Anti-inflammatory activities of the products of supercritical fluid extraction from Litsea japonica fruit in RAW 264.7 cells

2016 ◽  
Vol 22 ◽  
pp. 44-51 ◽  
Author(s):  
Sang-Mok Song ◽  
Young-Min Ham ◽  
Yoeng-Jong Ko ◽  
Eun-Yi Ko ◽  
Dae-Ju Oh ◽  
...  
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Fluid Extraction ◽  
Litsea Japonica ◽  
Anti Inflammatory

scholarly journals Chemical Composition, Antioxidant, and Anti-Inflammatory Activity of Essential Oil from Omija (Schisandra chinensis (Turcz.) Baill.) Produced by Supercritical Fluid Extraction Using CO2

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1619
Author(s):  
Jae-Hoon Lee ◽  
Yun-Yeol Lee ◽  
Jangho Lee ◽  
Young-Jin Jang ◽  
Hae-Won Jang
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Inflammatory Activity ◽  
Composition Analysis ◽  
Raw 264.7 ◽  
Schisandra Chinensis ◽  
Fluid Extraction ◽  
Anti Inflammatory

Schisandra chinensis (Turcz.) Baill., which is known as omija in South Korea, is mainly cultivated in East Asia. The present study aimed to investigate the chemical composition of essential oil from the omija (OMEO) fruit obtained by supercritical fluid extraction using CO2 and to confirm the antioxidant and anti-inflammatory activity of OMEO using HaCaT human keratinocyte and RAW 264.7 murine macrophages. As a result of the chemical composition analysis of OMEO using gas chromatography-mass spectrometry, a total of 41 compounds were identified. The detailed analysis results are sesquiterpenoids (16), monoterpenoids (14), ketones (4), alcohols (3), aldehydes (2), acids (1), and aromatic hydrocarbons (1). OMEO significantly reduced the increased ROS levels in HaCaT keratinocytes induced by UV-B irradiation (p < 0.05). It was confirmed that 5 compounds (α-pinene, camphene, β-myrcene, 2-nonanone, and nerolidol) present in OMEO exhibited inhibitory activity on ROS production. Furthermore, OMEO showed excellent anti-inflammatory activity in RAW 264.7 macrophages induced by lipopolysaccharide. OMEO effectively inhibited NO production (p < 0.05) by suppressing the expression of the iNOS protein. Finally, OMEO was investigated for exhibition of anti-inflammatory activity by inhibiting the activation of NF-κB pathway. Taken together, OMEO could be used as a functional food ingredient with excellent antioxidant and anti-inflammatory activity.

scholarly journals Obtaining geranylgeraniol-rich oil by supercritical technology for the development of functional emulsion-filled gel

2018 ◽  
Author(s):  
Carla Daniela de O. Nascimento ◽  
Renata Vardanega ◽  
Eric Keven Silva ◽  
Maria Angela de Almeida Meireles
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
High Intensity ◽  
Seed Oil ◽  
Fluid Extraction ◽  
High Intensity Ultrasound ◽  
Oil Fraction ◽  
Anti Inflammatory

The goal of this study was the obtaining of annatto seed oil fraction rich in geranylgeraniol and tocotrienols by sequential supercritical fluid extraction and to use the geranylgeraniol-rich fraction to develop emulsion-filled gels with anti-inflammatory properties by high-intensity ultrasound.

Supercritical fluid extraction of grape seeds: extract chemical composition, antioxidant activity and inhibition of nitrite production in LPS-stimulated Raw 264.7 cells

2015 ◽  
Vol 6 (8) ◽  
pp. 2607-2613 ◽  
Author(s):  
Concepción Pérez ◽  
María Luisa Ruiz del Castillo ◽  
Carmen Gil ◽  
Gracia Patricia Blanch ◽  
Gema Flores
Keyword(s):  
Antioxidant Activity ◽  
Chemical Composition ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Grape Seeds ◽  
Nitrite Production ◽  
Medicinal Properties ◽  
By Products

Grape by-products are a rich source of bioactive compounds having broad medicinal properties, but are usually wasted from juice/wine processing industries.

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