Contribution of ferulic acid, γ-oryzanol and tocotrienols to the cardiometabolic protective effects of rice bran

2017 ◽  
Vol 32 ◽  
pp. 58-71 ◽  
Author(s):  
Cristina Perez-Ternero ◽  
Maria Alvarez de Sotomayor ◽  
Maria Dolores Herrera
Keyword(s):  
Ferulic Acid ◽  
Rice Bran ◽  
Protective Effects

scholarly journals Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production

2017 ◽  
Vol 8 (6) ◽  
pp. 2165-2174 ◽  
Author(s):  
Cristina Perez-Ternero ◽  
Alba Macià ◽  
Maria Alvarez de Sotomayor ◽  
Juan Parrado ◽  
Maria-Jose Motilva ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Ferulic Acid ◽  
Rice Bran ◽  
Superoxide Production ◽  
Enzymatic Extract

Rice bran is an exceptional source of such antioxidant molecules as γ-oryzanol and ferulic acid, but their bioavailability and metabolism within this matrix remain unknown.

Binary Solvent Extraction of Tocols, γ-Oryzanol, and Ferulic Acid from Rice Bran Using Alkaline Treatment Combined with Ultrasonication

2017 ◽  
Vol 65 (24) ◽  
pp. 4897-4904 ◽  
Author(s):  
Hoa Thi Truong ◽  
Phuong Duc Luu ◽  
Kiyoshi Imamura ◽  
Takeo Matsubara ◽  
Hideki Takahashi ◽  
...  
Keyword(s):  
Solvent Extraction ◽  
Ferulic Acid ◽  
Rice Bran ◽  
Alkaline Treatment ◽  
Binary Solvent

Biotransformation of Rice Bran to Ferulic Acid by Pediococcal Isolates

2013 ◽  
Vol 170 (4) ◽  
pp. 854-867 ◽  
Author(s):  
Baljinder Kaur ◽  
Debkumar Chakraborty ◽  
Gundeep Kaur ◽  
Gaganjot Kaur
Keyword(s):  
Ferulic Acid ◽  
Rice Bran

The ulcerogenic and protective action of rice and rice fractions in experimental peptic ulceration

1987 ◽  
Vol 72 (4) ◽  
pp. 463-466 ◽  
Author(s):  
A. P. Jayaraj ◽  
F. I. Tovey ◽  
C. G. Clark ◽  
K. R. Rees ◽  
J. S. White ◽  
...  
Keyword(s):  
Geographical Distribution ◽  
Rice Bran ◽  
Rice Bran Oil ◽  
Protective Action ◽  
Protective Effects ◽  
P Values ◽  
The World ◽  
Plausible Hypothesis ◽  
Ulcerogenic Effect ◽  
Ulcer Model

1. The ulcerogenic and protective effects of various rice fractions in the diet were studied in the pylorus ligated ulcer model in the rat. 2. Oil present in rice and particularly rice bran becomes ulcerogenic on storage and in this model results in a significant increase in the median (range) numbers of ulcers from six (one to ten) to nine (six to 15) (P > 0.05). The ulcerogenic effect of stored rice bran oil was reversed by cysteine which significantly reduced the ulcer incidence from 100% to 60% (P > 0.005) and the numbers of ulcers from 26 (six to 70) to one (zero to four) (P > 0.001). 3. Fresh rice bran significantly reduced the numbers of ulcers from six (one to ten) to one (one to four) (P > 0.05). Similarly, unmilled rice and freshly milled newly harvested rice was also shown to be protective in this model by significantly reducing the ulcer incidence from 87.5% to 50% and 0% respectively (P values > 0.025) and the numbers of ulcers from three (zero to 17) to one (zero to one) and zero (zero to zero) respectively (P values > 0.001). 4. These results could in part explain the geographical distribution of duodenal ulceration, where the incidence is high in all the rice eating areas of the world, and provide a plausible hypothesis to explain the mechanism of dietary ulcerogenesis.

scholarly journals Protective Effects of Defatted Sticky Rice Bran Extracts on the Early Stages of Hepatocarcinogenesis in Rats

Molecules ◽  
2019 ◽  
Vol 24 (11) ◽  
pp. 2142 ◽  
Author(s):  
Aphisit Dokkaew ◽  
Charatda Punvittayagul ◽  
Orapin Insuan ◽  
Pornngarm Limtrakul (Dejkriengkraikul) ◽  
Rawiwan Wongpoomchai
Keyword(s):  
Vitamin E ◽  
Phenolic Compounds ◽  
Rice Bran ◽  
Inhibitory Effect ◽  
Nuclear Antigen ◽  
Protective Effects ◽  
Glutathione S Transferase ◽  
Preneoplastic Lesions ◽  
Rice Bran Extract ◽  
Initiation Stage

Use of natural products is one strategy to lessen cancer incidence. Rice bran, especially from colored rice, contains high antioxidant activity. Cancer chemopreventive effects of hydrophilic purple rice bran extract (PRBE) and white rice bran extract (WRBE) on carcinogen-induced preneoplastic lesion formation in livers of rats were investigated. A 15-week administration of PRBE and WRBE did not induce hepatic glutathione S-transferase placental form (GST-P) positive foci formation as the biomarker of rat hepatocarcinogenesis. PRBE and WRBE at 500 mg/kg body weight significantly decreased number and size of GST-P positive foci in diethylnitrosamine (DEN)-initiated rats. The number of proliferating nuclear antigen positive hepatocytes were also reduced in preneoplastic lesions in both PRBE and WRBE fed DEN-treated rats. Notably, the inhibitory effect on GST-P positive foci formation induced by DEN during the initiation stage was found only in rats treated by PRBE for five weeks. Furthermore, PRBE attenuated the expression of proinflammatory cytokines involving genes including TNF-α, iNOS, and NF-κB. PBRE contained a higher number of anthocyanins and other phenolic compounds and vitamin E. PRBE might protect DEN-induced hepatocarcinogenesis in rats via attenuation of cellular inflammation and cell proliferation. Anthocyanins and other phenolic compounds, as well as vitamin E, might play a role in cancer chemopreventive activity in rice bran extract.

scholarly journals The Driselase-treated fraction of rice bran is a more effective dietary factor to improve hypertension, glucose and lipid metabolism in stroke-prone spontaneously hypertensive rats compared to ferulic acid

2007 ◽  
Vol 97 (1) ◽  
pp. 67-76 ◽  
Author(s):  
Ardiansyah ◽  
Hitoshi Shirakawa ◽  
Takuya Koseki ◽  
Katsumi Hashizume ◽  
Michio Komai
Keyword(s):  
Lipid Metabolism ◽  
Ferulic Acid ◽  
Rice Bran ◽  
Spontaneously Hypertensive Rats ◽  
Control Diet ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Glucose And Lipid Metabolism ◽  
The Metabolic Syndrome ◽  
Hepatic Triacylglycerol

The aim of this study is to investigate the effects of dietary supplementation with the Driselase-treated fraction (DF) of rice bran and ferulic acid (FA) on hypertension and glucose and lipid metabolism in stroke-prone spontaneously hypertensive rats (SHRSP). Male SHRSP at 4 weeks of age were divided into three groups, and for 8 weeks were fed (1) a control diet based on AIN-93M, (2) a DF of rice bran-supplemented diet at 60 g/kg and (3) an FA-supplemented diet at 0·01 g/kg. Means and standard errors were calculated and the data were tested by one-way ANOVA followed by a least significance difference test. The results showed that both the DF and FA diets significantly improved hypertension as well as glucose tolerance, plasma nitric oxide (NOx), urinary 8-hydroxy-2′-deoxyguanosine and other parameters. In particular, compared to the FA diet, the DF diet produced a significant improvement in urinary NOx, hepatic triacylglycerol and several mRNA expressions of metabolic parameters involved in glucose and lipid metabolisms. The results of the metabolic syndrome-related parameters obtained from this study suggest that the DF diet is more effective than the FA diet.

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