scholarly journals Synaptic Integration Gradients in Single Cortical Pyramidal Cell Dendrites

Neuron ◽  
2011 ◽  
Vol 69 (5) ◽  
pp. 885-892 ◽  
Author(s):  
Tiago Branco ◽  
Michael Häusser
Keyword(s):  
Pyramidal Cell ◽  
Synaptic Integration ◽  
Cortical Pyramidal Cell

The Cortical Pyramidal Cell as a Set of Interacting Error Backpropagating Dendrites: Mechanism for Discovering Nature’s Order

2003 ◽  
pp. 25-64 ◽  
Author(s):  
Oleg V. Favorov ◽  
Joseph T. Hester ◽  
Douglas G. Kelly ◽  
Dan Ryder ◽  
Mark Tommerdahl
Keyword(s):  
Pyramidal Cell ◽  
Cortical Pyramidal Cell

Spatiotemporal structure of depolarization spread in cortical pyramidal cell populations evoked by diffuse retinal light flashes

1999 ◽  
Vol 16 (1) ◽  
pp. 65-79 ◽  
Author(s):  
DAVID M. SENSEMAN
Keyword(s):  
Visual Cortex ◽  
Pyramidal Cell ◽  
Spatiotemporal Structure ◽  
Retinal Stimulation ◽  
Medial Cortex ◽  
Photodiode Array ◽  
Initial Activation ◽  
Cortical Pyramidal Cell ◽  
Light Flashes ◽  
Stimulation Of

The spatiotemporal structure of cortical activity evoked by diffuse light flashes was investigated in an isolated eyecup-brain preparation of the pond turtle, Pseudemys scripta. By combining a photomicroscopic image of the preparation with voltage-sensitive dye signals recorded by a 464-element photodiode array, the spread of depolarization within different cortical areas could be directly visualized with millisecond temporal resolution. Diffuse stimulation of the contralateral eyecup initially depolarized the visual cortex at the junction between its lateral and medial divisions in a small area rostral of the ventricular eminence. From this point, the depolarization spread at different velocities (10–100 μm/ms) depending upon the direction of travel. Since the initial depolarization was always in the rostral pole, the largest spread invariably occurred in a rostral → caudal direction. Within the confines of the medial visual cortex, depolarization spread at a constant velocity but slowed after entering the adjoining medial cortex. Increasing the stimulus illuminance increased the velocity of spread. Rostrocaudal spread of depolarization was also observed in response to electrical stimulation of the geniculocortical pathway and by direct focal stimulation of the cortical sheet. These data suggest that excitatory connections between pyramidal cell clusters play a prominent role in the initial activation of the cortex by diffuse retinal stimulation.

scholarly journals Perceptron learning and classification in a modeled cortical pyramidal cell

2018 ◽  
Author(s):  
Toviah Moldwin ◽  
Idan Segev
Keyword(s):  
Pyramidal Cell ◽  
Pyramidal Neurons ◽  
Learning Algorithm ◽  
Biophysical Model ◽  
Backpropagation Algorithm ◽  
Dendritic Trees ◽  
Cortical Pyramidal Neurons ◽  
Perceptron Learning ◽  
Perceptron Learning Algorithm ◽  
Cortical Pyramidal Cell

AbstractThe perceptron learning algorithm and its multiple-layer extension, the backpropagation algorithm, are the foundations of the present-day machine learning revolution. However, these algorithms utilize a highly simplified mathematical abstraction of a neuron; it is not clear to what extent real biophysical neurons with morphologically-extended nonlinear dendritic trees and conductance-based synapses could realize perceptron-like learning. Here we implemented the perceptron learning algorithm in a realistic biophysical model of a layer 5 cortical pyramidal cell. We tested this biophysical perceptron (BP) on a memorization task, where it needs to correctly binarily classify 100, 1000, or 2000 patterns, and a generalization task, where it should discriminate between two “noisy” patterns. We show that the BP performs these tasks with an accuracy comparable to that of the original perceptron, though the memorization capacity of the apical tuft is somewhat limited. We concluded that cortical pyramidal neurons can act as powerful classification devices.

The Effect of Inherited Hydrocephalus and Shunt Treatment on Cortical Pyramidal Cell Dendrites in the Infant H-Tx Rat

1996 ◽  
Vol 141 (2) ◽  
pp. 269-279 ◽  
Author(s):  
N.G. Harris ◽  
J.P. McAllister II ◽  
J.M. Conaughty ◽  
H.C. Jones
Keyword(s):  
Pyramidal Cell ◽  
Shunt Treatment ◽  
Cortical Pyramidal Cell

Development of Cortical Pyramidal Cell and Interneuronal Dendrites: a Role for Kainate Receptor Subunits and NETO1

2018 ◽  
Vol 56 (7) ◽  
pp. 4960-4979 ◽  
Author(s):  
Alexander Jack ◽  
Mohammad I. K. Hamad ◽  
Steffen Gonda ◽  
Sebastian Gralla ◽  
Steffen Pahl ◽  
...  
Keyword(s):  
Pyramidal Cell ◽  
Kainate Receptor ◽  
Cortical Pyramidal Cell ◽  
Kainate Receptor Subunits

scholarly journals The Effects of Morphine Self-Administration on Cortical Pyramidal Cell Structure in Addiction-Prone Lewis Rats

2006 ◽  
Vol 17 (1) ◽  
pp. 238-249 ◽  
Author(s):  
I Ballesteros-Yanez ◽  
E Ambrosio ◽  
R Benavides-Piccione ◽  
J Perez ◽  
I Torres ◽  
...  
Keyword(s):  
Pyramidal Cell ◽  
Cell Structure ◽  
Self Administration ◽  
Lewis Rats ◽  
Cortical Pyramidal Cell
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