T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures

Bone ◽  
2006 ◽  
Vol 39 (5) ◽  
pp. 1097-1106 ◽  
Author(s):  
Annie W.C. Kung ◽  
Billy M.H. Lai ◽  
Mandy Y.M. Ng ◽  
Vivian Chan ◽  
Pak C. Sham
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Bone Mineral ◽  
Estrogen Receptor Beta ◽  
Osteoporotic Fractures ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Receptor Beta

scholarly journals Association Between moleculars and Osteoporotic Fracture Risk:A systematical review

2020 ◽  
Author(s):  
Jie-Yu Liu ◽  
Jia-Xiang Wang ◽  
Li Xu ◽  
Shu-Feng Lei ◽  
Fei-Yan Deng
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Elderly Population ◽  
Early Recognition ◽  
Osteoporotic Fractures ◽  
Middle Aged ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Increased Risk

AbstractOsteoporosis is a systemic chronic skeletal disease, which is characterized by low bone mineral density (BMD) and increased risk to osteoporotic fractures (OFs). OFs are associated with high mortality and morbidity, and seriously affect the life quality of patients. Osteoporosis is prevalent in the middle-aged and elderly population, especially the postmenopausal women. With population aging, osteoporosis becomes a world-wide serious public health problem. Early recognition of the high-risk population followed by timely and efficient intervention and/or treatment is important for preventing OFs. In light of the high heritability and complex pathogenesis of OP, comprehensive consideration of significant biological/biochemical factors is necessary for accurate risk evaluation. For this purpose, we reviewed recent research progress on moleculars which are diagnostic and/or predictive of OFs risk. Future integrative analyses and systematic evaluation of these moleculars may facilitate developing novel methodologies and/or test strategies, i.e., biochips, for early recognition of osteoporosis, hence to contribute to preventing OFs in the world.Graphical AbstractOsteoporosis, which is characterized by low bone mineral density (BMD) and increased risk to osteoporotic fractures (OFs), is prevalent in the middle-aged and elderly population, especially in the postmenopausal women. We focused on several types of important molecules, including proteins/peptides, RNAs, lipids, to gain comprehensive understanding and to generate novel perspectives in predicting and diagnosing OFs.

Evaluation with densitometry of patients with breast cancer and low bone mineral density after 2 years of treatment

2013 ◽  
Author(s):  
Sonia Munoz Gil ◽  
Tomas Mut Dolera ◽  
Belen C Garrido Lopez ◽  
M D Torregrosa Maicas ◽  
R Girones Sarrio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Low Bone Mineral Density
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