Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric β-neurotoxin

2019 ◽  
Vol 192 ◽  
pp. 196-207 ◽  
Author(s):  
Edgar Neri-Castro ◽  
Bruno Lomonte ◽  
Mariel Valdés ◽  
Roberto Ponce-López ◽  
Melisa Bénard-Valle ◽  
...  
Keyword(s):  
Proteomic Profiling

Proteomic Profiling and Functional Characterization of Multiple Post-Translational Modifications of Tubulin

2015 ◽  
Vol 14 (8) ◽  
pp. 3292-3304 ◽  
Author(s):  
Ningning Liu ◽  
Yun Xiong ◽  
Yiran Ren ◽  
Linlin Zhang ◽  
Xianfei He ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Proteomic Profiling ◽  
Post Translational Modifications

Proteomic profiling between CNE-2 and its strongly metastatic subclone S-18 and functional characterization of HSP27 in metastasis of nasopharyngeal carcinoma

PROTEOMICS ◽  
2011 ◽  
Vol 11 (14) ◽  
pp. 2911-2920 ◽  
Author(s):  
Guo-Ping Li ◽  
Hua Wang ◽  
Yiu-Kay Lai ◽  
Shao-Chun Chen ◽  
Marie C. M. Lin ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Functional Characterization ◽  
Proteomic Profiling

Proteomic profiling and characterization of differential allergens in the nematodes Anisakis simplex sensu stricto and A. pegreffii

PROTEOMICS ◽  
2014 ◽  
Vol 14 (12) ◽  
pp. 1547-1568 ◽  
Author(s):  
Susana C. Arcos ◽  
Sergio Ciordia ◽  
Lee Roberston ◽  
Inés Zapico ◽  
Yolanda Jiménez-Ruiz ◽  
...  
Keyword(s):  
Sensu Stricto ◽  
Anisakis Simplex ◽  
Proteomic Profiling

scholarly journals Proteomic profiling of the endogenous peptides of MRSA and MSSA

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12508
Author(s):  
Haixia Tu ◽  
Fei Xu ◽  
Yiwei Cheng ◽  
Qianglong Pan ◽  
Xiao Cai ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Metabolic Regulation ◽  
Proteomic Profiling ◽  
Positive Bacterium ◽  
Future Studies ◽  
Endogenous Peptides ◽  
C Terminus ◽  
Severe Infections ◽  
Functional Regulation

Staphylococcus aureus is a Gram-positive bacterium that can cause diverse skin and soft tissue infections. Methicillin-resistant Staphylococcus aureus (MRSA) can cause more severe infections than methicillin-susceptible Staphylococcus aureus (MSSA). Nevertheless, the physiological and metabolic regulation of MSSA and MRSA has not been well studied. In light of the increased interest in endogenous peptides and recognition of the important roles that they play, we studied the endogenous peptidome of MSSA and MRSA. We identified 1,065 endogenous peptides, among which 435 were differentially expressed (DE), with 292 MSSA-abundant endogenous peptides and 35 MRSA-abundant endogenous peptides. MSSA-abundant endogenous peptides have significantly enriched “VXXXK” motif of at the C-terminus. MSSA-abundant endogenous peptides are involved in penicillin-binding and immune responses, whereas MRSA-abundant endogenous peptides are associated with antibiotic resistance and increased toxicity. Our characterization of the peptidome of MSSA and MRSA provides a rich resource for future studies to explore the functional regulation of drug resistance in S. aureus and may also help elucidate the mechanisms of its pathogenicity and the development of treatments.

Proteomic Profiling of Breast Tissue Collagens and Site-specific Characterization of Hydroxyproline Residues of Collagen Alpha-1-(I)

2012 ◽  
Vol 11 (12) ◽  
pp. 5890-5902 ◽  
Author(s):  
Helen Montgomery ◽  
Nitin Rustogi ◽  
Andreas Hadjisavvas ◽  
Koichi Tanaka ◽  
Kyriacos Kyriacou ◽  
...  
Keyword(s):  
Breast Tissue ◽  
Proteomic Profiling ◽  
Site Specific

scholarly journals Proteomic profiling and functional characterization of early and late shoulder osteoarthritis

2013 ◽  
Vol 15 (6) ◽  
pp. R180 ◽  
Author(s):  
John Wanner ◽  
Roopashree Subbaiah ◽  
Yelenna Skomorovska-Prokvolit ◽  
Yousef Shishani ◽  
Eric Boilard ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Proteomic Profiling ◽  
Shoulder Osteoarthritis
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