scholarly journals Outcome of therapeutic penetrating keratoplasty in advanced infectious keratitis

2018 ◽  
Vol 30 (4) ◽  
pp. 315-320 ◽  
Author(s):  
Anuradha Raj ◽  
Harsh Bahadur ◽  
Renu Dhasmana
Keyword(s):  
Penetrating Keratoplasty ◽  
Infectious Keratitis ◽  
Therapeutic Penetrating Keratoplasty

scholarly journals The Incidence and Outcomes of Recurrence of Infection after Therapeutic Penetrating Keratoplasty for Medically-Uncontrolled Infectious Keratitis

2020 ◽  
Vol 9 (11) ◽  
pp. 3696
Author(s):  
Jayoon Moon ◽  
Chang Ho Yoon ◽  
Mee Kum Kim ◽  
Joo Youn Oh
Keyword(s):  
Penetrating Keratoplasty ◽  
Positive Culture ◽  
Primary Outcome Measure ◽  
Close Monitoring ◽  
Infectious Keratitis ◽  
Tertiary Referral Center ◽  
Included Patient ◽  
Operative Findings ◽  
Therapeutic Penetrating Keratoplasty ◽  
Infection Recurrence

Background: This study aimed to investigate the outcome of therapeutic penetrating keratoplasty (TPK) for medically-uncontrolled infectious keratitis, and to determine the factors associated with the recurrence of infection after TPK. Methods: A 10-year retrospective study of medically-uncontrolled infectious keratitis with positive culture results, who received TPK at a tertiary referral center in Korea was performed. Data collection included patient demographics, medical history, pre- and post-operative findings, surgical procedures, causative microorganisms, and visual acuities (VA). The primary outcome measure was the recurrence of infection after TPK, and the factors were compared between patients with and without recurrence. Results: A total of 19 patients (19 eyes) were analyzed, of which 6 eyes (31.6%) had infection recurrence at 21.6 ± 22.84 months after TPK. Recurrence occurred more frequently in the female sex (vs. male, p = 0.013) and in longer duration (>30 days) from infection onset to TPK (vs. ≤30 days, p = 0.025). Final best-corrected-VA was poorer in patients with recurrence than those without (LogMAR 1.60 ± 0.97 vs. 2.40 ± 0.46, p = 0.026). Evisceration was performed in 2 out of 6 patients with recurrence (33.3%), while none was performed in those without recurrence (p = 0.028). Conclusion: Infection recurrence after TPK was 31.6%. Given the poor outcome of TPK in eyes with recurrence, close monitoring and intensive treatment are required post-TPK.

Outcome of Therapeutic Penetrating Keratoplasty Using Glycerol-Preserved Donor Corneas in Infectious Keratitis

Cornea ◽  
2016 ◽  
Vol 35 (9) ◽  
pp. 1175-1178 ◽  
Author(s):  
Onsiri Thanathanee ◽  
Wathanee Sripawadkul ◽  
Orapin Anutarapongpan ◽  
Patanaree Luanratanakorn ◽  
Olan Suwan-Apichon
Keyword(s):  
Penetrating Keratoplasty ◽  
Infectious Keratitis ◽  
Therapeutic Penetrating Keratoplasty ◽  
Donor Corneas
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