scholarly journals The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation

2007 ◽  
Vol 26 (1) ◽  
pp. 42-53 ◽  
Author(s):  
Noriaki Mori ◽  
Tokifumi Majima ◽  
Norimasa Iwasaki ◽  
Shigeyuki Kon ◽  
Kiyoshi Miyakawa ◽  
...  
2019 ◽  
Vol 64 (1-2) ◽  
pp. 75-82
Author(s):  
F. Nekvapil ◽  
◽  
Cs. Müller Molnár ◽  
S. Tomšić ◽  
S. Cintă Pinzaru ◽  
...  

1985 ◽  
Vol 49 ◽  
Author(s):  
Martin Stutzmann ◽  
Warren B. Jackson ◽  
Chuang Chuang Tsai

AbstractThe dependence of the creation and the annealing of metastable dangling bonds in hydrogenated amorphous silicon on various material parameters will be discussed in the context of a recently proposed model. After a brief review of the kinetic behaviour governing defect creation and annealing in undoped a- Si:H, a number of special cases will be analyzed: the influence of alloying with O, N, C, and Ge, changes introduced by doping and compensation, and the role of mechanical stress. Finally, possibilities to increase the stability of a-Si:H based devices will be examined.


2016 ◽  
Vol 18 (6) ◽  
pp. 4721-4727 ◽  
Author(s):  
Bo Lu ◽  
Yicheng Song ◽  
Qinglin Zhang ◽  
Jie Pan ◽  
Yang-Tse Cheng ◽  
...  

The crucial role of mechanical stress in voltage hysteresis of lithium ion batteries in charge–discharge cycles is investigated theoretically and experimentally.


Endocrinology ◽  
2013 ◽  
Vol 154 (10) ◽  
pp. 3525-3538 ◽  
Author(s):  
Hong Guo ◽  
Merlijn Bazuine ◽  
Daozhong Jin ◽  
Merry M. Huang ◽  
Samuel W. Cushman ◽  
...  

Lipocalin 2 (Lcn2) has previously been characterized as an adipokine/cytokine playing a role in glucose and lipid homeostasis. In this study, we investigate the role of Lcn2 in adipose tissue remodeling during high-fat diet (HFD)-induced obesity. We find that Lcn2 protein is highly abundant selectively in inguinal adipose tissue. During 16 weeks of HFD feeding, the inguinal fat depot expanded continuously, whereas the expansion of the epididymal fat depot was reduced in both wild-type (WT) and Lcn2−/− mice. Interestingly, the depot-specific effect of HFD on fat mass was exacerbated and appeared more pronounced and faster in Lcn2−/− mice than in WT mice. In Lcn2−/− mice, adipocyte hypertrophy in both inguinal and epididymal adipose tissue was more profoundly induced by age and HFD when compared with WT mice. The expression of peroxisome proliferator-activated receptor-γ protein was significantly down-regulated, whereas the gene expression of extracellular matrix proteins was up-regulated selectively in epididymal adipocytes of Lcn2−/− mice. Consistent with these observations, collagen deposition was selectively higher in the epididymal, but not in the inguinal adipose depot of Lcn2−/− mice. Administration of the peroxisome proliferator-activated receptor-γ agonist rosiglitazone (Rosi) restored adipogenic gene expression. However, Lcn2 deficiency did not alter the responsiveness of adipose tissue to Rosi effects on the extracellular matrix expression. Rosi treatment led to the further enlargement of adipocytes with improved metabolic activity in Lcn2−/− mice, which may be associated with a more pronounced effect of Rosi treatment in reducing TGF-β in Lcn2−/− adipose tissue. Consistent with these in vivo observations, Lcn2 deficiency reduces the adipocyte differentiation capacity of stromal-vascular cells isolated from HFD-fed mice in these cells. Herein Rosi treatment was again able to stimulate adipocyte differentiation to a similar extent in WT and Lcn2−/− inguinal and epididymal stromal-vascular cells. Thus, combined, our data indicate that Lcn2 has a depot-specific role in HFD-induced adipose tissue remodeling.


2015 ◽  
Vol 5 (1) ◽  
pp. 40 ◽  
Author(s):  
Shiro Mizuno ◽  
Harm Jan Bogaard ◽  
Takeshi Ishizaki ◽  
Hirohisa Toga

2021 ◽  
pp. 1-3
Author(s):  
Barassi Giovanni ◽  
Guerri Sergio ◽  
Tavani Roberta ◽  
Ricucci Giampiero ◽  
De Luca Giorgia ◽  
...  

There is an interrelation with ultrasound / physiotherapist and the duty of the physiotherapist to know how to perform ultrasound examinations alone, not for diagnostic purposes, to follow the evolution of the therapeutic cycle of physiotherapy. For this reason, ultrasound image analysis (US) is a promising non-invasive approach that uses load-dependent changes in the intensity of the echo to characterize the rigidity of muscle and tendon tissue. The purpose of this contribution is to improve the use of ultrasound images (US) and the role of the physiotherapist, who are able to detect localized changes, in particular in stiffness of the tendon due to partial and full-thickness tendon tears. Image intensity information is less sensitive for identifying load transmission variations resulting from partial thickness cuts initiated on the joint side. Ultrasound images can be useful for quantitatively assessing the variations dependent on the tendon load and muscle stiffness in physiotherapy and that the interruption of the behavior of the acousto-elastic ultrasound images can be indicative of substantial damage to the muscle or tendon.


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