Macropolycytes: Severe stress time for neutrophils

Hypoxia is a severe stress condition often observed in cancer and chronically inflamed cells and tissues. Extracellular vesicles play pivotal roles in these pathological processes and carry biomolecules that can be detected in many biofluids and may be exploited for diagnostic purposes. Several studies report the effects of hypoxia on extracellular vesicles’ release, molecular content, and biological functions in disease. This review summarizes the most recent findings in this field, highlighting the areas that warrant further investigation.

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Trauma-Informed Spiritual Care: Lifelines for a Healing Journey

Theology Today ◽

10.1177/0040573620961145 ◽

2021 ◽

Vol 77 (4) ◽

pp. 359-371

Author(s):

Deborah van Deusen Hunsinger

Keyword(s):

Lived Experience ◽

Traumatic Stress ◽

Spiritual Care ◽

Collective Trauma ◽

Severe Stress ◽

Healing Journey ◽

Trauma Informed ◽

The Church

The article describes how primary, secondary, intergenerational and collective trauma are intertwined in our lived experience, especially in times of severe stress, such as the current coronavirus pandemic. An argument is made for personal and collective mourning, and for developing an attitude of curiosity, openness, acceptance, and love toward oneself and others who suffer traumatic stress. The foundational lifeline of trust in God is nurtured by the faith and practice of the church through the witness of Scripture, worship, prayer, song, and mutual caring.

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Association between chronic low back pain and degree of stress: a nationwide cross-sectional study

Scientific Reports ◽

10.1038/s41598-021-94001-1 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Sungwoo Choi ◽

Sangun Nah ◽

Hae-Dong Jang ◽

Ji Eun Moon ◽

Sangsoo Han

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Multiple Logistic Regression Analysis ◽

Cross Sectional Study ◽

Low Back ◽

Sectional Study ◽

Severe Stress ◽

Cross Sectional ◽

Korean People ◽

Using Data

AbstractLow back pain (LBP) is a very common health problem worldwide, and has a major impact on quality of life. This is a cross-sectional study using data obtained from the Korea National Health and Nutrition Examination Survey (KNHANES) to investigate the health and nutritional status of Korean people, conducted in 2013, 2014, and 2015. The total of 8,473 patients included in the analysis. A 357 (19.34%) subjects in the chronic LBP group and 1,697 (25.61%) subjects in the no chronic LBP group reported no stress (P < 0.001). The numbers of subjects reporting mild, moderate, and severe stress in the two groups were 934 (50.6%) vs. 3,785 (57.11%), 432 (23.4%) vs. 910 (13.73%), and 123 (6.66%) and 235 (3.55%), respectively (all P < 0.001). Multiple logistic regression analysis with full adjustment for other variables indicated higher OR for severe stress (OR 2.82, P < 0.001) than moderate (OR 2.54, P < 0.001) and mild (OR 1.55, P < 0.001) stress. We confirmed that there was a significant association between chronic LBP and degree of stress. Therefore, the degree of stress should be assessed in clinical treatment of chronic LBP patients.

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Decision Making Under Acute Stress Modeled by an Adaptive Temporal–Causal Network Model

Vietnam Journal of Computer Science ◽

10.1142/s2196888820500244 ◽

2020 ◽

Vol 07 (04) ◽

pp. 433-452 ◽

Cited By ~ 1

Author(s):

S. Sahand Mohammadi Ziabari ◽

Jan Treur

Keyword(s):

Decision Making ◽

Network Model ◽

Real World ◽

Acute Stress ◽

Second Phase ◽

Causal Network ◽

Severe Stress ◽

Modeling Methodology ◽

Network Connections ◽

New Learning

The influence of acute severe stress or extreme emotion based on a Network-Oriented modeling methodology has been addressed here. Adaptive temporal causal network model is an approach to address the phenomena with complexity which cannot be or hard to be explained in a real-world experiment. In the first phase, the suppression of the existing network connections as a consequence of the acute stress modeled and in the second phase relaxing the suppression by giving some time and starting a new learning of the decision making in accordance to presence of stress starts again.

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Effect of cholesterol on the state of the adrenal cortex in severe stress

Bulletin of Experimental Biology and Medicine ◽

10.1007/bf00806373 ◽

1978 ◽

Vol 85 (5) ◽

pp. 569-572 ◽

Cited By ~ 1

Author(s):

B. Ya. Ryzhavskii ◽

M. T. Lutsenko

Keyword(s):

Adrenal Cortex ◽

The State ◽

Severe Stress

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Possible involvement of phosphoenolpyruvate carboxylase and NAD-malic enzyme in response to drought stress. A case study: a succulent nature of the C4-NAD-ME type desert plant, Salsola lanata (Chenopodiaceae)

Functional Plant Biology ◽

10.1071/fp16430 ◽

2017 ◽

Vol 44 (12) ◽

pp. 1219

Author(s):

Zhibin Wen ◽

Mingli Zhang

Keyword(s):

Enzyme Activity ◽

Drought Stress ◽

Phosphoenolpyruvate Carboxylase ◽

Malic Enzyme ◽

C4 Plants ◽

Leaf Water Content ◽

Transcriptional Level ◽

Desert Plant ◽

Severe Stress ◽

Real Time Quantitative Pcr

The co-ordination between the primary carboxylating enzyme phosphoenolpyruvate carboxylase (PEPC) and the further decarboxylating enzymes is crucial to the efficiency of the CO2-concentrating mechanism in C4 plants, and investigations on more types of C4 plants are needed to fully understand their adaptation mechanisms. In this study we investigated the effect of drought on carboxylating enzyme PEPC, and the further decarboxylating NAD-malic enzyme (NAD-ME) of Salsola lanata Pall. (Chenopodiaceae) – an annual succulent C4-NAD-ME subtype desert plant. We investigated enzyme activity at the transcriptional level with real-time quantitative PCR and at the translational level by immunochemical methods, and compared S. lanata with other forms of studied C4 plants under drought stress. Results showed that only severe stress limited PEPC enzyme activity (at pH 8.0) of S. lanata significantly. Considering that PEPC enzyme activity (at pH 8.0) was not significantly affected by phosphorylation, the decrease of PEPC enzyme activity (at pH 8.0) of S. lanata under severe stress may be related with decreased PEPC mRNA. The suggestion of increased phosphorylation of the PEPC enzyme in plants under moderate stress was supported by the ratio of PEPC enzyme activity at pH 7.3/8.0, as PEPC enzyme is inhibited by L-malate and the evidence of the 50% inhibiting concentration of L-malate. NAD-ME activity decreased significantly under moderate and severe stress, and coincided with a change of leaf water content rather than the amount of α-NAD-ME mRNA and protein. Leaf dehydration may cause the decrease of NAD-ME activity under water stress. Compared with other C4 plants, the activities of PEPC and NAD-ME of S. lanata under drought stress showed distinct features.

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Failure Analysis of Coil Racks in a Batch Annealing Furnace Using Finite Element Methods

Volume 12: Mechanics of Solids, Structures, and Fluids ◽

10.1115/imece2020-23409 ◽

2020 ◽

Author(s):

Nicholas J. Walla ◽

Hua You ◽

Xinyu Zhu ◽

Chenn Q. Zhou ◽

Matthew Liddick

Keyword(s):

Finite Element Method ◽

Finite Element ◽

Severe Stress ◽

Annealing Furnace ◽

Simulation Data ◽

Lifting Force ◽

Batch Annealing ◽

Steel Coils ◽

Loading And Unloading ◽

Uneven Heating

Abstract In this work, a series of finite element method simulations were performed on cooling racks used for the loading and unloading of steel coils in a batch annealing furnace. Normal furnace operations were simulated using ANSYS Thermal FEA and ANSYS Mechanical FEA to reproduce the thermal and structural loads experienced by the racks, as well as additional lifting forces representing removal by forklift after annealing. In addition to warping found due to uneven heating from the radiative elements of the furnace, severe stress leading to failure was identified on the base of the racks from the lifting force. These results correspond with failures seen in the actual units. The simulation data was used for design adjustments to reduce the damage from the above sources.

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