Delayed bone healing by collagen membrane in early phase of 4 weeks

2018 ◽  
Vol 126 (6) ◽  
pp. 469-476
Author(s):  
Jungtae Lee ◽  
Dajung Lee ◽  
Seo-Eun Oh ◽  
Kyeong-Mee Park ◽  
Kyung-Seok Hu ◽  
...  
Keyword(s):  
Bone Healing ◽  
Early Phase ◽  
Collagen Membrane ◽  
Delayed Bone Healing

Macrophages accumulate in the early phase of tendon–bone healing

2005 ◽  
Vol 23 (6) ◽  
pp. 1425-1432 ◽  
Author(s):  
S KAWAMURA ◽  
L YING ◽  
H KIM ◽  
C DYNYBIL ◽  
S RODEO
Keyword(s):  
Bone Healing ◽  
Early Phase

scholarly journals Bone Regeneration Assessment of Polycaprolactone Membrane on Critical-Size Defects in Rat Calvaria

Membranes ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 124
Author(s):  
Ana Paula Farnezi Bassi ◽  
Vinícius Ferreira Bizelli ◽  
Tamires Mello Francatti ◽  
Ana Carulina Rezende de Moares Ferreira ◽  
Járede Carvalho Pereira ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Healing ◽  
Inflammatory Responses ◽  
Blood Clot ◽  
Healing Process ◽  
Male Rats ◽  
Control Group ◽  
Collagen Membrane ◽  
Large Area ◽  
Rat Calvaria

Biomaterials for use in guided bone regeneration (GBR) are constantly being investigated and developed to improve clinical outcomes. The present study aimed to comparatively evaluate the biological performance of different membranes during the bone healing process of 8 mm critical defects in rat calvaria in order to assess their influence on the quality of the newly formed bone. Seventy-two adult male rats were divided into three experimental groups (n = 24) based on the membranes used: the CG—membrane-free control group (only blood clot, negative control), BG—porcine collagen membrane group (Bio-Guide®, positive control), and the PCL—polycaprolactone (enriched with 5% hydroxyapatite) membrane group (experimental group). Histological and histometric analyses were performed at 7, 15, 30, and 60 days postoperatively. The quantitative data were analyzed by two-way ANOVA and Tukey’s test (p < 0.05). At 7 and 15 days, the inflammatory responses in the BG and PCL groups were significantly different (p < 0.05). The PCL group, at 15 days, showed a large area of newly formed bone. At 30 and 60 days postoperatively, the PCL and BG groups exhibited similar bone healing, including some specimens showing complete closure of the critical defect (p = 0.799). Thus, the PCL membrane was biocompatible, and has the potential to help with GBR procedures.

Mechanical induction of critically delayed bone healing in sheep: Radiological and biomechanical results

2008 ◽  
Vol 41 (14) ◽  
pp. 3066-3072 ◽  
Author(s):  
Hanna Schell ◽  
Mark S. Thompson ◽  
Hermann J. Bail ◽  
Jan-Erik Hoffmann ◽  
Alexander Schill ◽  
...  
Keyword(s):  
Bone Healing ◽  
Delayed Bone Healing

Delayed bone healing following high tibial osteotomy related to increased implant stiffness in locked plating

Injury ◽  
2014 ◽  
Vol 45 (10) ◽  
pp. 1648-1652 ◽  
Author(s):  
Götz Röderer ◽  
Florian Gebhard ◽  
Lutz Duerselen ◽  
Anita Ignatius ◽  
Lutz Claes
Keyword(s):  
High Tibial Osteotomy ◽  
Bone Healing ◽  
Tibial Osteotomy ◽  
Locked Plating ◽  
Delayed Bone Healing

Insight into the Molecular Pathophysiology of Delayed Bone Healing in a Sheep Model

2010 ◽  
Vol 16 (1) ◽  
pp. 191-199 ◽  
Author(s):  
Jasmin Lienau ◽  
Katharina Schmidt-Bleek ◽  
Anja Peters ◽  
Hauke Weber ◽  
Hermann J. Bail ◽  
...  
Keyword(s):  
Bone Healing ◽  
Sheep Model ◽  
Molecular Pathophysiology ◽  
Insight Into ◽  
Delayed Bone Healing

scholarly journals Future Treatment Strategies for Delayed Bone Healing

2016 ◽  
Vol 24 (10) ◽  
pp. e134-e135 ◽  
Author(s):  
Katharina Schmidt-Bleek ◽  
Ralph Marcucio ◽  
Georg Duda
Keyword(s):  
Bone Healing ◽  
Treatment Strategies ◽  
Future Treatment ◽  
Delayed Bone Healing

scholarly journals Rodent animal models of delayed bone healing and non-union formation: a comprehensive review

2013 ◽  
Vol 26 ◽  
pp. 1-14 ◽  
Author(s):  
P Garcia ◽  
◽  
T Histing ◽  
JH Holstein ◽  
W Klein ◽  
...  
Keyword(s):  
Animal Models ◽  
Bone Healing ◽  
Union Formation ◽  
Comprehensive Review ◽  
Non Union ◽  
Delayed Bone Healing

scholarly journals Composite transcriptome assembly of RNA-seq data in a sheep model for delayed bone healing

BMC Genomics ◽  
2011 ◽  
Vol 12 (1) ◽  
Author(s):  
Marten Jäger ◽  
Claus-Eric Ott ◽  
Johannes Grünhagen ◽  
Jochen Hecht ◽  
Hanna Schell ◽  
...  
Keyword(s):  
Bone Healing ◽  
Transcriptome Assembly ◽  
Rna Seq ◽  
Sheep Model ◽  
Delayed Bone Healing
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