scholarly journals Smoking cessation is associated with decreased mortality and improved amputation-free survival among patients with symptomatic peripheral artery disease

2014 ◽  
Vol 60 (6) ◽  
pp. 1565-1571 ◽  
Author(s):  
Ehrin J. Armstrong ◽  
Julie Wu ◽  
Gagan D. Singh ◽  
David L. Dawson ◽  
William C. Pevec ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Free Survival ◽  
Artery Disease

scholarly journals Smoking, Smoking Cessation, and Risk for Symptomatic Peripheral Artery Disease in Women

2011 ◽  
Vol 154 (11) ◽  
pp. 719 ◽  
Author(s):  
David Conen ◽  
Brendan M. Everett ◽  
Tobias Kurth ◽  
Mark A. Creager ◽  
Julie E. Buring ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Artery Disease

Propensity-matched analysis does not support angiosome-guided revascularization of multilevel peripheral artery disease (PAD)

2021 ◽  
pp. 1358863X2110386
Author(s):  
Pavel Kurianov ◽  
Alexandr Lipin ◽  
Alexey Antropov ◽  
Kirill Atmadzas ◽  
Nikita Gruzdev ◽  
...  
Keyword(s):  
Cohort Study ◽  
Peripheral Artery Disease ◽  
Healing Rate ◽  
Tissue Loss ◽  
Peripheral Artery ◽  
Free Survival ◽  
Line Flow ◽  
Comparative Cohort Study ◽  
Indirect Revascularization ◽  
Artery Disease

Background: This retrospective comparative cohort study evaluated the clinical outcome of angiosome-guided endovascular arterial reconstructions in chronic limb-threatening ischemia (CLTI) due to multilevel peripheral artery disease (PAD). Methods: Patients treated in an endovascular fashion for CLTI with tissue loss due to multilevel PAD were analyzed. Limbs were classified as having undergone either angiosome-guided (direct) revascularization (DR) or nonangiosomic (indirect) revascularization (IR). DR was defined as uninterrupted in-line flow to the affected angiosome, revascularization through the pedal arch was also considered direct. Groups were adjusted with propensity score (PS) matching and compared for amputation-free survival (AFS), freedom from major adverse limb events (MALE), and healing rate at 12 months. Results: A total of 174 patients (81 men, mean age 70.0 ± 10.4 y) were included. PS matching produced two groups of 55 patients each: DR (24 men, mean age 71.7 ± 10.7 y) and IR (26 men, mean age 72.0 ± 9.4 y). The matched groups had no significant differences in baseline variables. At 12 months there were no significant differences in AFS (73.2% vs 71.6%; p = 0.841), freedom from MALE (71.7% vs 66.1%; p = 0.617), and healing rate (72.7% vs 72.0%; p = 1.000) between DR and IR, respectively. Conclusion: This study failed to support the use of angiosome concept in CLTI due to multilevel disease.

Geriatric nutritional risk index (GNRI) predicts long-term survival and limb events in patients with peripheral artery disease

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
M Horiguchi ◽  
H Yamagishi ◽  
K Unno ◽  
T Takamura ◽  
K Tone ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Risk Index ◽  
Nutritional Risk ◽  
Geriatric Nutritional Risk Index ◽  
Peripheral Artery ◽  
Free Survival ◽  
Kaplan Meier ◽  
Nutritional Risk Index ◽  
Artery Disease

Abstract Background Geriatric nutritional risk index (GNRI) was developed as a “nutrition-related” risk index and was reported in different populations as associated with the risk of all-cause and cardiovascular morbidity and mortality. Purpose The purpose of this study was to assess the associations of GNRI with mortality and amputation free survival in patients with peripheral artery disease (PAD). Methods From January 2011 to June 2016, 295 consecutive patients (73.3±9.2 years; 75.6% male) with PAD undergoing endovascular treatment (EVT) in our hospital were retrospectively examined. The GNRI on admission was calculated as follows: 14.89 × serum albumin (g/dl) + 41.7 × body mass index (BMI)/22. Characteristics and mortality were compared between 2 groups: low GNRI (<92, n=110) with moderate or severe nutritional risk; and high GNRI (≥92, n=185) with no or low nutritional risk. Results The median follow up period was 39.4±26.4months. There were 85 deaths (28.8%) and 13 major amputation (4.4%) during the follow-up. Patients in the low-GNRI group were more often higher age, non-ambulatory state, hemodialysis and critical limb ischemia. BMI, serum hemoglobin, albumin, low-density lipoprotein were significantly lower, whereas serum C-reactive protein was significantly higher in the low-GNRI group than the high-GNRI group (P<0.05, respectively). Kaplan–Meier analysis revealed that patients in the low-GNRI group had a significantly lower amputation free survival, compared to those in the high-GNRI group (log-rank test, P<0.001). Conclusion The low GNRI is associated with an increased risk of mortality and limb events in patients with PAD. Amputation-free survival (Kaplan-Meier) Funding Acknowledgement Type of funding source: None

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