Hydrolytic degradation and cytotoxicity of poly(lactic‐ co ‐glycolic acid)/multiwalled carbon nanotubes for bone regeneration

2019 ◽  
Vol 137 (10) ◽  
pp. 48439 ◽  
Author(s):  
Esperanza Díaz ◽  
Igor Puerto ◽  
Iban Sandonis ◽  
Sylvie Ribeiro ◽  
Senentxu Lanceros‐Mendez
Keyword(s):  
Carbon Nanotubes ◽  
Bone Regeneration ◽  
Multiwalled Carbon Nanotubes ◽  
Glycolic Acid ◽  
Hydrolytic Degradation ◽  
Multiwalled Carbon

scholarly journals Poly(3-Hydroxybutyrate)-Multiwalled Carbon Nanotubes Electrospun Scaffolds Modified with Curcumin

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2588
Author(s):  
Nader Tanideh ◽  
Negar Azarpira ◽  
Najmeh Sarafraz ◽  
Shahrokh Zare ◽  
Aida Rowshanghiyas ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Engineering ◽  
Multiwalled Carbon Nanotubes ◽  
Inflammatory Reaction ◽  
3D Structure ◽  
Hydrolytic Degradation ◽  
Multiwalled Carbon ◽  
Electrospun Scaffolds

Appropriate selection of suitable materials and methods is essential for scaffolds fabrication in tissue engineering. The major challenge is to mimic the structure and functions of the extracellular matrix (ECM) of the native tissues. In this study, an optimized 3D structure containing poly(3-hydroxybutyrate) (P3HB), multiwalled carbon nanotubes (MCNTs) and curcumin (CUR) was created by electrospinning a novel biomimetic scaffold. CUR, a natural anti-inflammatory compound, has been selected as a bioactive component to increase the biocompatibility and reduce the potential inflammatory reaction of electrospun scaffolds. The presence of CUR in electrospun scaffolds was confirmed by 1H NMR and Fourier-transform infrared spectroscopy (FTIR). Scanning electron microscopy (SEM) revealed highly interconnected porosity of the obtained 3D structures. Addition of up to 20 wt% CUR has enhanced mechanical properties of the scaffolds. CUR has also promoted in vitro bioactivity and hydrolytic degradation of the electrospun nanofibers. The developed P3HB-MCNT composite scaffolds containing 20 wt% of CUR revealed excellent in vitro cytocompatibility using mesenchymal stem cells and in vivo biocompatibility in rat animal model study. Importantly, the reduced inflammatory reaction in the rat model after 8 weeks of implantation has also been observed for scaffolds modified with CUR. Overall, newly developed P3HB-MCNTs-CUR electrospun scaffolds have demonstrated their high potential for tissue engineering applications.

Wrapping Multiwalled Carbon Nanotubes with Anatase Titanium Oxide for the Electrosynthesis of Glycolic Acid

2019 ◽  
Vol 2 (10) ◽  
pp. 6360-6367 ◽  
Author(s):  
Jun Yang ◽  
Junfang Cheng ◽  
Jie Tao ◽  
Manabu Higashi ◽  
Miho Yamauchi ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Titanium Oxide ◽  
Multiwalled Carbon Nanotubes ◽  
Glycolic Acid ◽  
Multiwalled Carbon

Effect of Multiwalled Carbon Nanotubes On Mechanical Properties of Concrete

2012 ◽  
Vol 2 (6) ◽  
pp. 166-168 ◽  
Author(s):  
Dr.T.Ch.Madhavi Dr.T.Ch.Madhavi ◽  
◽  
Pavithra.P Pavithra.P ◽  
Sushmita Baban Singh Sushmita Baban Singh ◽  
S.B.Vamsi Raj S.B.Vamsi Raj ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Carbon Nanotubes ◽  
Multiwalled Carbon Nanotubes ◽  
Multiwalled Carbon
Sign in / Sign up

Export Citation Format

Share Document