scholarly journals Association of Albuminuria With Intraglomerular Hydrostatic Pressure and Insulin Resistance in Subjects With Impaired Fasting Glucose and/or Impaired Glucose Tolerance

Diabetes Care ◽  
2018 ◽  
Vol 41 (11) ◽  
pp. 2414-2420 ◽  
Author(s):  
Akihiro Tsuda ◽  
Eiji Ishimura ◽  
Hideki Uedono ◽  
Akinobu Ochi ◽  
Shinya Nakatani ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Hydrostatic Pressure ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose

scholarly journals The positive association between serum uric acid, impaired fasting glucose, impaired glucose tolerance, and diabetes mellitus in the ELSA-Brasil study

2021 ◽  
Vol 37 (9) ◽  
Author(s):  
Aline Isabel Rodrigues Galvão ◽  
Alline Maria R. Beleigoli ◽  
Pedro Guatimosim Vidigal ◽  
Bruce Bartholow Duncan ◽  
Maria Inês Schmidt ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Uric Acid ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Serum Uric Acid ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Newly Diagnosed ◽  
Glycemic Status

Abstract: There is a conflict in the literature regarding the association between serum uric acid (SUA) levels and glycemic status. Therefore, we evaluated the association between SUA level and glycemic status - impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus - and insulin resistance, in a large Brazilian study. This is a cross-sectional, observational study with 13,207 participants aged 35-74 years, at baseline (2008-2010) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). A multinomial regression analysis was performed to test the association between SUA and glycemic status (IFG, IGT, and newly diagnosed type 2 diabetes at the cohort baseline) after adjustments by age, sex, skin color, body mass index, physical activity, smoking, alcohol consumption, comorbidities, and medicines use. Logistic regression model was used to evaluate the association between SUA and insulin resistance by HOMA-IR. Stratified analyses by sex were performed. The mean age (standard deviation) was 51.4 (8.9) years, 55.2% of participants were women. There were 1,439 newly diagnosed diabetes. After all adjustments, higher SUA was associated with IFG, IGT, and diabetes, with odds ratio (OR) = 1.15 (95%CI: 1.06; 1.25), 1.23 (95%CI: 1.14; 1.33), and 1.37 (95%CI: 1.24; 1.51), respectively. There was association between SUA levels and insulin resistance with OR = 1.24 (95%CI: 1.13; 1.36). In analysis stratified by sex, higher SUA persisted independently associated with impaired glycemic status. Our results suggest that a higher SUA levels were significantly associated with glycemic status in a large Latin American population, mainly among women.

scholarly journals Differences in Insulin Resistance in Nondiabetic Subjects With Isolated Impaired Glucose Tolerance or Isolated Impaired Fasting Glucose

Diabetes ◽  
2004 ◽  
Vol 53 (6) ◽  
pp. 1549-1555 ◽  
Author(s):  
A. Festa ◽  
R. D'Agostino ◽  
A. J.G. Hanley ◽  
A. J. Karter ◽  
M. F. Saad ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose
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