scholarly journals Frontal plane knee mechanics and medial cartilage MR relaxation times in individuals with ACL reconstruction: A pilot study

The Knee ◽  
2014 ◽  
Vol 21 (5) ◽  
pp. 881-885 ◽  
Author(s):  
Deepak Kumar ◽  
Abbas Kothari ◽  
Richard B. Souza ◽  
Samuel Wu ◽  
C. Benjamin Ma ◽  
...  
Keyword(s):  
Pilot Study ◽  
Acl Reconstruction ◽  
Relaxation Times ◽  
Frontal Plane ◽  
Knee Mechanics ◽  
Mr Relaxation

scholarly journals Changes in MR relaxation times of the meniscal body with loading: an in vivo pilot study in knee osteoarthritis

2013 ◽  
Vol 21 ◽  
pp. S213
Author(s):  
K. Subburaj ◽  
R.B. Souza ◽  
B.T. Wyman ◽  
X. Li ◽  
T.M. Link ◽  
...  
Keyword(s):  
Pilot Study ◽  
Knee Osteoarthritis ◽  
Relaxation Times ◽  
Mr Relaxation

scholarly journals Changes in MR relaxation times of the meniscus with acute loading: An in vivo pilot study in knee osteoarthritis

2013 ◽  
Vol 41 (2) ◽  
pp. 536-543 ◽  
Author(s):  
Karupppasamy Subburaj ◽  
Richard B. Souza ◽  
Bradley T. Wyman ◽  
Marie-Pierre Hellio Le Graverand-Gastineau ◽  
Xiaojuan Li ◽  
...  
Keyword(s):  
Pilot Study ◽  
Knee Osteoarthritis ◽  
Relaxation Times ◽  
Mr Relaxation

scholarly journals Frontal Plane Knee Mechanics and Early Cartilage Degeneration in People With Anterior Cruciate Ligament Reconstruction: A Longitudinal Study

2017 ◽  
Vol 46 (2) ◽  
pp. 378-387 ◽  
Author(s):  
Deepak Kumar ◽  
Favian Su ◽  
Daniel Wu ◽  
Valentina Pedoia ◽  
Lauren Heitkamp ◽  
...  
Keyword(s):  
Cruciate Ligament ◽  
Relaxation Times ◽  
Frontal Plane ◽  
Cartilage Degeneration ◽  
Medial Knee ◽  
Peak Knee ◽  
Knee Loading ◽  
Mr Relaxation ◽  
Injured Knee ◽  
Over Time

Background: Abnormal frontal plane gait mechanics are known risk factors for knee osteoarthritis, but their role in early cartilage degeneration after anterior cruciate ligament reconstruction (ACLR) is not well understood. Hypothesis/Purpose: The objective was to evaluate the association of frontal plane gait mechanics with medial knee cartilage magnetic resonance (MR) relaxation times over 1 year in patients with ACLR and controls. It was hypothesized that (1) there will be an increase in frontal plane medial knee loading and medial knee MR relaxation times over time in the patients with ACLR, and (2) increases in frontal plane medial knee loading will be associated with an increase in medial knee MR relaxation times. Study Design: Case-control study; Level of evidence, 3. Methods: Patients with ACLR (n = 37) underwent walking gait analyses and bilateral quantitative MR imaging (MRI) before surgery and at 6 and 12 months after ACLR. Healthy control participants (n = 13) were evaluated at baseline and 12 months. Gait variables included peak knee adduction moment (KAM), KAM impulse, and peak knee adduction angle. MRI variables included medial femur and medial tibia whole compartment and subregional T1ρ and T2 relaxation times. Statistical analyses included a comparison of changes over time for gait and MRI variables, correlations between changes in gait and MRI variables over time, and differences in change in MRI variables in patients who showed an increase versus decrease in KAM impulse. Results: There were significant increases in medial T1ρ (Δ 4%-11%) and T2 (Δ 2%-10%) relaxation times from baseline to 6 months for both knees in the ACLR group and in KAM (Δ 13%) for the injured knee. From baseline to 6 months, patients who had an increase in KAM impulse in the injured knee had a greater increase in medial T1ρ and T2 relaxation times as compared with those who did not have an increase in KAM impulse. Longitudinal changes for the control group were not significant. Conclusion: There is an increase in medial knee relaxation times over the first 6 months after ACLR. People with an increase in medial knee loading show an increase in medial knee relaxation times when compared with those who do not have an increase in medial knee loading over the first 6 months.

Knee Cartilage T 2 Relaxation Times 3 Months after ACL Reconstruction Are Associated with Knee Gait Variables Linked to Knee Osteoarthritis

2021 ◽  
Author(s):  
Jack R. Williams ◽  
Kelsey Neal ◽  
Abdulmajeed Alfayyadh ◽  
Kendra Lennon ◽  
Jacob J. Capin ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Acl Reconstruction ◽  
Relaxation Times ◽  
Knee Cartilage

scholarly journals ACL Graft Signal Characteristics Measured by Quantitative MRI Are Significantly Correlated with Patient Reported Outcomes Two-Years after Hamstring Autograft ACL Reconstruction

2019 ◽  
Vol 7 (7_suppl5) ◽  
pp. 2325967119S0035
Author(s):  
Drew A. Lansdown ◽  
Weiyuan Xiao ◽  
Alan L. Zhang ◽  
Christina R. Allen ◽  
Brian T. Feeley ◽  
...  
Keyword(s):  
Acl Reconstruction ◽  
Quantitative Imaging ◽  
Relaxation Times ◽  
Tendon Graft ◽  
Hamstring Autograft ◽  
Acl Graft ◽  
Non Invasive ◽  
Patient Reported ◽  
Proteoglycan Content ◽  
Over Time

Objectives: Following surgical reconstruction of the anterior cruciate ligament (ACL), the tendon graft undergoes a remodeling process of ligamentization. Collagen within the ACL graft becomes organized along the long-axis of the ligament and the proteoglycan content increases. Quantitative imaging sequences, specifically T2 and T1rho, allow for a non-invasive assessment of collagen orientation and proteoglycan content, respectively. The purpose of this study was to investigate the longitudinal progression of T2 and T1rho relaxation times of the graft after ACL reconstruction and the relationship between these quantitative imaging markers and patient-reported outcome measures. We hypothesized that T2 and T1rho would decrease significantly over time, reflecting improved collagen organization and ncreased proteoglycan content, and that T2 and T1rho relaxation times would be inversely correlated with Knee Osteoarthritis Outcome Scores (KOOS). Methods: Thirty-two patients (mean age 29.4±8.2 years, 12 females) were followed prospectively after arthroscopic ACL reconstruction with hamstring autograft. Patients provided informed consent and all procedures were IRB-approved. Exclusion criteria included allograft reconstruction, other ligamentous injury, meniscal tear requiring repair, prior knee surgery, or history of arthritis. Post-operative MR imaging was obtained for 31 patients at 6 months, 30 patients at 12 months, 26 patients at 24 months, and 23 patients at 36 months after surgery. T2 and T1rho relaxation times were simultaneously acquired with a combined 3D sagittal sequence using a 3 T MR system (GE Healthcare) with a 1Tx/8Rx knee coil. The intra-articular ACL graft was identified on a fat-suppressed sagittal high-resolution 3D fast spin echo images and manually segmented. The T2 and T1rho relaxation times for the graft were recorded. Patients completed the KOOS at each imaging time point. Repeated measures analysis of variance (ANOVA) tests with Tukey corrections were used to compare T2 and T1rho relaxation times between time points. The relationship between KOOS and T2 and T1rho values at 2 years post-operative was investigated with Spearman’s rank correlation. Significance was defined as p<0.05. Results: The T2 relaxation times of the ACL graft were significantly higher at 6 months relative to 12 months (p<0.001), 24 months (p<0.001,) and 36 months (p<0.001) after ACL reconstruction, as well as significantly higher at 12 months relative to 36 months (p<0.001) (Figure 1A). The T1rho relaxation times of the ACL graft were significantly higher at 6 months relative to 12 months (p<0.001), 24 months (p<0.001), and 36 months (p<0.001) (Figure 1B). The two-year T2 relaxation times and T1rho relaxation times were significantly correlated with the KOOS Sports, Pain, Symptoms, and Activities of Daily Living sub-scores. Conclusion: We observed significant changes in the tendon graft over time following ACL reconstruction with hamstring autograft, reflecting a higher concentration of proteoglycan and more longitudinally-organized collagen structure over time. Improved collagen organization (lower T2 values) and increased proteoglycan content (lower T1rho values) were correlated with better outcomes based on KOOS scores. Quantitative T2 and T1rho relaxation times of ACL graft may offer a non-invasive method for monitoring graft maturation that correlates with patient-reported knee function after ACL reconstruction. [Figure: see text][Table: see text]

scholarly journals Gait Asymmetry Can Predict Functional Performance Post ACL Reconstruction: A Pilot Study

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 258-259
Author(s):  
Yasir Alshehri ◽  
Marcio Santos ◽  
Scott Mullen ◽  
Bryan Vopat ◽  
Paul Schroeppel ◽  
...  
Keyword(s):  
Pilot Study ◽  
Acl Reconstruction ◽  
Functional Performance ◽  
Gait Asymmetry

Post-ECT increases in MRI regional T2 relaxation times and their relationship to cognitive side effects: A pilot study

1994 ◽  
Vol 54 (2) ◽  
pp. 177-184 ◽  
Author(s):  
David J. Diehl ◽  
Matcheri S. Keshavan ◽  
Emanuel Kanal ◽  
Robert D. Nebes ◽  
Thomas E. Nichols ◽  
...  
Keyword(s):  
Pilot Study ◽  
Side Effects ◽  
Relaxation Times ◽  
T2 Relaxation ◽  
Cognitive Side Effects

scholarly journals Effects of Isolated Hip Abductor Fatigue on Frontal Plane Knee Mechanics

2010 ◽  
Vol 42 (3) ◽  
pp. 535-545 ◽  
Author(s):  
CHRISTOPHER F. GEISER ◽  
KRISTIAN M. O'CONNOR ◽  
JENNIFER E. EARL
Keyword(s):  
Frontal Plane ◽  
Knee Mechanics ◽  
Hip Abductor

3D Hip And Knee Mechanics During Hop Tests After ACL Reconstruction Measured With Inertial Sensors

2017 ◽  
Vol 49 (5S) ◽  
pp. 497-498
Author(s):  
Jasper Reenalda ◽  
Erik Maartens ◽  
Paul Kline ◽  
Jaap Buurke ◽  
Mary Lloyd Ireland ◽  
...  
Keyword(s):  
Acl Reconstruction ◽  
Inertial Sensors ◽  
Hop Tests ◽  
Knee Mechanics
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