scholarly journals Knowledge, perceptions, and environmental risk factors among Jamaican households with a history of leptospirosis

2014 ◽  
Vol 7 (4) ◽  
pp. 314-322 ◽  
Author(s):  
Paul Allwood ◽  
Claudia Muñoz-Zanzi ◽  
Martin Chang ◽  
Paul D. Brown
Keyword(s):  
Risk Factors ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
History Of

scholarly journals Mapping And Analysis of Environmental Risk Factors Leptospirosis Incidence Based Geographic Information System (GIS) In Sampang Regency

2016 ◽  
Vol 8 (1) ◽  
pp. 48
Author(s):  
Annisa Rahim ◽  
Ririh Yudhastuti
Keyword(s):  
Risk Factors ◽  
Environmental Risk ◽  
Cross Sectional Study ◽  
Environmental Risk Factors ◽  
Sectional Study ◽  
Cross Sectional ◽  
Unit Of Analysis ◽  
Incidence Risk ◽  
History Of ◽  
Observational Descriptive Study

Abstract: One  of the  zoonosis in Indonesia is leptospirosis. Leptospirosis is caused due  to infection  of bacteria Leptospira. There  were  107 cases and  9 deaths due  to leptospirosis in Sampang. The  incidence of leptospirosis in Sampang was an outbreak. The purpose of this study  was to map the distribution  of leptospirosis cases in Sampang in 2013 and to analyze environmental risk factors of leptospirosis cases (rainfall, altitude, and the presence of flood). This study  was an observational-descriptive study  and used cross-sectional study  design. The unit of analysis  of the study was administrative  regions  based on the districts.  There was patients  of leptospirosis in 4 districts in Sampang regency, there are Sampang district, Camplong district Robatal district and Omben district. The highest incidence of leptospirosis in Sampang regency was occured in Sampang district with rainfall more than 177.6 mm,  altitude less  than 47mdpl, and had experienced flooding.  Mapping  the incidence of leptospirosis showed the distribution  of leptospirosis cases tend to be  concentrated in Sampang district which  had a history of flooding  status.  The conclusion is rainfall, altitude, and presence of flood are risk factors  of leptospirosis. The advice is to improve  surveillance of patients  with leptospirosis particularly during floods,  to do outreach to the community, to perform cross-sector cooperation, to avoid or to reduce the frequency of direct contact with the flood to minimize  transmission of leptospirosis.Keywords: leptospirosis incidence, risk factors,  mapping

Genetic and environmental risk factors in the aetiology of illicit drug initiation and subsequent misuse in women

1999 ◽  
Vol 175 (4) ◽  
pp. 351-356 ◽  
Author(s):  
Kenneth S. Kendler ◽  
Laura M. Karkowski ◽  
Linda A. Corey ◽  
Carol A. Prescott ◽  
Michael C. Neale
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Family Environment ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
Psychoactive Substance ◽  
Psychoactive Substances ◽  
Initial Exposure ◽  
History Of ◽  
The Individual

BackgroundSubsequent to initial exposure to the use of a psychoactive substance, psychoactive substance use disorder (PSUD) may or may not develop.AimsTo investigate the relationship between the risk factors for initiation and the subsequent misuse of psychoactive substances.MethodThe lifetime history of illicit substance use and misuse was obtained by telephone interview with 1934 members of female–female twin pairs. We apply a novel model, which estimates the role of genetic and environmental risk factors that influence initiation and those specific to misuse, to three classes of illicit psychoactive substances.ResultsThe individual-specific environment and family environment influenced the probability of initiation, but only individual-specific environment had an impact on the probability of subsequent misuse. Genetic factors which influence the risk of initiation and of misuse were identified.ConclusionsAetiological factors that influence drug initiation and subsequent misuse are correlated but not identical. Family environment is an important determinant of risk for drug experimentation. Two classes of genetic risk factors act on the liability to PSUD: those that influence the probability of initiation and those that influence the risk of misuse.

Risk of EBV-Positive Hodgkin Lymphoma Varies Over 30-Fold by HLA Class I Genotype and History of Infectious Mononucleosis.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 269-269
Author(s):  
Ruth Jarrett ◽  
Paul CD Johnson ◽  
Klaus Rostgaard ◽  
Annette Lake ◽  
Lesley Shield ◽  
...  
Keyword(s):  
Risk Factors ◽  
Protective Effect ◽  
Hodgkin Lymphoma ◽  
Infectious Mononucleosis ◽  
Environmental Risk ◽  
Previous History ◽  
Hla Class I ◽  
Environmental Risk Factors ◽  
Class I ◽  
History Of

Abstract Abstract 269 Introduction: Markers in the human leukocyte antigen (HLA) class I locus and infectious mononucleosis (IM) have both been associated with Epstein-Barr (EBV)-positive Hodgkin lymphoma (HL). IM is caused by late infection with EBV. To further explore associations between HLA class I genes and EBV-positive HL and to investigate potential interactions between genetic (HLA) and environmental risk factors in the development of HL, we performed a case-only study of 934 HL cases. Methods: HLA-A and B typing were performed by PCR sequence specific oligonucleotide assay. Logistic regression was used to estimate odds ratios (ORs) of EBV-positive HL relative to EBV-negative HL for HLA-A and B genotypes and other known risk factors. Results: Increasing age, male sex, HLA-A*01 and a previous history of IM were all associated with a statistically significant increased odds of EBV-positive HL while HLA-A*02 and HLA-B*07 were associated with a protective effect. Significant interactions were detected between HLA-A*01 and HLA-B*07 and between prior IM and HLA-A*02, such that HLA-B*07 abolished the increased odds associated with HLA-A*01 and HLA-A*02 abrogated the increased odds associated with prior IM. In our final model of EBV-positive HL, HLA-B*07 was associated with a dominant protective effect (OR=0.57, 95% confidence interval (CI): 0.34–0.94); HLA-A*02 was associated with a protective effect which was additive (for individuals with no prior IM, ORper allele =0.69, 95% CI: 0.50–0.97); and HLA-A*01 was associated with an increased odds in patients who were HLA-B*07-negative (ORper allele=2.15, 95% CI: 1.54–3.01). Prior IM was independently associated with EBV-positive HL (OR=3.35, 95% CI: 1.67–6.73). This resulted in a >32-fold higher odds of EBV-positive HL in HLA-A*01 homozygotes with IM compared to HLA-A*02 homozygotes without IM. Conclusions: We have identified strong associations between both genetic and environmental risk factors and EBV-positive HL. Our findings suggest that HLA class I-restricted, cell-mediated responses to EBV and a prior history of IM play critical roles in the pathogenesis of EBV-positive HL. Disclosures: No relevant conflicts of interest to declare.

Self-Control As a Moderator for Environmental Risk Factors

2010 ◽  
Author(s):  
Thomas A. Wills ◽  
Pallav Pokhrel ◽  
Frederick X. Gibbons ◽  
James D. Sargent ◽  
Mike Stoolmiller
Keyword(s):  
Risk Factors ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
Self Control

Environmental Risk Factors in Multiple Sclerosis Questionnaire

2012 ◽  
Author(s):  
M. Pugliatti ◽  
I. Casetta ◽  
J. Drulovic ◽  
E. Granieri ◽  
T. Holmøy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multiple Sclerosis ◽  
Environmental Risk ◽  
Environmental Risk Factors

Genetic and Environmental Risk Factors for Alcoholism: A 16-Year Longitudinal Cohort Study

2019 ◽  
Author(s):  
I-Chao Liu ◽  
Shu-Fen Liao ◽  
Lawrence Shih-Hsin ◽  
Susan Shur-Fen Gau ◽  
Wen-Chung Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort
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