Stable bellows cup electrode demonstrates low-frequency properties of long-term electroretinographic recordings in the Limulus lateral eye

2007 ◽  
Vol 159 (2) ◽  
pp. 252-260 ◽  
Author(s):  
Amanda R. Bolbecker ◽  
Adrienne R. Lewis ◽  
Alicia A. Swan ◽  
Kenneth Carlson ◽  
Jennifer R. Fleet ◽  
...  
Author(s):  
Tong Wu ◽  
Guoliang Yu ◽  
Jiarui Pang ◽  
Can Wang ◽  
Han Yang ◽  
...  

This work presents an easy way to improve the low-frequency properties in a small-size LTE/WWAN smartphone antenna by just loading a soft magnetic ferrite film on the strong radiation area. The base non-magnetic antenna, which only takes up an 11 mm × 30 mm no-ground space, can achieve hexa-band operation covering 822–914/1710–3244 MHz bands by co-designing a meandering strip and a T-shaped feeding strip. With loading a small-size ferrite film (2 mm × 15 mm) at the strong radiation strip, the frequencies can be shifted to cover the range of 692–1191/1698–3020 MHz, which shows a fully covering of octa-band operation, especially including the best long-term-evolution band, LTE700, without enlarging the size of base antenna. In addition, the radiation characteristics of the magnetic antenna with ferrite film loading show a limited change at upper bands (1710–2690 MHz) but an acceptable level at lower bands (698–960 MHz). Both experimental and simulated results have been taken out and shown the consistent tendency. This optimization method of low-frequency properties by introducing a commercial ferrite film on the antenna has provided a simple and convenient way to solve the frequency deviation in the practical smartphone applications.


2014 ◽  
Vol 7 (6) ◽  
pp. 914-916 ◽  
Author(s):  
Didier Clarençon ◽  
Sonia Pellissier ◽  
Valérie Sinniger ◽  
Astrid Kibleur ◽  
Dominique Hoffman ◽  
...  

1991 ◽  
Vol 65 (1) ◽  
pp. 20-32 ◽  
Author(s):  
Y. Komatsu ◽  
S. Nakajima ◽  
K. Toyama

1. Intracellular recording was made from layer II-III cells in slice preparations of kitten (30-40 days old) visual cortex. Low-frequency (0.1 Hz) stimulation of white matter (WM) usually evoked an excitatory postsynaptic potential (EPSP) followed by an inhibitory postsynaptic potential (IPSP). The postsynaptic potentials (PSPs) showed strong dependence on stimulus frequency. Early component of EPSP and IPSP evoked by weak stimulation both decreased monotonically at frequencies greater than 0.5-1 Hz. Strong stimulation similarly depressed the early EPSP at higher frequencies (greater than 2 Hz) and replaced the IPSP with a late EPSP, which had a maximum amplitude in the stimulus frequency range of 2-5 Hz. 2. Very weak WM stimulation sometimes evoked EPSPs in isolation from IPSPs. The falling phase of the EPSP revealed voltage dependence characteristic to the responses mediated by N-methyl-D-aspartate (NMDA) receptors and was depressed by application of an NMDA antagonist DL-2-amino-5-phosphonovalerate (APV), whereas the rising phase of the EPSP was insensitive to APV. 3. The early EPSPs followed by IPSPs were insensitive to APV but were replaced with a slow depolarizing potential by application of a non-NMDA antagonist 6,7-dinitro-quinoxaline-2,3-dione (DNQX), indicating that the early EPSP is mediated by non-NMDA receptors. The slow depolarization was mediated by NMDA receptors because it was depressed by membrane hyperpolarization or addition of APV. 4. The late EPSP evoked by higher-frequency stimulation was abolished by APV, indicating that it is mediated by NMDA receptors, which are located either on the recorded cell or on presynaptic cells to the recorded cells. 5. Long-term potentiation (LTP) of EPSPs was examined in cells perfused with solutions containing 1 microM bicuculline methiodide (BIM), a gamma-aminobutyric acid (GABA) antagonist. WM was stimulated at 2 Hz for 15 min as a conditioning stimulus to induce LTP, and the resultant changes were tested by low-frequency (0.1 Hz) stimulation of WM. 6. LTP of early EPSPs occurred in more than one-half of the cells (8/13) after strong conditioning stimulation. The rising slope of the EPSP was increased 1.6 times on average. 7. To test involvement of NMDA receptors in the induction of LTP in the early EPSP, the effect of conditioning stimulation was studied in a solution containing 100 microM APV, which was sufficient to block completely synaptic transmission mediated by NMDA receptors. LTP occurred in the same frequency and magnitude as in control solution.


2008 ◽  
Vol 21 (9) ◽  
pp. 1948-1962 ◽  
Author(s):  
R. Garcia-Herrera ◽  
D. Barriopedro ◽  
E. Hernández ◽  
H. F. Diaz ◽  
R. R. Garcia ◽  
...  

Abstract The authors present a chronology of El Niño (EN) events based on documentary records from northern Peru. The chronology, which covers the period 1550–1900, is constructed mainly from primary sources from the city of Trujillo (Peru), the Archivo General de Indias in Seville (Spain), and the Archivo General de la Nación in Lima (Peru), supplemented by a reassessment of documentary evidence included in previously published literature. The archive in Trujillo has never been systematically evaluated for information related to the occurrence of El Niño–Southern Oscillation (ENSO). Abundant rainfall and river discharge correlate well with EN events in the area around Trujillo, which is very dry during most other years. Thus, rain and flooding descriptors, together with reports of failure of the local fishery, are the main indicators of EN occurrence that the authors have searched for in the documents. A total of 59 EN years are identified in this work. This chronology is compared with the two main previous documentary EN chronologies and with ENSO indicators derived from proxy data other than documentary sources. Overall, the seventeenth century appears to be the least active EN period, while the 1620s, 1720s, 1810s, and 1870s are the most active decades. The results herein reveal long-term fluctuations in warm ENSO activity that compare reasonably well with low-frequency variability deduced from other proxy data.


Author(s):  
Neil Bates ◽  
David Lee ◽  
Clifford Maier

This paper describes case studies involving crack detection in-line inspections and fitness for service assessments that were performed based on the inspection data. The assessments were used to evaluate the immediate integrity of the pipeline based on the reported features and the long-term integrity of the pipeline based on excavation data and probabilistic SCC and fatigue crack growth simulations. Two different case studies are analyzed, which illustrate how the data from an ultrasonic crack tool inspection was used to assess threats such as low frequency electrical resistance weld seam defects and stress corrosion cracking. Specific issues, such as probability of detection/identification and the length/depth accuracy of the tool, were evaluated to determine the suitability of the tool to accurately classify and size different types of defects. The long term assessment is based on the Monte Carlo method [1], where the material properties, pipeline details, crack growth parameters, and feature dimensions are randomly selected from certain specified probability distributions to determine the probability of failure versus time for the pipeline segment. The distributions of unreported crack-related features from the excavation program are used to distribute unreported features along the pipeline. Simulated crack growth by fatigue, SCC, or a combination of the two is performed until failure by either leak or rupture is predicted. The probability of failure calculation is performed through a number of crack growth simulations for each of the reported and unreported features and tallying their respective remaining lives. The results of the probabilistic analysis were used to determine the most effective and economical means of remediation by identifying areas or crack mechanisms that contribute most to the probability of failure.


2009 ◽  
Vol 136 (5) ◽  
pp. A-20
Author(s):  
Judith E. Baars ◽  
Ernst J. Kuipers ◽  
Ruud Beukers ◽  
Adriaan C. Tan ◽  
Bas L. Weusten ◽  
...  

1996 ◽  
Vol 75 (2) ◽  
pp. 877-884 ◽  
Author(s):  
P. T. Huerta ◽  
J. E. Lisman

1. The induction of long-term weakening of synaptic transmission in rat hippocampal slices was examined in CA1 synapses during cholinergic modulation. 2. Bath application of the cholinergic agonist carbachol (50 microM) activated an oscillation of the local field potential in the theta-frequency range (5-12 Hz), termed theta. It was previously shown that a stimulation train of 40 single shocks (at 0.1 Hz) to the Schaffer collateral-commisural afferents, each synchronized with positive peaks of theta, caused homosynaptic long-term enhancement in CA1. Furthermore, long-term depression (LTD) was sporadically observed when the stimulation train was given at negative troughs of theta. Here we have sought to determine stable conditions for LTD induction during theta. 3. Synaptic weakening was reliably obtained, by giving 40 shocks (at 0.1 Hz) at theta-troughs, only in pathways that had been previously potentiated. This decrement, termed theta-LTD, was synapse specific because it did not occur in an independent pathway not stimulated during theta. The interval between the initial potentiating tetanus and theta-LTD induction could be as long as 90 min. 4. theta-LTD could be saturated; after consecutive episodes of theta-LTD induction, no significant further depression was obtained. Moreover, theta-LTD could be reversed by tetanic stimulation. 5. theta-LTD could prevent the induction of LTD by 600-900 pulses at 1 Hz. This suggests that the two protocols may share common mechanisms at the synaptic level. 6. We conclude that single presynaptic spikes that occur at low frequency and are properly timed to the troughs of theta may be a relevant mechanism for decreasing the strength of potentiated synapses.


Author(s):  
Aaron Dinovitzer ◽  
Sanjay Tiku ◽  
Vlado Semiga ◽  
Abdelfettah Fredj ◽  
Joe Zhou ◽  
...  

While the formation of a wrinkle in an onshore pipeline is an undesirable event, in many instances this event does not have immediate pipeline integrity implications. The magnitude or severity of a wrinkle formed due to displacement controlled loading processes (e.g. slope movement, fault displacement, frost heave and thaw settlement) may increase with time, eventually causing serviceability concerns (e.g. fluid flow or inspection restrictions). Pipe wall damage leading to cracking and eventually a loss of containment involves contributions from the wrinkle formation and growth processes, as well as, wrinkle deformations promoted by in-service line pressure, temperature and seasonal soil displacements. The objective of this paper is to provide an overview of the ongoing research efforts, sponsored by TransCanada PipeLines Ltd. and Tokyo Gas Co. Ltd., towards the development of a mechanics based wrinkle ultimate limits state that may be used in future to evaluate the long term integrity of wrinkled pipeline segments. The research efforts include non-linear finite element modeling to demonstrate the ability of experimentally derived material properties to predict the formation of through wall cracking induced by high and low frequency load effects. This paper outlines the material testing program used to support the development of failure criteria capable of considering the contributions of monotonic deformation, as well as, high and low cycle cyclic loading.


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