Erratum to “Folate-conjugated methoxy poly(ethylene glycol)/poly(ε-caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery” [Journal of Controlled Release 109 (2005) 158–168]

2006 ◽  
Vol 112 (1) ◽  
pp. 145-146 ◽  
Author(s):  
Eun Kyoung Park ◽  
So Yeon Kim ◽  
Sang Bong Lee ◽  
Young Moo Lee
2017 ◽  
Vol 18 (9) ◽  
pp. 2711-2722 ◽  
Author(s):  
Lin Xiao ◽  
Lixia Huang ◽  
Firmin Moingeon ◽  
Mario Gauthier ◽  
Guang Yang

Polymers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1124 ◽  
Author(s):  
Shuang Yang ◽  
Feng Ding ◽  
Zhiliang Gao ◽  
Jianman Guo ◽  
Jiwei Cui ◽  
...  

To reduce nonspecific interactions and circumvent biological barriers, low-fouling material of poly(ethylene glycol) (PEG) is most used for the modification of drug nanocarriers. Herein, we report the fabrication of PEG capsules via the free-radical polymerization of linear PEG or 8-arm-PEG using an emulsion templating method for targeted drug delivery. Doxorubicin (DOX) could be loaded in capsules via electrostatic interactions. The obtained capsules composed of 8-arm-PEG result in a lower cell association (2.2%) compared to those composed of linear PEG (7.3%) and, therefore, demonstrate the stealth property. The functionalization of cyclic peptides containing Arg-Gly-Asp (cRGD) on PEG capsules induce high cell targeting to U87 MG cells. A cell cytotoxicity assay demonstrates the biocompatibility of PEG capsules and high drug delivery efficacy of the targeted capsules. The reported capsules with the stealth and targeting property provide a potential platform for improved drug delivery.


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