampling, gaining a total number of 24 respondents. Data were analyzed with the Wilcoxon test. The dose of boiled water of syzygium polyanthum leaves intake was 0.36g/ KgBW, once a day for 14 days. Result: This research showed that the boiled water of syzygium polyanthum leaves decreased hyperuricemia (uric acid levels), along with the significancy value of 0.009 (p <0.05). At the pre-test time, the average level of uric acid reached 7.279 mg/dl, and after the treatment, it decreased to 6.76 mg/dl. Conclusion: This study has established evidence that the boiled water of syzygium polyanthum leaves is able to decrease hyperuricemia (uric acid level in blood). Keywords: syzygium polyanthum, boiled water of syzygium polyanthum leaves, hyperuricemia

Glomangiopericytoma of the sphenoethmoid complex

2020 ◽  
Vol 13 (12) ◽  
pp. e236048
Author(s):  
Larry Shemen ◽  
Wayne Yan ◽  
Adnan Hasanovic ◽  
Jiankun Tong
Keyword(s):  
Surgical Resection ◽  
World Literature ◽  
Vascular Lesion ◽  
Common Type ◽  
Optimal Treatment ◽  
Rare Tumour ◽  
Complete Surgical Resection ◽  
The World

Sinonasal glomangiopericytoma is a rare sinonasal tumour accounting for less than. 5% of all sinonasal tumours. This tumour often presents as another, more common type of vascular lesion and is similarly prone to haemorrhage. The optimal treatment includes complete surgical resection. We, herein, present two such cases adding to the world literature of this rare tumour.

A rare case of intra-uterine blood transfusion for fetal anemia caused by a giant placental chorioangioma

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Shira Raviv ◽  
Alon Shrim ◽  
Julia Eidel ◽  
Yoav Yinon ◽  
Boaz Weiz ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Peak Systolic Velocity ◽  
Fetal Hemoglobin ◽  
Vascular Lesion ◽  
Hemoglobin Level ◽  
Fetal Anemia ◽  
Fetal Heart Rate Monitoring ◽  
Fetal Complications ◽  
Tumor Like Lesions ◽  
Fetal Hemoglobin Level

Abstract Objectives Chorioangiomas (CAs) are the most frequent tumor-like-lesions of the placenta. Giant CAs (more than 4–5 cm in diameter) is rare and may result in severe maternal fetal complications. Case presentation A 38-year-old multigravida presented at 31 weeks’ gestation with contractions. Upon evaluation, contractions were spontaneously ceased, and the cervix was closed. Ultrasound examination revealed a single viable fetus, polyhydramnios and a 75 x 48 x 82 mm vascular lesion located on the placental surface near the cord insertion. Doppler assessment was suggestive of fetal anemia with middle cerebral artery-peak systolic velocity (MCA-PSV) 1.8 MoM’s. Fetal heart rate monitoring and biophysical scores were reassuring. Following betamethasone fetal cord sampling that revealed fetal hemoglobin level of 8.8 g/dL, 57 cc of blood was transfused resulting in final hemoglobin level of 14.3 g/dL measured prior to needle extraction. MCA-PSV was normalized immediately after the procedure, however aggravated at the following day with MCA-PSV 65 cm/s (1.46 MoM’s). No other intervention was taken and MCA-PSV continued to fluctuate from slight to severe anemia spontaneously over a period of two weeks. At 34 gestational weeks, the women delivered a healthy baby. Fetal hemoglobin level at delivery was 21 g/dL. Conclusions Fetal blood transfusion is a reasonable treatment for fetal anemia in cases of giant chorioangiomas. Following transfusion, MCA-PSV may act unexpectedly reflecting various mechanisms affecting the flow.

Can the Human Tail Cause Arteriovenous Hemangioma?

2020 ◽  
pp. 1-5
Author(s):  
Pinar Aydin Ozturk ◽  
Seyhmus Kaya
Keyword(s):  
Skin Color ◽  
Squamous Epithelium ◽  
Normal Skin ◽  
Distal Portion ◽  
Vascular Lesion ◽  
Pathological Findings ◽  
Lumbosacral Region ◽  
Fibrous Stroma ◽  
Human Tail ◽  
Vascular Structures

<b><i>Introduction:</i></b> “Human tail” is a congenital, benign anomaly in which a protrusion in the lumbosacrococcygeal caudal region is covered with skin. Arteriovenous hemangioma is a benign vascular lesion that may be congenital or acquired. We present a case in which a human tail was present with pathological findings of arteriovenous hemangioma. <b><i>Case Report:</i></b> A 6-month-old girl was born with a curved tail-shaped protrusion along her waistline. The distal portion was purple and had a solid consistency; the proximal portion was of normal skin color and had a soft consistency. No other abnormality was observed in the spinal area. Microscopic examination revealed congested, proliferated vascular structures in the fibrous stroma distally located under the multilayered squamous epithelium. In the proximal area, mature lipomatous tissue was observed. The lesion was diagnosed as arteriovenous hemangioma. <b><i>Conclusion:</i></b> Our patient presented with the classic “human tail” appearance at an early age and in the lumbosacral region. Because of the pathological findings, surgery for the congenital anomaly had to be performed with extra caution.

Stereotactic Aspiration of a Brain Stem Hematoma

Neurosurgery ◽  
1983 ◽  
Vol 13 (2) ◽  
pp. 204-207 ◽  
Author(s):  
Robert M. Beatty ◽  
Nicholas T. Zervas
Keyword(s):  
Medical Student ◽  
Brain Stem ◽  
Ct Scanning ◽  
Vascular Lesion ◽  
Venous Angioma ◽  
Stereotactic Aspiration ◽  
Computed Tomographic

Abstract A medical student developed a progressive mesencephalic lesion found to be cystic in nature by computed tomographic (CT) scanning. Stereotactic aspiration of a pontomesencephalic hematoma was carried out twice, and the patient recovered. Angiography and CT scanning demonstrated a vascular lesion compatible with a venous angioma.

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