Unzipped multiwalled carbon nanotubes-incorporated poly(l-lactide) nanocomposites with enhanced interface and hydrolytic degradation

2012 ◽  
Vol 134 (2-3) ◽  
pp. 1059-1066 ◽  
Author(s):  
Linghao He ◽  
Jing Sun ◽  
Xiuxin Wang ◽  
Xuehui Fan ◽  
Qiaoling Zhao ◽  
...  
Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2588
Author(s):  
Nader Tanideh ◽  
Negar Azarpira ◽  
Najmeh Sarafraz ◽  
Shahrokh Zare ◽  
Aida Rowshanghiyas ◽  
...  

Appropriate selection of suitable materials and methods is essential for scaffolds fabrication in tissue engineering. The major challenge is to mimic the structure and functions of the extracellular matrix (ECM) of the native tissues. In this study, an optimized 3D structure containing poly(3-hydroxybutyrate) (P3HB), multiwalled carbon nanotubes (MCNTs) and curcumin (CUR) was created by electrospinning a novel biomimetic scaffold. CUR, a natural anti-inflammatory compound, has been selected as a bioactive component to increase the biocompatibility and reduce the potential inflammatory reaction of electrospun scaffolds. The presence of CUR in electrospun scaffolds was confirmed by 1H NMR and Fourier-transform infrared spectroscopy (FTIR). Scanning electron microscopy (SEM) revealed highly interconnected porosity of the obtained 3D structures. Addition of up to 20 wt% CUR has enhanced mechanical properties of the scaffolds. CUR has also promoted in vitro bioactivity and hydrolytic degradation of the electrospun nanofibers. The developed P3HB-MCNT composite scaffolds containing 20 wt% of CUR revealed excellent in vitro cytocompatibility using mesenchymal stem cells and in vivo biocompatibility in rat animal model study. Importantly, the reduced inflammatory reaction in the rat model after 8 weeks of implantation has also been observed for scaffolds modified with CUR. Overall, newly developed P3HB-MCNTs-CUR electrospun scaffolds have demonstrated their high potential for tissue engineering applications.


2019 ◽  
Vol 137 (10) ◽  
pp. 48439 ◽  
Author(s):  
Esperanza Díaz ◽  
Igor Puerto ◽  
Iban Sandonis ◽  
Sylvie Ribeiro ◽  
Senentxu Lanceros‐Mendez

2012 ◽  
Vol 2 (6) ◽  
pp. 166-168 ◽  
Author(s):  
Dr.T.Ch.Madhavi Dr.T.Ch.Madhavi ◽  
◽  
Pavithra.P Pavithra.P ◽  
Sushmita Baban Singh Sushmita Baban Singh ◽  
S.B.Vamsi Raj S.B.Vamsi Raj ◽  
...  

2018 ◽  
Vol 69 (5) ◽  
pp. 1233-1239
Author(s):  
Raluca Madalina Senin ◽  
Ion Ion ◽  
Ovidiu Oprea ◽  
Rusandica Stoica ◽  
Rodica Ganea ◽  
...  

In this study, non-irradiated and weathered multiwalled carbon nanotubes (MWCNTs) obtained through irradiation, were studied as adsorbents for BPA, both nanomaterials being characterized before and after the adsorption process. The objectives of our investigation were to compare the characteristics of non-irradiated and irradiated MWCNTs, to evaluate the adsorption capacity of BPA by pristine and irradiated MWCNTs and to determine the variation of the kinetic, sorption and thermodynamic parameters during sorption process using both sorbents.


2020 ◽  
Vol 16 (7) ◽  
pp. 905-913
Author(s):  
Youyuan Peng ◽  
Qingshan Miao

Background: L-Ascorbic acid (AA) is a kind of water soluble vitamin, which is mainly present in fruits, vegetables and biological fluids. As a low cost antioxidant and effective scavenger of free radicals, AA may help to prevent diseases such as cancer and Parkinson’s disease. Owing to its role in the biological metabolism, AA has also been utilized for the therapy of mental illness, common cold and for improving the immunity. Therefore, it is very necessary and urgent to develop a simple, rapid and selective strategy for the detection of AA in various samples. Methods: The molecularly imprinted poly(o-phenylenediamine) (PoPD) film was prepared for the analysis of L-ascorbic acid (AA) on gold nanoparticles (AuNPs) - multiwalled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE) by electropolymerization of o-phenylenediamine (oPD) and AA. Experimental parameters including pH value of running buffer and scan rates were optimized. Scanning electron microscope (SEM), fourier-transform infrared (FTIR) spectra, cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were utilized for the characterization of the imprinted polymer film. Results: Under the selected experimental conditions, the DPV peak currents of AA exhibit two distinct linear responses ranging from 0.01 to 2 μmol L-1 and 2 to 100 μmol L-1 towards the concentrations of AA, and the detection limit was 2 nmol L-1 (S/N=3). Conclusion: The proposed electrochemical sensor possesses excellent selectivity for AA, along with good reproducibility and stability. The results obtained from the analysis of AA in real samples demonstrated the applicability of the proposed sensor to practical analysis.


Sign in / Sign up

Export Citation Format

Share Document