Novel pH-sensitive zwitterionic poly(amino acid) derivatives for drug delivery

2011 ◽  
Vol 152 ◽  
pp. e93-e94 ◽  
Author(s):  
Xiaojuan Wang ◽  
Guolin Wu ◽  
Tao He ◽  
Yong Wang ◽  
Yinong Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Ph Sensitive ◽  
Amino Acid Derivatives

Amino acid derivatives of 5-ASA as novel prodrugs for intestinal drug delivery

1994 ◽  
Vol 39 (12) ◽  
pp. 2601-2606 ◽  
Author(s):  
Carlo Clerici ◽  
Giorgio Gentili ◽  
Enrico Boschetti ◽  
Carla Santucci ◽  
Aaron Garzon Aburbeh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Derivatives Of

Can self-assembled hydrogels composed of aromatic amino acid derivatives function as drug delivery carriers?

2017 ◽  
Vol 41 (1) ◽  
pp. 308-315 ◽  
Author(s):  
Priyanka Tiwari ◽  
Ramanathan Rajagopalan ◽  
Mohammad Moin ◽  
Rohit Soni ◽  
Piyush Trivedi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Aromatic Amino Acid ◽  
Amino Acid Derivatives ◽  
Self Assembled

This work reflects the efficient candidature of the hydrogelators and nanoparticles generated therefrom as excellent carriers for drug delivery.

Self-aggregates of oligoarginine-conjugated poly(amino acid) derivatives as a carrier for intracellular drug delivery

2005 ◽  
Vol 27 (14) ◽  
pp. 977-982 ◽  
Author(s):  
Seung Rim Yang ◽  
Seung Beom Kim ◽  
Cheol O. Joe ◽  
Jong-Duk Kim
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Intracellular Drug Delivery

scholarly journals Current Status of Amino Acid-Based Permeation Enhancers in Transdermal Drug Delivery

Membranes ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 343
Author(s):  
Rui Pereira ◽  
Sandra G. Silva ◽  
Marina Pinheiro ◽  
Salette Reis ◽  
M. Luísa do Vale
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Transdermal Drug Delivery ◽  
Barrier Properties ◽  
Structural Features ◽  
Current Status ◽  
Amino Acid Derivatives ◽  
Full Potential ◽  
Permeation Enhancers ◽  
Chemical Permeation Enhancers

Transdermal drug delivery (TDD) presents many advantages compared to other conventional routes of drug administration, yet its full potential has not been achieved. The administration of drugs through the skin is hampered by the natural barrier properties of the skin, which results in poor permeation of most drugs. Several methods have been developed to overcome this limitation. One of the approaches to increase drug permeation and thus to enable TDD for a wider range of drugs consists in the use of chemical permeation enhancers (CPEs), compounds that interact with skin to ultimately increase drug flux. Amino acid derivatives show great potential as permeation enhancers, as they exhibit high biodegradability and low toxicity. Here we present an overview of amino acid derivatives investigated so far as CPEs for the delivery of hydrophilic and lipophilic drugs across the skin, focusing on the structural features which promote their enhancement capacity.

Amino acid derivatives of UDCA as novel prodrugs for colon-specific drug delivery

2000 ◽  
Vol 118 (4) ◽  
pp. A517
Author(s):  
Carlo Clerici ◽  
Roberto Pellicciari ◽  
Kenneth Setchell ◽  
Nancy O'Connel ◽  
Giorgio Gentili ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Specific Drug ◽  
Colon Specific Drug Delivery ◽  
Derivatives Of

Three Amino Acid Derivatives of Valproic Acid: Design, Synthesis, Theoretical and Experimental Evaluation as Anticancer Agents

2014 ◽  
Vol 14 (7) ◽  
pp. 984-993 ◽  
Author(s):  
Gabriela Luna-Palencia ◽  
Federico Martinez-Ramos ◽  
Ismael Vasquez-Moctezuma ◽  
Manuel Fragoso-Vazquez ◽  
Jessica Mendieta-Wejebe ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Amino Acid ◽  
Anticancer Agents ◽  
Experimental Evaluation ◽  
Amino Acid Derivatives ◽  
Design Synthesis ◽  
Derivatives Of

scholarly journals In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

2019 ◽  
Vol 34 (1) ◽  
pp. 1247-1258 ◽  
Author(s):  
Asmaa F. Kassem ◽  
Gaber O. Moustafa ◽  
Eman S. Nossier ◽  
Hemat S. Khalaf ◽  
Marwa M. Mounier ◽  
...  
Keyword(s):  
Amino Acid ◽  
Molecular Modelling ◽  
Amino Acid Derivatives ◽  
Modelling Study

pH-sensitive polymers for drug delivery

2012 ◽  
Vol 20 (3) ◽  
pp. 224-233 ◽  
Author(s):  
Kang Moo Huh ◽  
Han Chang Kang ◽  
Young Ju Lee ◽  
You Han Bae
Keyword(s):  
Drug Delivery ◽  
Ph Sensitive
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