Impact of intrauterine growth restriction and glucocorticoids on brain development: Insights using advanced magnetic resonance imaging

2006 ◽  
Vol 254-255 ◽  
pp. 163-171 ◽  
Author(s):  
Stéphane V. Sizonenko ◽  
Cristina Borradori-Tolsa ◽  
Delphine M. Vauthay ◽  
Gregory Lodygensky ◽  
François Lazeyras ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brain Development ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth

Foetal volumetry using Magnetic Resonance Imaging in intrauterine growth restriction

2012 ◽  
Vol 88 ◽  
pp. S35-S40 ◽  
Author(s):  
Mellisa S. Damodaram ◽  
Lisa Story ◽  
Elisanda Eixarch ◽  
Prachi Patkee ◽  
Abhilasha Patel ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth

scholarly journals Magnetic Resonance Imaging in Pregnancy with Intrauterine Growth Restriction: A Pilot Study

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Serafina Perrone ◽  
Antonino Santacroce ◽  
Giuseppe de Bernardo ◽  
Maria Gabriella Alagna ◽  
Salvatore Francesco Carbone ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Amniotic Fluid ◽  
Fetal Growth ◽  
Gestational Age ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth ◽  
Respiratory Outcome

Objective. Intrauterine growth restriction (IUGR) is a major cause of late stillbirth, though not all compromised babies remain small or are considered growth restricted as pregnancy progresses. Fetal Magnetic Resonance Imaging (f-MRI) represents a second-line tool to study pregnancies with IUGR fetuses. The aim of our study was to evaluate the usefulness of f-MRI on predicting fetal growth and the offspring’s perinatal respiratory outcome. Design. All f-MRI performed between 2014 and 2016 in Siena were analysed. Pregnancies with IUGR (Study group (SG)) were recruited together with a control population (Control group (CG)), coupled for gestational age (GA) at the time of f-MRI (mean GA 31 wks). Neonatal information was collected. The f-MRI protocol consisted of T2w images. Six regions of interest (ROI) were placed as follows: 2 on the lung, 2 on the liver, and 2 on the amniotic fluid. The signal intensities (SI) of each ROI were measured. The SI lung to liver ratio (SI lung/liver) and SI lung to amniotic fluid ratio (SI lung/amniotic fluid) were obtained for each fetus. Each ratio was compared between SG and CG. Therefore, SG was divided into two subgroups: adequate and small for gestational age (AGA and SGA) newborns. All measurements were related to offspring’s perinatal respiratory outcome. Results. SI lung/liver was linearly related with GA at the time of f-MRI and with EFW. SI lung/amniotic fluid was significantly higher in SG than in CG (p=0,014). In contrast, among SG, lower values of SI lung/amniotic fluid were found in the SGA compared to AGA (p=0,036). The days of oxygen supply were higher in the SGA subgroup than in the AGA subgroup (p=0,028). Conclusions. SI lung/liver increases with fetal lung maturation and appears to be useful to estimate intrauterine fetal growth. SI lung/amniotic fluid seems to be a reliable predictive index to distinguish the IUGR fetuses that can recover their growth from those that were born SGA. f-MRI represents a promising frontier to predict IUGR fetus outcome, thus contributing to ameliorate the perinatal management.

scholarly journals Magnetic resonance imaging of skull and brain parameters in fetuses with intrauterine growth restriction

2021 ◽  
Vol 54 (3) ◽  
pp. 141-147
Author(s):  
Ronaldo Eustáquio de Oliveira Júnior ◽  
Sara Reis Teixeira ◽  
Eduardo Félix Martins Santana ◽  
Jorge Elias Junior ◽  
Fabricio da Silva Costa ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Intrauterine Growth Restriction ◽  
Normal Growth ◽  
Growth Restriction ◽  
Resonance Imaging ◽  
Intrauterine Growth ◽  
Magnetic Resonance Imaging Mri ◽  
Length And Area ◽  
Brain Measurements

Abstract Objective: To compare fetuses with intrauterine growth restriction (IUGR) and those with normal growth, in terms of skull and brain measurements obtained by magnetic resonance imaging (MRI). Materials and Methods: This was a prospective cohort study including 26 single fetuses (13 with IUGR and 13 with normal growth), evaluated from 26 to 38 weeks of gestation. Using MRI, we measured skull and brain biparietal diameters (BPDs); skull and brain occipitofrontal diameters (OFDs); corpus callosum length and area; transverse cerebellar diameter; extracerebral cerebrospinal fluid (eCSF); and right and left interopercular distances (IODs). Results: The following were significantly smaller in IUGR fetuses than in control fetuses: skull BPD (76.9 vs. 78.2 mm; p = 0.0029); brain BPD (67.8 vs. 71.6 mm; p = 0.0064); skull OFD (93.6 vs. 95 mm; p = 0.0010); eCSF (5.5 vs. 8.2 mm; p = 0.0003); right IOD (9.8 vs. 13.9 mm; p = 0.0023); and left IOD (11.8 vs. 16.3 mm; p = 0.0183). The skull BPD/eCSF, brain BPD/eCSF, skull OFD/eCSF, and brain OFD/eCSF ratios were also lower in IUGR fetuses. Conclusion: IUGR fetuses had smaller OFD and BPD, both skull and brain, and less eCSF when compared to normal growth fetuses.

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