Decomposition of six common selenium species found in animal tissues using microwave digestion with nitric acid and ICP-MS

2016 ◽  
Vol 126 ◽  
pp. 92-95 ◽  
Author(s):  
W. Maher ◽  
F. Krikowa ◽  
S. Foster
Keyword(s):  
Nitric Acid ◽  
Microwave Digestion ◽  
Animal Tissues ◽  
Selenium Species ◽  
Icp Ms

Accurate Determination of Total Antimony Using ICP-MS and Optimization Its Extraction Efficiency From Reference and Soil Samples

2018 ◽  
Vol 6 (1) ◽  
pp. 48-58
Author(s):  
Sameer Amereih ◽  
Thomas Meisel ◽  
Wolfhard Wegsheider
Keyword(s):  
Citric Acid ◽  
Reference Materials ◽  
Microwave Digestion ◽  
Accurate Determination ◽  
Ammonium Oxalate ◽  
Ammonium Thiocyanate ◽  
Strong Acid ◽  
Disodium Salt ◽  
Icp Ms ◽  
Ammonium Hydrogen

Two independent digestion techniques (microwave acid digestion with HF and HCl, HNO3 and Na2O2 sintering, respectively) were applied to determine the total Sb concentration in a real soil sample and in reference materials: Icelandic Basalt (BIR-1), Cody Shale (SCo-1) and (Soil-7). ICP-MS was used to determine total antimony concentrations in the digested and the extracted solutions using external calibration and isotope dilution technique. The recoveries of Sb using HF in the acids digestion mixture in closed-vessels microwave digestion system were excellent and the concentrations are in very good agreement with certified or reported concentrations of reference materials. Using closed-vessels combined with microwave heating systems probably prevents the loss of volatile Sb compounds. The use of hydrogen fluoride with other strong acid can help dissociating insoluble antimony silicates. Different extraction reagents were tested for their ability to extract antimony using an ultrasonic bath namely: EDTA disodium salt, potassium hydroxide, citric acid monohydrate, pyridine-2,6-dicarboxylic acid, ammonium acetate, ammonium oxalate, ammonium thiocyanate, ammonium persulphate and di-ammonium hydrogen citrate. A 500 mmol L-1 solution of citric acid pH 1.08 proved to be the most efficient extractant. Optimization of the extraction conditions were investigated by studying the effect of pH, concentration, temperature, time of extraction, the ratio of sample mass to the volume of extractant and the number of consecutive extractions. As a result three consecutive extractions for a total time of 45 min at 80 ˚C was the most efficient condition for Sb extraction. Using these extraction conditions 61%, 3.7% RSD and 42%, 2.2% RSD (n=6) of the total antimony in the real soil and Soil-7 samples, respectively could be extracted.

Determination of elemental impurities of Arsenic, Cadmium, Mercury, Lead and Palladium content in Testosterone propionate by using ICP-MS

2021 ◽  
pp. 195-202
Author(s):  
Suresh P. ◽  
Konda Ravi Kumar
Keyword(s):  
Nitric Acid ◽  
Present Method ◽  
Testosterone Propionate ◽  
Rf Power ◽  
High Toxicity ◽  
Elemental Impurities ◽  
Icp Ms ◽  
Energy Discrimination ◽  
Palladium Content

The aim of the present work is to develop and establish a validated analytical method for the determination of arsenic, cadmium, mercury, lead and palladium content in testosterone propionate by using inductive coupled plasma mass spectroscopy (ICP-MS). Samples were analyzed after a preparation of sample solution by dissolving in suitable solvents of concentrated nitric acid and concentrated hydrochloric acid. In the present method, RF power of 1550 watts, RF matching is 1.80 V, nebulizer flow of 0.10 rps and plasma view at spectrum mode were used. Octopole conditions are He flow is on, He flow rate is 4.3 mL/min and energy discrimination is 3.0 V were used. Significant savings in sample volumes, reagents, analysis cost and time are realized. Arsenic, cadmium, mercury, lead and palladium are primary concerned due to their high toxicity and potential contaminants should be limited in testosterone propionate and the developed method was validated according to ICH and USP guidelines. The correlation coefficient, recovery rate, LOD and LOQ reached the acceptable limits. The validated method was selective, sensitive, rapid and capable of the determination of elemental impurities of arsenic, cadmium, mercury, lead and palladium content in bulk drugs.

Micro-quantity tissue digestion for metal measurements by use of a microwave acid-digestion bomb.

1989 ◽  
Vol 35 (3) ◽  
pp. 488-490 ◽  
Author(s):  
J R Nicholson ◽  
M G Savory ◽  
J Savory ◽  
M R Wills
Keyword(s):  
Nitric Acid ◽  
Reference Material ◽  
Microwave Digestion ◽  
Absorption Spectrometry ◽  
Bovine Liver ◽  
Dry Weight ◽  
Acid Digestion ◽  
Tissue Samples ◽  
Dry Ashing ◽  
Tissue Digestion

Abstract We describe a simple and convenient method for processing small amounts of tissue samples for trace-metal measurements by atomic absorption spectrometry, by use of a modified Parr microwave digestion bomb. Digestion proceeds rapidly (less than or equal to 90 s) in a sealed Teflon-lined vessel that eliminates contamination or loss from volatilization. Small quantities of tissue (5-100 mg dry weight) are digested in high-purity nitric acid, yielding concentrations of analyte that can be measured directly without further sample manipulation. We analyzed National Institute of Standards and Technology bovine liver Standard Reference Material to verify the accuracy of the technique. We assessed the applicability of the technique to analysis for aluminum in bone by comparison with a dry ashing procedure.

scholarly journals Elemental analysis of coffee: a comparison of ICP-MS and AAS methods 

2014 ◽  
Vol 32 (No. 4) ◽  
pp. 354-359 ◽  
Author(s):  
M. Jarošová ◽  
D. Milde ◽  
M. Kuba
Keyword(s):  
Inductively Coupled Plasma ◽  
Microwave Digestion ◽  
Absorption Spectrometry ◽  
Mineral Nutrients ◽  
Multivariate Statistical Methods ◽  
Multivariate Statistical ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Microwave Digestion System

We determined the mineral nutrients and toxic elements (Ca, Cu, Fe, Mg, Zn, Cd, Cr, Mn, Ni, and Pb) in five types of coffee by atomic absorption spectrometry and inductively coupled plasma mass spectrometry. The decomposition of the samples took place in a microwave digestion system with HNO<sub>3</sub> and H<sub>2</sub>O<sub>2</sub> reagents. Partial validation of the method was performed by using the certified reference material (NCS ZC 73014). Univariate and multivariate statistical methods were used to compare both the coffee samples and the techniques used. No significant differences were found between two used methods. Significant differences occurred between the coffee samples but only the application of multivariate statistics helps to distinguish among samples from different locations.

Characterization of Selenium Species in Brazil Nuts by HPLC−ICP-MS and ES-MS

2002 ◽  
Vol 50 (20) ◽  
pp. 5722-5728 ◽  
Author(s):  
Anne P. Vonderheide ◽  
Kazimierz Wrobel ◽  
Sasi S. Kannamkumarath ◽  
Clayton B'Hymer ◽  
Maria Montes-Bayón ◽  
...  
Keyword(s):  
Selenium Species ◽  
Brazil Nuts ◽  
Icp Ms
Sign in / Sign up

Export Citation Format

Share Document