Deep-red polymer dots with bright two-photon fluorescence and high biocompatibility for in vivo mouse brain imaging

2017 ◽  
Vol 399 ◽  
pp. 120-126 ◽  
Author(s):  
Nuernisha Alifu ◽  
Zezhou Sun ◽  
Abudureheman Zebibula ◽  
Zhenggang Zhu ◽  
Xinyuan Zhao ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Mouse Brain ◽  
Two Photon ◽  
Polymer Dots ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

In vivo brain imaging using a portable 39?gram two-photon fluorescence microendoscope

2005 ◽  
Vol 30 (17) ◽  
pp. 2272 ◽  
Author(s):  
Benjamin A. Flusberg ◽  
Juergen C. Jung ◽  
Eric D. Cocker ◽  
Erik P. Anderson ◽  
Mark J. Schnitzer
Keyword(s):  
Brain Imaging ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

NIR‐II Excitable Conjugated Polymer Dots with Bright NIR‐I Emission for Deep In Vivo Two‐Photon Brain Imaging Through Intact Skull

2019 ◽  
Vol 29 (15) ◽  
pp. 1808365 ◽  
Author(s):  
Shaowei Wang ◽  
Jie Liu ◽  
Guangxue Feng ◽  
Lai Guan Ng ◽  
Bin Liu
Keyword(s):  
Brain Imaging ◽  
Conjugated Polymer ◽  
Two Photon ◽  
Polymer Dots

Silole-Based Red Fluorescent Organic Dots for Bright Two-Photon Fluorescence In vitro Cell and In vivo Blood Vessel Imaging

Small ◽  
2015 ◽  
Vol 12 (6) ◽  
pp. 782-792 ◽  
Author(s):  
Bin Chen ◽  
Guangxue Feng ◽  
Bairong He ◽  
Chiching Goh ◽  
Shidang Xu ◽  
...  
Keyword(s):  
Blood Vessel ◽  
Two Photon ◽  
Vessel Imaging ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

scholarly journals Two-Photon Microscopy Allows Imaging and Characterization of Cochlear Microvasculature In Vivo

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Friedrich Ihler ◽  
Mattis Bertlich ◽  
Bernhard Weiss ◽  
Steffen Dietzel ◽  
Martin Canis
Keyword(s):  
Fluorescence Microscopy ◽  
Inner Ear ◽  
Ex Vivo ◽  
Small Scale ◽  
Published Data ◽  
Cochlear Blood Flow ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Impairment of cochlear blood flow has been discussed as factor in the pathophysiology of various inner ear disorders. However, the microscopic study of cochlear microcirculation is limited due to small scale and anatomical constraints. Here, two-photon fluorescence microscopy is applied to visualize cochlear microvessels. Guinea pigs were injected with Fluorescein isothiocyanate- or Texas red-dextrane as plasma marker. Intravital microscopy was performed in four animals and explanted cochleae from four animals were studied. The vascular architecture of the cochlea was visualized up to a depth of90.0±22.7 μm. Imaging yielded a mean contrast-to-noise ratio (CNR) of3.3±1.7. Mean diameter in vivo was16.5±6.0 μm for arterioles and8.0±2.4 μm for capillaries. In explanted cochleae, the diameter of radiating arterioles and capillaries was measured with12.2±1.6 μm and6.6±1.0 μm, respectively. The difference between capillaries and arterioles was statistically significant in both experimental setups (P<0.001andP=0.022, two-way ANOVA). Measured vessel diameters in vivo and ex vivo were in agreement with published data. We conclude that two-photon fluorescence microscopy allows the investigation of cochlear microvessels and is potentially a valuable tool for inner ear research.

scholarly journals Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging

2015 ◽  
Vol 6 (11) ◽  
pp. 4483 ◽  
Author(s):  
Anna Letizia Allegra Mascaro ◽  
Irene Costantini ◽  
Emilia Margoni ◽  
Giulio Iannello ◽  
Alessandro Bria ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Near Infrared ◽  
Infrared Reflectance ◽  
Label Free ◽  
Near Infrared Reflectance ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Reflectance Microscopy ◽  
Photon Fluorescence

Unprecedentedly High Tissue Penetration Capability of Co-Assembled Nanosystems for Two-Photon Fluorescence Imaging In Vivo

2015 ◽  
Vol 3 (5) ◽  
pp. 646-651 ◽  
Author(s):  
Pei-Pei Yang ◽  
Yang Yang ◽  
Yu-Juan Gao ◽  
Yi Wang ◽  
Ju-Chen Zhang ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Tissue Penetration ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence
Sign in / Sign up

Export Citation Format

Share Document