Vitamin D and walking speed in older adults: Systematic review and meta-analysis

Maturitas ◽  
2017 ◽  
Vol 106 ◽  
pp. 8-25 ◽  
Author(s):  
Cedric Annweiler ◽  
Samir Henni ◽  
Stéphane Walrand ◽  
Manuel Montero-Odasso ◽  
Gustavo Duque ◽  
...  
Maturitas ◽  
2017 ◽  
Vol 100 ◽  
pp. 8-15 ◽  
Author(s):  
Paola Lucato ◽  
Marco Solmi ◽  
Stefania Maggi ◽  
Anna Bertocco ◽  
Giulia Bano ◽  
...  

2018 ◽  
Vol 49 ◽  
pp. 1-22 ◽  
Author(s):  
Priya Dewansingh ◽  
Alida Melse-Boonstra ◽  
Wim P. Krijnen ◽  
Cees P. van der Schans ◽  
Harriët Jager-Wittenaar ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2286 ◽  
Author(s):  
Diego Marcos-Pérez ◽  
María Sánchez-Flores ◽  
Stefania Proietti ◽  
Stefano Bonassi ◽  
Solange Costa ◽  
...  

Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low levels of vitamin D and mortality. Hence, we conducted a systematic review of the literature and meta-analysis to test the possible association of low concentrations of serum 25-hydroxyvitamin D (25(OH)D), a marker of vitamin D status, with frailty in later life. We reviewed cross-sectional or longitudinal studies evaluating populations of older adults and identifying frailty by a currently validated scale. Meta-analyses were restricted to cross-sectional data from studies using Fried’s phenotype to identify frailty. Twenty-six studies were considered in the qualitative synthesis, and thirteen studies were included in the meta-analyses. Quantitative analyses showed significant differences in the comparisons of frail (standardized mean difference (SMD)—1.31, 95% confidence interval (CI) (−2.47, −0.15), p = 0.0271) and pre-frail (SMD—0.79, 95% CI (−1.58, −0.003), p = 0.0491) subjects vs. non-frail subjects. Sensitivity analyses reduced heterogeneity, resulting in a smaller but still highly significant between-groups difference. Results obtained indicate that lower 25(OH)D levels are significantly associated with increasing frailty severity. Future challenges include interventional studies testing the possible benefits of vitamin D supplementation in older adults to prevent/palliate frailty and its associated outcomes.


2010 ◽  
Vol 58 (7) ◽  
pp. 1299-1310 ◽  
Author(s):  
Rita Rastogi Kalyani ◽  
Brady Stein ◽  
Ritu Valiyil ◽  
Rebecca Manno ◽  
Janet W. Maynard ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document