Papillary thyroid carcinoma with diffuse sclerosing variant features, arising in a likely thyroglossal duct remnant in a 12-year-old female

Pathology ◽  
2017 ◽  
Vol 49 ◽  
pp. S88
Author(s):  
Adam Swalling ◽  
Nicholas Manton ◽  
Lynette Moore
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Papillary Thyroid ◽  
Thyroglossal Duct ◽  
Diffuse Sclerosing Variant ◽  
Thyroglossal Duct Remnant

scholarly journals Synchronous squamous cell carcinoma and papillary thyroid carcinoma arising from the thyroglossal duct remnant: Case report and a review of the literature

2020 ◽  
Vol 8 ◽  
pp. 2050313X2091784
Author(s):  
Marco Puccini ◽  
Nicolò Roffi ◽  
Valentina Pucci ◽  
Giacomo Fiacchini ◽  
Clara Ugolini ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Event ◽  
Papillary Thyroid ◽  
Review Of The Literature ◽  
Thyroglossal Duct ◽  
Thyroglossal Duct Remnant

Squamous cell carcinoma and papillary thyroid carcinoma simultaneously spreading from the thyroglossal duct remnant (TGDR) is a very rare event. The recognition of this condition allows a correct management and treatment, offering the best chances of cure to the patient. We describe the case of a 42-year-old woman who noticed a right-sided lump in her neck. An ultrasound scan confirmed multiple clusters of enlarged lymph nodes on the right side associated to a pre-hyoidal solid nodule. The thyroid gland was normal. Fine-needle aspiration cytology on two nodes revealed distinct metastases from squamous cell carcinoma and from papillary thyroid carcinoma. A careful screening for other head and neck tumors was negative. She underwent a Sistrunk procedure, total thyroidectomy and right lateral lymphadenectomy with en bloc jugular vein resection. On histology, a 2 cm papillary and a small squamous cell carcinoma of the TGDR were documented, with nodal metastases from both primaries. We report the overall management strategy, treatment and outcome at 26-month follow-up, and a review of the literature.

scholarly journals Diffuse sclerosing variant of papillary thyroid carcinoma: lack of BRAF mutation but occurrence of RET/PTC rearrangements

2007 ◽  
Vol 20 (7) ◽  
pp. 779-787 ◽  
Author(s):  
Sien-Yi Sheu ◽  
Suzan Schwertheim ◽  
Karl Worm ◽  
Florian Grabellus ◽  
Kurt Werner Schmid
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Braf Mutation ◽  
Papillary Thyroid ◽  
Diffuse Sclerosing Variant

scholarly journals Thyroglossal Duct Carcinoma with Concurrent Papillary Thyroid Carcinoma: A Case Report

2020 ◽  
Vol 35 (1) ◽  
pp. 63-65
Author(s):  
Anna Claudine Lahoz ◽  
Precious Eunice Grullo ◽  
Ryner Jose Carrillo
Keyword(s):  
Case Report ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Preoperative Assessment ◽  
University Hospital ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Duct Carcinoma ◽  
Thyroglossal Duct ◽  
Thyroglossal Duct Carcinoma

ABSTRACT Objective: To report a case of thyroglossal duct carcinoma with concurrent papillary thyroid carcinoma Methods: Design: Case Report Setting: Tertiary National University Hospital Patient: One Results: A 46-year-old woman was diagnosed with thyroglossal duct carcinoma after undergoing a Sistrunk procedure. Due to presence of thyroid nodules, the patient underwent second stage thyroidectomy with central neck dissection which revealed papillary thyroid carcinoma. Conclusion: Thyroglossal duct carcinomas are rare entities and there is no current consensus regarding their management. Difficulties arise in the diagnosis of these tumors as they present similarly to benign thyroglossal duct cysts. Most cases are diagnosed postoperatively. Proper preoperative assessment including head and neck examination, biopsy, and radiologic imaging is necessary to recognize patients who could benefit from more aggressive management. Keywords: thyroglossal carcinoma; thyroglossal duct cyst; papillary thyroid carcinoma

Two Cases of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma

2008 ◽  
Vol 23 (6) ◽  
pp. 430
Author(s):  
Hee Kwan Won ◽  
Myoung Jun Lee ◽  
Joo Ho Park ◽  
In Girl Song ◽  
Go Eun Lee ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Papillary Thyroid ◽  
Diffuse Sclerosing Variant
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