Orange pulp improves antioxidant status and suppresses lipid peroxidation in orchidectomized male rats

Nutrition ◽  
2007 ◽  
Vol 23 (7-8) ◽  
pp. 617-621 ◽  
Author(s):  
Farzad Deyhim ◽  
Arnulfo Villarreal ◽  
Kristi Garcia ◽  
Ryan Rios ◽  
Claudia Garcia ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Status ◽  
Male Rats ◽  
Orange Pulp

Blood antioxidant status and erythrocyte lipid peroxidation following distance running

1990 ◽  
Vol 282 (1) ◽  
pp. 78-83 ◽  
Author(s):  
Garry G. Duthie ◽  
John D. Robertson ◽  
Ronald J. Maughan ◽  
Philip C. Morrice
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Status ◽  
Distance Running ◽  
Erythrocyte Lipid

The Impact of Concomitant Chronic Pancreatitis on Prooxidant-antioxidant Status and Other Conditions in Osteoarthritis

2016 ◽  
pp. 75-78
Author(s):  
Liliia Babynets ◽  
Tetiana Maevska
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Superoxide Dismutase ◽  
Chronic Pancreatitis ◽  
Functional Capacity ◽  
Antioxidant Status ◽  
Activation Parameters ◽  
Tissue Destruction ◽  
The Impact ◽  
Stress Accumulation

The study proved that patients with combined progress of osteoarthritis and chronic pancreatitis have reliable top-level activation of lipid peroxidation in terms of malonyc aldehyde and tissue destruction in terms of oxyproline, weakening of the antioxidant level (in terms of superoxide dismutase and SH-groups) and activation parameters of catalase and ceruloplasmin (p<0,05). The authentic predictority of patients biological age, duration of combined clinical courses, the functional capacity of the pancreas in terms of fecal α-elastase, structural state by ultrasound criteria for progression effects of oxidative stress, accumulation oxyproline activation parameters catalase and ceruloplasmin, which statistically was reflected by the presence of mainly moderate of significant correlations between these groups of indicators have been identified.

scholarly journals Lipid peroxidation parameters and antioxidant status of critically ill intensive care unit patients

Critical Care ◽  
10.1186/cc142 ◽  
1998 ◽  
Vol 2 (Suppl 1) ◽  
pp. P012 ◽  
Author(s):  
KH Smolle ◽  
G Khoschsorur ◽  
W Wonisch ◽  
F Tatzber
Keyword(s):  
Intensive Care Unit ◽  
Lipid Peroxidation ◽  
Intensive Care ◽  
Critically Ill ◽  
Antioxidant Status

Increased severity of alcoholic liver injury in female rats: role of oxidative stress, endotoxin, and chemokines

2001 ◽  
Vol 281 (6) ◽  
pp. G1348-G1356 ◽  
Author(s):  
Amin A. Nanji ◽  
Kalle Jokelainen ◽  
Maryam Fotouhinia ◽  
Amir Rahemtulla ◽  
Peter Thomas ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Liver Injury ◽  
Fish Oil ◽  
Nonheme Iron ◽  
Female Rats ◽  
Male Rats ◽  
Mrna Levels ◽  
Alcoholic Liver Injury ◽  
Tnf Α ◽  
Cox 2

Alcoholic liver injury is more severe and rapidly developing in women than men. To evaluate the reason(s) for these gender-related differences, we determined whether pathogenic mechanisms important in alcoholic liver injury in male rats were further upregulated in female rats. Male and age-matched female rats (7/group) were fed ethanol and a diet containing fish oil for 4 wk by intragastric infusion. Dextrose isocalorically replaced ethanol in control rats. We analyzed liver histopathology, lipid peroxidation, cytochrome P-450 (CYP)2E1 activity, nonheme iron, endotoxin, nuclear factor-κB (NF-κB) activation, and mRNA levels of cyclooxygenase-1 (COX-1) and COX-2, tumor necrosis factor-α (TNF-α), monocyte chemotactic protein-1 (MCP-1), and macrophage inflammatory protein-2 (MIP-2). Alcohol-induced liver injury was more severe in female vs. male rats. Female rats had higher endotoxin, lipid peroxidation, and nonheme iron levels and increased NF-κB activation and upregulation of the chemokines MCP-1 and MIP-2. CYP2E1 activity and TNF-α and COX-2 levels were similar in male and female rats. Remarkably, female rats fed fish oil and dextrose also showed necrosis and inflammation. Our findings in ethanol-fed rats suggest that increased endotoxemia and lipid peroxidation in females stimulate NF-κB activation and chemokine production, enhancing liver injury. TNF-α and COX-2 upregulation are probably important in causing liver injury but do not explain gender-related differences.

Influence of cadmium ions on the antioxidant status and lipid peroxidation in mouse liver: protective effects of zinc and selenite ions

2012 ◽  
Vol 29 (04) ◽  
pp. 137-142 ◽  
Author(s):  
Rasa Bernotiene ◽  
Laima Ivanoviene ◽  
Ilona Sadauskiene ◽  
Arunas Liekis ◽  
Leonid Ivanov
Keyword(s):  
Lipid Peroxidation ◽  
Mouse Liver ◽  
Antioxidant Status ◽  
Protective Effects ◽  
Cadmium Ions

Multivitamin and mineral supplementation in 1,2-dimethylhydrazine induced experimental colon carcinogenesis and evaluation of free radical status, antioxidant potential, and incidence of ACF

2012 ◽  
Vol 90 (1) ◽  
pp. 45-54 ◽  
Author(s):  
Albert Baskar Arul ◽  
Ignacimuthu Savarimuthu ◽  
Mohammed A. Alsaif ◽  
Khalid S. Al Numair
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Status ◽  
Reduced Glutathione ◽  
Colon Carcinogenesis ◽  
Aberrant Crypt Foci ◽  
Lipid Hydroperoxides ◽  
Entire Study ◽  
Lipid Peroxidation Products ◽  
Histopathological Alterations ◽  
Mineral Supplementation

This study was performed to determine the chemopreventive and antioxidant status of multivitamin and mineral (0.01% in drinking water, ad libitum) supplements in 1,2-dimethylhydrazine (DMH)-induced experimental colon carcinogenesis. Experimental colon carcinogenesis was induced in male albino Wistar rats by injecting DMH (20 mg·(kg body mass)–1) once weekly for 15 consecutive weeks, and administering a multivitamin supplement in 3 regimes (initiation, post-initiation, and entire experimental period) for 32 weeks. We studied lipid peroxidation products (thiobarbituric acid reactive substances, lipid hydroperoxides, conjugated dienes) in the circulation and in the tissues, antioxidant status (superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and non-enzymatic antioxidant-reduced glutathione) of the tissues, aberrant crypt foci (ACF), and histopathological alterations. DMH-induced rats had an increase in lipid peroxidation products and a lower antioxidant status compared with control animals. Multivitamin and mineral supplementation during the initiation, post-initiation, and the entire study period significantly decreased the levels of lipid peroxidation products in circulation and colonic tissues, significantly elevated the activities of the antioxidant enzymes and reduced glutathione to near normalcy in DMH-induced rats. The incidence of ACF was reduced to 84.1% in rats supplemented with multivitamin and minerals for the entire study and prevented the colonic tissue from histopathological alterations induced by DMH.

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