Nocardia paucivorans – A cause of disseminated Nocardiosis

2007 ◽  
Vol 54 (2) ◽  
pp. e95-e98 ◽  
Author(s):  
Timothy James Gray ◽  
David J. Serisier ◽  
Christopher M. Gilpin ◽  
Christopher Coulter ◽  
Simon J. Bowler ◽  
...  
Keyword(s):  
Disseminated Nocardiosis

Primary cutaneous nocardiosis of the head and neck in an immunocompetent patient

2021 ◽  
Vol 14 (5) ◽  
pp. e241217
Author(s):  
Claudio Tirso Acevedo ◽  
Frank Imkamp ◽  
Ewerton Marques Maggio ◽  
Silvio Daniel Brugger
Keyword(s):  
Head And Neck ◽  
Skin Lesions ◽  
Immunocompetent Patient ◽  
Rrna Gene ◽  
Gene Sequence Analysis ◽  
Rare Manifestation ◽  
Life Threatening ◽  
Amoxicillin Clavulanic Acid ◽  
Disseminated Nocardiosis ◽  
The Right

Nocardiosis is known to be an opportunistic infection most commonly affecting immunocompromised patients that can lead to life-threatening conditions. Primary cutaneous disease remains a rare manifestation and unlike pulmonary or disseminated nocardiosis, it usually affects immunocompetent individuals. We present a case of a primary cutaneous nocardiosis of the head and neck after an insect bite in a healthy 50-year-old woman who had recently travelled from Greece. She presented with a painful right-sided swelling of her face and neck and an ulcerated plaque over the right temple. Biopsy of the plaque revealed inflammation with abscess formation indicating underlying infection. Culture from the biopsy showed growth of Nocardia spp and 16S rRNA gene sequence analysis identified Nocardia brasiliensis. The patient was treated with trimethoprim/sulfamethoxazole and subsequently switched to amoxicillin/clavulanic acid due to a drug eruption. Antibiotic therapy was continued for a total of 3 months with complete resolution of the skin lesions.

scholarly journals Case report of disseminated nocardiosis during immunosppressive treatment

2010 ◽  
Vol 25 (1) ◽  
Author(s):  
Maria Teresa Gallo ◽  
Grazia Prignano ◽  
Pietro Donati ◽  
Elena Greco ◽  
Alan Di Maio ◽  
...  
Keyword(s):  
Case Report ◽  
Disseminated Nocardiosis

scholarly journals Disseminated nocardiosis in a patient with nephrotic syndrome following HIV infection

2014 ◽  
Vol 8 (4) ◽  
pp. 1142-1144 ◽  
Author(s):  
LETIAN ZHOU ◽  
HONG LIU ◽  
FANG YUAN ◽  
SHUGUANG YUAN
Keyword(s):  
Nephrotic Syndrome ◽  
Hiv Infection ◽  
Disseminated Nocardiosis

scholarly journals A Case of Disseminated Nocardiosis Secondary to the Skin Nodules in an Elderly Woman

2008 ◽  
Vol 20 (2) ◽  
pp. 82 ◽  
Author(s):  
Seung Gyun In ◽  
Sung Hyup Han ◽  
Jeong Hyun Shin ◽  
Gwang Seong Choi ◽  
Moon Hyun Chung
Keyword(s):  
Elderly Woman ◽  
Skin Nodules ◽  
Disseminated Nocardiosis

scholarly journals P1771NOCARDIOSIS IN RENAL TRANSPLANT RECIPIENTS- TEN YEARS OF SINGLE CENTER EXPERIENCE

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Ravi Kumar Singh ◽  
A K Bhalla ◽  
Anurag Gupta ◽  
Vinant Bhargava ◽  
Ashwani Gupta ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Antibiotic Sensitivity ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Sensitivity Testing ◽  
Nocardia Farcinica ◽  
Maldi Tof ◽  
Single Center Experience ◽  
First Line Therapy ◽  
Disseminated Nocardiosis

Abstract Background and Aims Nocardiosis is a localized or disseminated bacterial infection caused by aerobic Actinomyces that commonly affects immunocompromised hosts. This study aimed to retrospectively review the clinical course and outcome of nocardiosis in renal transplant recipients at our center Method Data was obtained from hospital records retrospectively. Sixteen cases of nocardiosis were identified in a series of more than 1800 consecutive renal transplants performed at Sir Ganga Ram Hospital in the last decade from the year 2010 to 2019. Results Thirteen out of Sixteen patients(81.25%) had developed nocardiosis within a 1-year post-renal transplant. The diabetic population constituted 31.3%. CMV disease was present in 25% of patients six months prior to the diagnosis of Nocardiosis.56.3% of patients were on Trimethoprim-sulfamethoxazole prophylaxis while they were diagnosed with nocardiosis. Pleuropulmonary nocardiosis was the most common form of infection(68.75%). Primary cutaneous nocardiosis was identified in one patient(6.25%). cerebral nocardiosis and disseminated nocardiosis was diagnosed in two patients each(12.5%).In the last 3 years with the introduction of MALDI-TOF led to the identification of the subspecies of Nocardia which was not possible earlier. In the last 3 years, 6 patients were diagnosed with nocardiosis, in which 4 were infected with Nocardia farcinica, one patient with Nocardia Asiatica and one with Nocardia cyrigeorgica. Nocardia farcinica was resistant to cotrimoxazole, which used to be first-line therapy against Nocardiosis before subspecies identification and sensitivity testing. With the help of proper identification of subspecies by MALDI-TOF and antibiotic susceptibility by E-testing, 5 out of 6 patients could be treated while earlier 6 out of 10 patients could be treated. Conclusion Nocardiosis is a rare, difficult-to-diagnose-and-treat infection following kidney transplantation. Trimethoprim-sulfamethoxazole prophylaxis was not effective in the prevention of disease. The Subspecies identification and modification of the plan of management according to antibiotic sensitivity results in improved outcomes.

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