Factors associated with maternal serum C-reactive protein throughout pregnancy: A longitudinal study in women of Rio de Janeiro, Brazil

Nutrition ◽  
2015 ◽  
Vol 31 (9) ◽  
pp. 1103-1108 ◽  
Author(s):  
Livia Costa de Oliveira ◽  
Ana Beatriz Franco-Sena ◽  
Fernanda Rebelo ◽  
Dayana Rodrigues Farias ◽  
Jaqueline Lepsch ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Rio De Janeiro ◽  
Maternal Serum ◽  
C Reactive Protein ◽  
Factors Associated ◽  
Reactive Protein

Abstract P096: Maternal Serum C-Reactive Protein Levels During Pregnancy and Risk for High C-Reactive Protein 7-13 Years Later

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Bonny Rockette-Wagner ◽  
Claudia Holzman ◽  
Bertha L Bullen ◽  
Andrew D Althouse ◽  
Janet M Catov
Keyword(s):  
Relative Risk ◽  
Weight Change ◽  
Elevated Serum ◽  
Maternal Serum ◽  
Health Study ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Inflammatory Status

Introduction: Elevated serum C-reactive protein (CRP) can be a marker of disease activity involving inflammation, such as pregnancy complications and cardiovascular disease (CVD). Systemically high levels of CRP in women, including during pregnancy, may indicate higher risk for CVD. It is unknown if CRP measured during the pro-inflammatory state of pregnancy correlates with concentrations assessed 7-13 years after delivery. Hypothesis: Concentrations of CRP assessed during pregnancy will be related to CRP measured several years after pregnancy, independent of weight gain. Methods: We studied the first 252 women enrolled in the follow-up of the Pregnancy Outcomes and Community Health Study (POUCHmoms 2011-2013) with complete CRP data for the pregnancy (mean gestational age: 22.36 [2.22] weeks) and POUCHmoms visits (mean follow-up: 10.76 [1.38] years). The relative risk for high hsCRP (≥ 3.39 μg/ml) at the follow-up visit, related to quartiles of CRP during pregnancy, was examined using stepwise regression models. Results: Median (IQR) levels of pregnancy CRP and hsCRP at the follow-up visit were 5.68 [3.08, 9.76] and 3.39 [0.69, 9.73] μg/ml, respectively. Although absolute values of hsCRP at follow-up were generally lower than pregnancy CRP, 56% of women in the top and bottom quartiles of pregnancy CRP (71 of 126) were in the same quartile for hsCRP at follow-up (figure). The relative risk of having high hsCRP (≥ 3.39 μg/ml) at follow-up ranged from 2.7-5.2 for the 2 nd - 4 th quartiles of pregnancy CRP (vs. the 1st quartile). Controlling for pre-pregnancy BMI and follow-up weight change, the relative risk of having high hsCRP at follow-up was significantly higher for the 2 nd (1.15 [1.02-1.30]),3 rd (1.19 [1.05-1.35), and 4 th (1.22 [1.05-1.41]) quartiles of pregnancy CRP. Conclusions: Pregnancy CRP levels are related to hsCRP levels several years later in this cohort of women, even after adjusting for pre-pregnancy BMI and follow-up weight change. CRP assessed in pregnancy may reflect inflammatory status later in life.

scholarly journals C-reactive protein/albumin ratio is associated with lung function among children/adolescents with cystic fibrosis: a three-year longitudinal study

2018 ◽  
Vol 136 (1) ◽  
pp. 29-36
Author(s):  
Julia Carvalho Ventura ◽  
Daniela Barbieri Hauschild ◽  
Emília Addison Machado Moreira ◽  
Letícia Cristina Radin Pereira ◽  
Anauã Franco Rosa ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Longitudinal Study ◽  
Lung Function ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein

scholarly journals Maternal Serum C-Reactive Protein for Prediction of Maternal and Perinatal Morbidity in Premature Rupture of Membranes

2021 ◽  
Vol 83 (1) ◽  
pp. 1554-1552
Author(s):  
Ahmed Tawfiek Shaaban ◽  
Amira Ahmed Fathey ◽  
Alaa Masoud Abdelgied ◽  
Ragab Mohamed Dawood ◽  
Marwa Mohammed Dawoud
Keyword(s):  
Maternal Serum ◽  
Perinatal Morbidity ◽  
C Reactive Protein ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Reactive Protein

scholarly journals Changes in pre-diagnostic serum C-reactive protein concentrations and ovarian cancer risk: a longitudinal study

2011 ◽  
Vol 22 (8) ◽  
pp. 1916-1921 ◽  
Author(s):  
A.T. Toriola ◽  
K. Grankvist ◽  
C.B. Agborsangaya ◽  
A. Lukanova ◽  
M. Lehtinen ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Longitudinal Study ◽  
Cancer Risk ◽  
Ovarian Cancer Risk ◽  
C Reactive Protein ◽  
Reactive Protein
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