Prevalence and trends of insulin resistance, impaired fasting glucose, and diabetes

2007 ◽  
Vol 21 (6) ◽  
pp. 363-370 ◽  
Author(s):  
George N. Ioannou ◽  
Chris L. Bryson ◽  
Edward J. Boyko
Keyword(s):  
Insulin Resistance ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose

scholarly journals Physical Activity, Measures of Obesity, and Cardiometabolic Risk: The Multi-Ethnic Study of Atherosclerosis (MESA)

2014 ◽  
Vol 11 (4) ◽  
pp. 831-837 ◽  
Author(s):  
Paul A. McAuley ◽  
Haiying Chen ◽  
Duck-chul Lee ◽  
Enrique Garcia Artero ◽  
David A. Bluemke ◽  
...  
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Waist Circumference ◽  
Impaired Fasting Glucose ◽  
Central Obesity ◽  
Cardiometabolic Risk ◽  
Fasting Glucose ◽  
Reference Group ◽  
Model Assessment ◽  
Ethnic Study

Background:The influence of higher physical activity on the relationship between adiposity and cardiometabolic risk is not completely understood.Methods:Between 2000–2002, data were collected on 6795 Multi-Ethnic Study of Atherosclerosis (MESA) participants. Self-reported intentional physical activity in the lowest quartile (0–105 MET-minutes/week) was categorized as inactive and the upper three quartiles (123–37,260 MET-minutes/week) as active. Associations of body mass index (BMI) and waist circumference categories, stratified by physical activity status (inactive or active) with cardiometabolic risk factors (dyslipidemia, hypertension, upper quartile of homeostasis model assessment of insulin resistance [HOMA-IR] for population, and impaired fasting glucose or diabetes) were assessed using logistic regression analysis adjusting for age, gender, race/ethnicity, and current smoking.Results:Among obese participants, those who were physically active had reduced odds of insulin resistance (47% lower; P < .001) and impaired fasting glucose/diabetes (23% lower; P = .04). These associations were weaker for central obesity. However, among participants with a normal waist circumference, those who were inactive were 63% more likely to have insulin resistance (OR [95% CI] 1.63 [1.24–2.15]) compared with the active reference group.Conclusions:Physical activity was inversely related to the cardiometabolic risk associated with obesity and central obesity.

Rosuvastatin treatment is associated with an increase in insulin resistance in hyperlipidaemic patients with impaired fasting glucose

2009 ◽  
Vol 63 (9) ◽  
pp. 1308-1313 ◽  
Author(s):  
M. S. Kostapanos ◽  
H. J. Milionis ◽  
A.-D. Agouridis ◽  
C. V. Rizos ◽  
M. S. Elisaf
Keyword(s):  
Insulin Resistance ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose

scholarly journals Association of Interleukin-6 and Myeloperoxidase with Insulin Resistance in Impaired Fasting Glucose Subjects

2016 ◽  
Vol 32 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Ashish Agarwal ◽  
Anupama Hegde ◽  
Charu Yadav ◽  
Afzal Ahmad ◽  
Poornima Ajay Manjrekar ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Impaired Fasting Glucose ◽  
Interleukin 6 ◽  
Fasting Glucose

scholarly journals Hypoglycemic Activity of Okra (Abelmoschus esculentus) in Participants with Impaired

2019 ◽  
Vol 7 (1) ◽  
pp. 626-635
Author(s):  
Czari Jo Lauren ADAP ◽  
CARLA RHOCEL T DIAZ ◽  
Paula Louise J. Victorino ◽  
Ma. Kristine HERNANDEZ MENDOZA ◽  
YANNA YVONNE CAAGBAY MACAYAN
Keyword(s):  
Insulin Resistance ◽  
Blood Glucose ◽  
Short Duration ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Abelmoschus Esculentus ◽  
Glucose Load ◽  
Experimental Phase ◽  
Control Phase ◽  
Glucose Levels

Introduction: Impaired fasting glucose (IFG) is characterized by a blood glucose level higher than normal but lower than that of diabetes level. Abelmoschus esculentus (okra) is an alternative hypoglycemic and antidiabetic plant due to its phytochemical constituents that regulate intestinal glucose absorption and prevents insulin resistance. This study determined the hypoglycemic activity of okra among IFG participants. Methodology: Subjects were random subjects with impaired fasting glucose results upon screening.  Quasi-experimental pre-test post-test was used where a standard glucose load was consumed in the control phase and powdered okra seed-peel mixed with the glucose load was consumed during the experimental phase. The blood sugar concentration was measured again every hour until three hours after consumption of the standard glucose load. In the experimental phase, the same group of participants was asked to consume 75 grams of glucose load with powdered okra peel that depends on their body weight (200 mg/kg of body mass). Fasting, 1 -hour, 2-hour and 3-hour glucose concentration were measured the same way it was done during the control phase. Results: Statistical analysis revealed that Abelmoschus esculentus has its hypoglycemic effect only during the first hour while data results for the 2nd and 3 rd hour are considered insignificant. The results proved that okra’s mechanism in lowering glucose levels is immediate yet of short duration. Discussion: Based on the data gathered, the researchers conclude that the powdered peel of Abelmoschus esculentus (okra) is effective in lowering the blood glucose levels of IFG individuals only during the first hour after the administration of oral glucose load. Abelmoschus esculentus may not be effective in lowering the blood glucose after the next hours due to the fact that its mechanism of action is immediate but of short duration. The researchers recommend future researches on the study of Abelmoschus esculentus using increased dosage of each participant and that the experiment should be performed at the same month.   Keywords: Abelmoschus esculentus, okra, impaired fasting glucose, diabetes, hypoglycaemia, insulin resistance

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