Clinical evaluations of autologous fibrin glue and polyglycolic acid sheets as oral surgical wound coverings after partial glossectomy

2016 ◽  
Vol 44 (8) ◽  
pp. 964-968 ◽  
Author(s):  
Atsumu Kouketsu ◽  
Shinnosuke Nogami ◽  
Minami Fujiwara ◽  
Shiro Mori ◽  
Kensuke Yamauchi ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Surgical Wound ◽  
Clinical Evaluations ◽  
Autologous Fibrin Glue ◽  
Partial Glossectomy

Clinical evaluations of complete autologous fibrin glue, produced by the CryoSeal ® FS system, and polyglycolic acid sheets as wound coverings after oral surgery

2017 ◽  
Vol 45 (9) ◽  
pp. 1458-1463 ◽  
Author(s):  
Atsumu Kouketsu ◽  
Shinnosuke Nogami ◽  
Minami Yamada-Fujiwara ◽  
Hirokazu Nagai ◽  
Kensuke Yamauchi ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Oral Surgery ◽  
Polyglycolic Acid ◽  
Clinical Evaluations ◽  
Autologous Fibrin Glue

scholarly journals Application of polyglycolic acid sheet and fibrin glue spray for partial glossectomy: Comparison with artificial dermis

2011 ◽  
Vol 57 (7) ◽  
pp. 394-400 ◽  
Author(s):  
Junichiro TAKEUCHI ◽  
Masahiro UMEDA ◽  
Maho MURATA ◽  
Yasumasa KAKEI ◽  
Akira KIMOTO ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Artificial Dermis ◽  
Partial Glossectomy

Usefulness of Fibrin Glue and Polyglycolic Acid Sheet following Partial Glossectomy in the Elderly

2016 ◽  
Vol 145 (0) ◽  
pp. 74-74
Author(s):  
Takao Makise ◽  
Junichiro Ohori ◽  
Keiichi Miyashita ◽  
Hiroyuki Iuchi ◽  
Yuichi Kurono
Keyword(s):  
Fibrin Glue ◽  
The Elderly ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Partial Glossectomy

Clinical Evaluation of Application of Polyglycolic Acid Sheet and Fibrin Glue Spray for Partial Glossectomy

2013 ◽  
Vol 71 (2) ◽  
pp. e126-e131 ◽  
Author(s):  
Junichiro Takeuchi ◽  
Hiroaki Suzuki ◽  
Maho Murata ◽  
Yasumasa Kakei ◽  
Shinshou Ri ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Clinical Evaluation ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Partial Glossectomy

scholarly journals Utility of autologous fibrin glue and polyglycolic acid sheet for preventing delayed bleeding associated with antithrombotic therapy after gastric ESD

2019 ◽  
Vol 07 (11) ◽  
pp. E1542-E1548
Author(s):  
Daisuke Kikuchi ◽  
Toshiro Iizuka ◽  
Shigeyoshi Makino ◽  
Junnosuke Hayasaka ◽  
Hiroyuki Odagiri ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Antithrombotic Therapy ◽  
Polyglycolic Acid ◽  
Conventional Group ◽  
Serious Adverse Events ◽  
Bleeding Rate ◽  
Allogeneic Transfusion ◽  
Delayed Bleeding ◽  
Autologous Fibrin Glue ◽  
Adjusted Logistic Regression

Abstract Background and study aims Delayed bleeding is one of the most serious adverse events of gastric endoscopic submucosal dissection (ESD), especially in patients taking antithrombotic therapy. This study aimed to evaluate the utility and safety of a shielding method with autologous fibrin glue and polyglycolic acid (PGA) sheets for patients undergoing gastric ESD who are receiving antithrombotic therapy. Patients and methods One hundred twenty-three patients who were treated with gastric ESD while receiving antithrombotic therapy between December 2014 and September 2017 were enrolled in this study. Patients who received the shielding method were classified into the shielding group. Others were classified into the conventional group. Various clinico-pathological factors were retrospectively compared between the two groups. Results The shielding group consisted of 38 patients, and the conventional group consisted of the remaining 85 patients. In the shielding group, the rate of continuation of antithrombotic therapy was significantly higher (68.4 % vs 41.2 %). Incidence of delayed bleeding was lower in the shielding group (2.6 %, 1/38) than in the conventional group (14.1 %, 12/85). In the propensity score-adjusted logistic regression analysis, the delayed bleeding rate in the shielding group tended to be lower than in the conventional group (P = 0.070). Allogeneic transfusion was performed in eight patients (8/85, 9.4 %) in the conventional group and none in the shielding group (P = 0.047). No adverse event associated with endoscopic shielding were observed in the shielding group. Conclusions This study suggests that a shielding method with autologous fibrin glue and PGA sheet effectively prevents delayed bleeding after gastric ESD in patients receiving antithrombotic therapy.

Usefulness of Fibrin Glue and Polyglycolic Acid Sheet following Partial Glossectomy in the Elderly

2015 ◽  
Vol 108 (9) ◽  
pp. 709-712
Author(s):  
Takao Makise ◽  
Junichiro Ohori ◽  
Keiichi Miyashita ◽  
Hiroyuki Iuchi ◽  
Yuichi Kurono
Keyword(s):  
Fibrin Glue ◽  
The Elderly ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Partial Glossectomy

scholarly journals Feasibility of Autologous Fibrin Glue and Polyglycolic Acid Sheets to Prevent Delayed Bleeding after Endoscopic Submucosal Dissection of Gastric Neoplasms in Patients Receiving Antithrombotic Therapy

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Daisuke Kikuchi ◽  
Toshiro Iizuka ◽  
Kosuke Nomura ◽  
Yasutaka Kuribayashi ◽  
Masami Tanaka ◽  
...  
Keyword(s):  
Adverse Events ◽  
Endoscopic Submucosal Dissection ◽  
Fibrin Glue ◽  
Antithrombotic Therapy ◽  
Polyglycolic Acid ◽  
Safety Measure ◽  
Gastric Neoplasms ◽  
Delayed Bleeding ◽  
Submucosal Dissection ◽  
Autologous Fibrin Glue

Background/Aims. Delayed bleeding is one of the most serious complications following gastric endoscopic submucosal dissection (ESD) under antithrombotic therapy. As a safety measure, for patients receiving antithrombotic therapy, we covered the ESD ulcer with autologous fibrin glue (prepared using autologous blood) alone or with polyglycolic acid (PGA) sheets. Methods. From July 2014 to November 2015, 20 patients with gastric neoplasms who were receiving antithrombotic therapy were enrolled in this study. After ESD, the ESD ulcers were covered with autologous fibrin glue alone or with PGA sheets. We prospectively evaluated the feasibility of this safety measure. Results. In total, 22 lesions in 20 patients were resected en bloc by ESD. The mean specimen size and tumor size were 31.5 ± 9.5 mm and 14.0 ± 8.8 mm, respectively. There were no cases of delayed bleeding or adverse events in this study. Attachment of autologous fibrin glue was observed in 81.8% (18/22) and 68.2% (15/22) of lesions at endoscopy performed 1 day and 7 days after ESD, respectively. Conclusion. No patient in this study had delayed bleeding or adverse events. This suggests that this measure may facilitate the safety of gastric ESD in patients receiving antithrombotic therapy. This trial is registered with UMIN000019386.

Wound healing effect of autologous fibrin glue and polyglycolic acid sheets in a rat back skin defect model

2021 ◽  
pp. 103144
Author(s):  
Atsumu Kouketsu ◽  
Yoshinaka Shimizu ◽  
Shinnosuke Nogami ◽  
Minami Yamada-Fujiwara ◽  
Hirokazu Nagai ◽  
...  
Keyword(s):  
Wound Healing ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Skin Defect ◽  
Defect Model ◽  
Healing Effect ◽  
Autologous Fibrin Glue ◽  
Wound Healing Effect
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