scholarly journals Data on amputation free survival of patients with lower limb peripheral artery disease classified according TASC II classification and a new crural index

Data in Brief ◽  
2016 ◽  
Vol 8 ◽  
pp. 242-246 ◽  
Author(s):  
Juho M. Jalkanen ◽  
Jan-Erik Wickström ◽  
Maarit Venermo ◽  
Harri H. Hakovirta
Keyword(s):  
Peripheral Artery Disease ◽  
Lower Limb ◽  
Peripheral Artery ◽  
Free Survival ◽  
Artery Disease

scholarly journals Plasma concentrations of lipoproteins and risk of lower-limb peripheral artery disease in people with type 2 diabetes: the SURDIAGENE study

Diabetologia ◽  
2021 ◽  
Vol 64 (3) ◽  
pp. 668-680
Author(s):  
Capucine Bertrand ◽  
◽  
Pierre-Jean Saulnier ◽  
Louis Potier ◽  
Mikaël Croyal ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Peripheral Artery Disease ◽  
Lower Limb ◽  
Plasma Concentrations ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Smoking cessation is associated with decreased mortality and improved amputation-free survival among patients with symptomatic peripheral artery disease

2014 ◽  
Vol 60 (6) ◽  
pp. 1565-1571 ◽  
Author(s):  
Ehrin J. Armstrong ◽  
Julie Wu ◽  
Gagan D. Singh ◽  
David L. Dawson ◽  
William C. Pevec ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Free Survival ◽  
Artery Disease

scholarly journals Lower Limb Amputations in Patients With Diabetes and Peripheral Artery Disease: A Time-Series Analysis of Trends (2005-2016)

2018 ◽  
Vol 68 (3) ◽  
pp. e83-e84
Author(s):  
Mohamad A. Hussain ◽  
Mohammed Al-Omran ◽  
Konrad Salata ◽  
Jack V. Tu ◽  
Atul Sivaswamy ◽  
...  
Keyword(s):  
Time Series ◽  
Time Series Analysis ◽  
Peripheral Artery Disease ◽  
Lower Limb ◽  
Peripheral Artery ◽  
Series Analysis ◽  
Patients With Diabetes ◽  
Artery Disease

Abstract MP14: Proteinuria is Associated With a Greater Risk of Lower Limb Amputation in Patients With Peripheral Artery Disease

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Jung-Im Shin ◽  
Morgan Grams ◽  
Josef Coresh ◽  
Alex Chang ◽  
Kunihiro Matsushita
Keyword(s):  
Peripheral Artery Disease ◽  
Lower Limb ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Lower Limb Amputation ◽  
Limb Amputation ◽  
Antiplatelet Drug ◽  
Peripheral Artery ◽  
Increased Risk ◽  
Artery Disease

Introduction: Proteinuria is shown to be associated with increased risk of peripheral artery disease (PAD). However, its association with the risk of lower limb amputation in patients with PAD is unknown. Hypothesis: We hypothesized that proteinuria is associated with the risk of amputation in patients with PAD in a graded fashion. Methods: We identified 3,388 PAD patients with data on urine dipstick proteinuria within two years prior to PAD diagnosis between 1997 and 2017 in the Geisinger Health System (mean age 69.7 years, 44.8% female, 97.4% non-Hispanic White, 57.8% diabetic). We quantified the association of proteinuria with the risk of amputation using Cox proportional hazards models, adjusting for demographics, calendar year, estimated glomerular filtration rate, HbA1c, comorbidities including diabetic retinopathy/neuropathy, and medication use (antiplatelet drug, statin, and renin-angiotensin system inhibitor). Results: There were 55.2% with negative dipstick proteinuria, 11.1% trace, 14.1% with 1+, and 19.5% with ≥2+. A total of 245 patients underwent amputations over a median follow-up of 3.4 years. Incidence rate of amputation was 1.15 per 100 person-years for dipstick negative, 1.47 for trace, 2.11 for 1+, and 3.78 for ≥2+. This dose-response relationship remained similar even after accounting for potential confounders (p-trend=0.015), with particularly evident association for ≥2+ of dipstick (an adjusted hazard ratio of 1.52 [95% confidence interval: 1.08-2.17, p=0.017) (Figure). When we added proteinuria to other covariates, the risk discrimination slightly improved (Δc-statistic 0.007 [0.001-0.014]). Conclusions: Higher proteinuria was associated with a greater risk of lower limb amputation among patients with newly diagnosed PAD. Our results suggest the importance of considering proteinuria in risk assessment of limb loss in PAD patients.

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