PRIMORDIAL ODONTOGENIC TUMOR-IMMUNOHISTOCHEMICAL STUDIES OF A RARE ENTITY

Author(s):  
A. Almazyad ◽  
C.-C. Li ◽  
I.J. Stojanov ◽  
S.-B. Woo
Reports ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 4
Author(s):  
Sawako Ono ◽  
Hotaka Kawai ◽  
Shintaro Sukegawa ◽  
Kiyofumi Takabatake ◽  
Keisuke Nakano ◽  
...  

Primordial odontogenic tumor (POT) is a rare odontogenic tumor characterized by a variably cellular loose fibrous tissue with areas similar to the dental papilla and covered by cuboidal to columnar epithelium. We herein report a case of POT in a 14-year-old boy. Computed tomography (CT) exhibited a round cavity with a defined cortical border circumscribing the tooth of the second molar. However, the gross finding was a solid mass, not a cyst. Histologically, the tumor consisted of dental papillalike myxoid connective tissue covered by columnar epithelium. Therefore, although the clinical diagnosis was dentigerous cyst (DC), we diagnosed POT based on histologic findings. Clinical findings of POT resemble DC, but the clinical behavior of POT is different to DC, such as cortical expansion and root resorption of teeth. Therefore, histological differentiation of POT from DC is critical for accurate diagnosis.


Author(s):  
Ankur Gupta ◽  
Ancy S. Sofia ◽  
Kanwar Sen

<p class="abstract">Extra skeletal Ewing’s sarcoma (EES) is a rare, rapidly growing, round cell malignant tumour that can develop in the soft tissue at any location. Involvement of the paranasal sinus is a very rare entity. Nearly 80% of patients are younger than 20 years. Diagnosis is made after histopathological examination, immunohistochemical studies and cytogenetic studies. Treatment includes a multidisciplinary approach with surgery as the first line followed by chemotherapy and radiotherapy.</p><p class="abstract"> </p>


2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Lucas Novaes Teixeira ◽  
Cristiane Furuse ◽  
Fabrício Passador Santos ◽  
Andresa Borges Soares ◽  
Eder Magno Ferreira de Oliveira ◽  
...  

Primordial odontogenic tumor (POT) is a benign mixed odontogenic tumor comprised of a loose connective tissue with a similar morphology with dental papilla and exhibiting in its periphery the presence of a columnar epithelium. POT occurs in young patients and typically is associated with an unerupted tooth, with the mandible being the main anatomic site of occurrence. The present manuscript is aimed at describing a new case of POT and reviewing the main biologic findings related to this odontogenic tumor.


2016 ◽  
Vol 74 (3) ◽  
pp. 547-551 ◽  
Author(s):  
Lee J. Slater ◽  
Liviu F. Eftimie ◽  
Alan S. Herford

2013 ◽  
Vol 2013 ◽  
pp. 1-7
Author(s):  
Ronell Bologna-Molina ◽  
Sirced Salazar-Rodríguez ◽  
Ana María Bedoya-Borella ◽  
Ramón Gil Carreón-Burciaga ◽  
Gabriel Tapia-Repetto ◽  
...  

Ameloblastic fibrodentinoma (AFD) is considered a mixed odontogenic tumor that is characterized by conserved epithelial and ectomesenchymal neoplastic components. AFD is composed of long narrow cords and islands of odontogenic epithelium; the epithelial strands lie in a myxoid cell-rich ectomesenchymal tissue with stellate-shaped fibroblasts that exhibit long slender cytoplasmic extensions that resemble dental papilla. The lesions show the presence of dysplastic dentin. Although AFD is a rare entity and its very existence is not completely accepted, based on the extent of histodifferentiation, it is considered to represent a stage between ameloblastic fibroma and ameloblastic fibroodontoma. This study aimed to provide a histopathological and immunohistochemical characterization of this infrequent tumor. A large panel of antibodies including amelogenin, Ck 19, calretinin, syndecan-1, E-cadherin, MSH2, histone H3, and Ki-67 was used to illustrate the nature of the tumor.


2018 ◽  
Vol 13 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Bianca Bravim Bomfim ◽  
Roberto Prado ◽  
Renato Kobler Sampaio ◽  
Danielle Castex Conde ◽  
Bruno Augusto Benevenuto de Andrade ◽  
...  

Author(s):  
R. Cruz ◽  
J. Portilla ◽  
P. Gonzáles ◽  
E. Santos ◽  
A. Molotla ◽  
...  

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Qiaochu Sun ◽  
Jae-Seo Lee ◽  
Okjoon Kim ◽  
Young Kim

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