Multiple guide stars optimization in conjugate adaptive optics for deep tissue imaging

2020 ◽  
Vol 459 ◽  
pp. 124891
Author(s):  
Chenxue Wu ◽  
Jiajia Chen ◽  
Biwei Zhang ◽  
Yao Zheng ◽  
Xinpei Zhu ◽  
...  
Keyword(s):  
Adaptive Optics ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Deep Tissue Imaging

scholarly journals Overcoming the penetration depth limit in optical microscopy: Adaptive optics and wavefront shaping

2019 ◽  
Vol 12 (04) ◽  
pp. 1930002 ◽  
Author(s):  
Cheolwoo Ahn ◽  
Byungjae Hwang ◽  
Kibum Nam ◽  
Hyungwon Jin ◽  
Taeseong Woo ◽  
...  
Keyword(s):  
High Resolution ◽  
Optical Microscopy ◽  
Adaptive Optics ◽  
Single Cells ◽  
Tissue Imaging ◽  
Future Research ◽  
Deep Tissue ◽  
Depth Limit ◽  
Deep Tissue Imaging ◽  
Wavefront Shaping

Despite the unique advantages of optical microscopy for molecular specific high resolution imaging of living structure in both space and time, current applications are mostly limited to research settings. This is due to the aberrations and multiple scattering that is induced by the inhomogeneous refractive boundaries that are inherent to biological systems. However, recent developments in adaptive optics and wavefront shaping have shown that high resolution optical imaging is not fundamentally limited only to the observation of single cells, but can be significantly enhanced to realize deep tissue imaging. To provide insight into how these two closely related fields can expand the limits of bio imaging, we review the recent progresses in their performance and applicable range of studies as well as potential future research directions to push the limits of deep tissue imaging.

Responsive optical probes for deep-tissue imaging: Photoacoustics and second near-infrared fluorescence

2021 ◽  
Vol 173 ◽  
pp. 141-163
Author(s):  
Fei Ding ◽  
Jing Feng ◽  
Xueli Zhang ◽  
Jielin Sun ◽  
Chunhai Fan ◽  
...  
Keyword(s):  
Near Infrared ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Optical Probes ◽  
Near Infrared Fluorescence ◽  
Deep Tissue Imaging

scholarly journals Slow light for deep tissue imaging with ultrasound modulation

2012 ◽  
Vol 100 (13) ◽  
pp. 131102 ◽  
Author(s):  
Huiliang Zhang ◽  
Mahmood Sabooni ◽  
Lars Rippe ◽  
Chulhong Kim ◽  
Stefan Kröll ◽  
...  
Keyword(s):  
Slow Light ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Deep Tissue Imaging ◽  
Ultrasound Modulation

scholarly journals Transgenic mice: beyond the knockout

2011 ◽  
Vol 300 (2) ◽  
pp. F291-F300 ◽  
Author(s):  
R. Lance Miller
Keyword(s):  
Transgenic Mice ◽  
Fluorescent Proteins ◽  
Primary Cultures ◽  
Cell Lineage ◽  
Tissue Imaging ◽  
Cell Type ◽  
Deep Tissue ◽  
Pure Cell ◽  
Deep Tissue Imaging ◽  
Tremendous Impact

Transgenic mice have had a tremendous impact on biomedical research. Most researchers are familiar with transgenic mice that carry Cre recombinase (Cre) and how they are used to create conditional knockouts. However, some researchers are less familiar with many of the other types of transgenic mice and their applications. For example, transgenic mice can be used to study biochemical and molecular pathways in primary cultures and cell suspensions derived from transgenic mice, cell-cell interactions using multiple fluorescent proteins in the same mouse, and the cell cycle in real time and in the whole animal, and they can be used to perform deep tissue imaging in the whole animal, follow cell lineage during development and disease, and isolate large quantities of a pure cell type directly from organs. These novel transgenic mice and their applications provide the means for studying of molecular and biochemical events in the whole animal that was previously limited to cell cultures. In conclusion, transgenic mice are not just for generating knockouts.

Designing Upconversion Nanocrystals Capable of 745 nm Sensitization and 803 nm Emission for Deep-Tissue Imaging

2016 ◽  
Vol 22 (31) ◽  
pp. 10801-10807 ◽  
Author(s):  
Liangliang Liang ◽  
Xiaoji Xie ◽  
Daniel Teh Boon Loong ◽  
Angelo Homayoun All ◽  
Ling Huang ◽  
...  
Keyword(s):  
Tissue Imaging ◽  
Deep Tissue ◽  
Upconversion Nanocrystals ◽  
Deep Tissue Imaging

scholarly journals Near-infrared probe-based confocal microendoscope for deep-tissue imaging

2018 ◽  
Vol 9 (10) ◽  
pp. 5011 ◽  
Author(s):  
Jiafu Wang ◽  
Hua Li ◽  
Geng Tian ◽  
Yong Deng ◽  
Qian Liu ◽  
...  
Keyword(s):  
Near Infrared ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Deep Tissue Imaging

The one-pot synthesis of core/shell/shell CdTe/CdSe/ZnSe quantum dots in aqueous media for in vivo deep tissue imaging

2011 ◽  
Vol 21 (9) ◽  
pp. 2877 ◽  
Author(s):  
Shohei Taniguchi ◽  
Mark Green ◽  
Sarwat B. Rizvi ◽  
Alexander Seifalian
Keyword(s):  
Quantum Dots ◽  
Aqueous Media ◽  
Tissue Imaging ◽  
Core Shell ◽  
Deep Tissue ◽  
One Pot ◽  
One Pot Synthesis ◽  
Deep Tissue Imaging ◽  
The One
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