Two new organic–inorganic hybrid compounds based on metal–pyrazine coordination polymers and Keggin polyoxometalates: effect of metal ions on thestructure

2010 ◽  
Vol 183 (12) ◽  
pp. 2925-2931 ◽  
Author(s):  
Feng-Yun Cui ◽  
Xiao-Yu Ma ◽  
Cong Li ◽  
Tao Dong ◽  
Yuan-Zhe Gao ◽  
...  
Keyword(s):  
Metal Ions ◽  
Coordination Polymers ◽  
Inorganic Hybrid ◽  
Hybrid Compounds

Two new Keggin-type polyoxometalate-based organic-inorganic hybrid compounds with metal ions and chelate ligands

2017 ◽  
Vol 70 (7) ◽  
pp. 1156-1167 ◽  
Author(s):  
Shi-Fang Jia ◽  
Xiu-Li Hao ◽  
Yuan-Yuan Ma ◽  
Hong-Yi Wang ◽  
Yang-Guang Li
Keyword(s):  
Metal Ions ◽  
Inorganic Hybrid ◽  
Hybrid Compounds ◽  
Keggin Type ◽  
Chelate Ligands

Syntheses and Structures of Organic−Inorganic Hybrid Compounds Based on Metal−Fluconazole Coordination Polymers and the β-Mo8O26Anion

2007 ◽  
Vol 46 (20) ◽  
pp. 8283-8290 ◽  
Author(s):  
Li ◽  
Ya-Qian Lan ◽  
Jian-Fang Ma ◽  
Jin Yang ◽  
Xiao-Hong Wang ◽  
...  
Keyword(s):  
Coordination Polymers ◽  
Inorganic Hybrid ◽  
Hybrid Compounds

Metal-organic Nanopharmaceuticals

2020 ◽  
Vol 8 (3) ◽  
pp. 163-190
Author(s):  
Benjamin Steinborn ◽  
Ulrich Lächelt
Keyword(s):  
Metal Ions ◽  
Coordination Polymers ◽  
Active Agent ◽  
Lewis Base ◽  
High Loading ◽  
Active Components ◽  
Base Functions ◽  
Metal Organic ◽  
Theranostic Applications ◽  
Pharmacologically Active

: Coordinative interactions between multivalent metal ions and drug derivatives with Lewis base functions give rise to nanoscale coordination polymers (NCPs) as delivery systems. As the pharmacologically active agent constitutes a main building block of the nanomaterial, the resulting drug loadings are typically very high. By additionally selecting metal ions with favorable pharmacological or physicochemical properties, the obtained NCPs are predominantly composed of active components which serve individual purposes, such as pharmacotherapy, photosensitization, multimodal imaging, chemodynamic therapy or radiosensitization. By this approach, the assembly of drug molecules into NCPs modulates pharmacokinetics, combines pharmacological drug action with specific characteristics of metal components and provides a strategy to generate tailorable multifunctional nanoparticles. This article reviews different applications and recent examples of such highly functional nanopharmaceuticals with a high ‘material economy’. : Lay Summary: Nanoparticles, that are small enough to circulate in the bloodstream and can carry cargo molecules, such as drugs, imaging or contrast agents, are attractive materials for pharmaceutical applications. A high loading capacity is a generally aspired parameter of nanopharmaceuticals to minimize patient exposure to unnecessary nanomaterial. Pharmaceutical agents containing Lewis base functions in their molecular structure can directly be assembled into metal-organic nanopharmaceuticals by coordinative interaction with metal ions. Such coordination polymers generally feature extraordinarily high loading capacities and the flexibility to encapsulate different agents for a simultaneous delivery in combination therapy or ‘theranostic’ applications.

scholarly journals Enzyme-Loaded Flower-Shaped Nanomaterials: A Versatile Platform with Biosensing, Biocatalytic, and Environmental Promise

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1460
Author(s):  
Khadega A. Al-Maqdi ◽  
Muhammad Bilal ◽  
Ahmed Alzamly ◽  
Hafiz M. N. Iqbal ◽  
Iltaf Shah ◽  
...  
Keyword(s):  
Organic Matter ◽  
Metal Ions ◽  
Critical Points ◽  
Structural Integrity ◽  
Early Stage ◽  
Surface Orientation ◽  
Critical Factors ◽  
Inorganic Hybrid ◽  
Iron Based ◽  
Significant Attention

As a result of their unique structural and multifunctional characteristics, organic–inorganic hybrid nanoflowers (hNFs), a newly developed class of flower-like, well-structured and well-oriented materials has gained significant attention. The structural attributes along with the surface-engineered functional entities of hNFs, e.g., their size, shape, surface orientation, structural integrity, stability under reactive environments, enzyme stabilizing capability, and organic–inorganic ratio, all significantly contribute to and determine their applications. Although hNFs are still in their infancy and in the early stage of robust development, the recent hike in biotechnology at large and nanotechnology in particular is making hNFs a versatile platform for constructing enzyme-loaded/immobilized structures for different applications. For instance, detection- and sensing-based applications, environmental- and sustainability-based applications, and biocatalytic and biotransformation applications are of supreme interest. Considering the above points, herein we reviewed current advances in multifunctional hNFs, with particular emphasis on (1) critical factors, (2) different metal/non-metal-based synthesizing processes (i.e., (i) copper-based hNFs, (ii) calcium-based hNFs, (iii) manganese-based hNFs, (iv) zinc-based hNFs, (v) cobalt-based hNFs, (vi) iron-based hNFs, (vii) multi-metal-based hNFs, and (viii) non-metal-based hNFs), and (3) their applications. Moreover, the interfacial mechanism involved in hNF development is also discussed considering the following three critical points: (1) the combination of metal ions and organic matter, (2) petal formation, and (3) the generation of hNFs. In summary, the literature given herein could be used to engineer hNFs for multipurpose applications in the biosensing, biocatalysis, and other environmental sectors.

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