scholarly journals Effect of self-setting α-tricalcium phosphate between segments for bone healing and hypoaesthesia in lower lip after sagittal split ramus osteotomy

2012 ◽  
Vol 40 (4) ◽  
pp. e119-e124 ◽  
Author(s):  
Koichiro Ueki ◽  
Katsuhiko Okabe ◽  
Kohei Marukawa ◽  
Aya Mukozawa ◽  
Akinori Moroi ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Sagittal Split Ramus Osteotomy ◽  
Lower Lip

scholarly journals Bone Healing Improvements Using Hyaluronic Acid and Hydroxyapatite/Beta-Tricalcium Phosphate in Combination: An Animal Study

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Yen-Lan Chang ◽  
Yi-June Lo ◽  
Sheng-Wei Feng ◽  
Yu-Chih Huang ◽  
Hsin-Yuan Tsai ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Control Sample ◽  
Volume Density ◽  
Parietal Bone ◽  
Control Group ◽  
Calvarial Bone ◽  
Handling Characteristics ◽  
Beta Tricalcium Phosphate ◽  
Aqueous Binder

The purpose of this study was to investigate whether the use of HLA as an aqueous binder of hydroxyapatite/beta-tricalcium phosphate (HA-βTCP) particles can reduce the amount of bone graft needed and increase ease of handling in clinical situations. In this study, HA/βTCP was loaded in commercially available crosslinking HLA to form a novel HLA/HA-βTCP composite. Six New Zealand White rabbits (3.0–3.6 kg) were used as test subjects. Four 6 mm defects were prepared in the parietal bone. The defects were filled with the HLA/HA-βTCP composite as well as HA-βTCP particle alone. New bone formation was analyzed by micro-CT and histomorphometry. Our results indicated that even when the HA-βTCP particle numbers were reduced, the regenerative effect on bone remained when the HLA existed. The bone volume density (BV/TV ratio) of HLA/HA-βTCP samples was 1.7 times larger than that of the control sample at week 2. The new bone increasing ratio (NBIR) of HLA/HA-βTCP samples was 1.78 times higher than the control group at week 2. In conclusion, HA-βTCP powder with HLA contributed to bone healing in rabbit calvarial bone defects. The addition of HLA to bone grafts not only promoted osteoconduction but also improved handling characteristics in clinical situations.

scholarly journals Histopathological evaluation of polycaprolactone nanocomposite compared with tricalcium phosphate in bone healing

2018 ◽  
Vol 62 (3) ◽  
pp. 385-394 ◽  
Author(s):  
Hadi Eftekhari ◽  
Alireza Jahandideh ◽  
Ahmad Asghari ◽  
Abolfazl Akbarzadeh ◽  
Saeed Hesaraki
Keyword(s):  
Bone Tissue ◽  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Healing Process ◽  
Control Group ◽  
Time Intervals ◽  
Positive Effects ◽  
Bone Scaffolds ◽  
Modern Engineering ◽  
And Control

AbstractIntroductionIn recent years, the use of bone scaffolds as bone tissue substitutes, especially the use of such as hydroxyapatite and tricalcium phosphate, has been very popular. Today, the use of modern engineering techniques and advances in nanotechnology have expanded the use of nanomaterials as bone scaffolds for bone tissue applications.Material and MethodsThis study was performed on 60 adult male New Zealand rabbits divided into four experimental groups: the control group without any treatment, the second group receiving hydroxyapatite, the third group treated with β-tricalcium phosphate, and the fourth group receiving nanocomposite polycaprolactone (PCL) scaffold. In a surgical procedure, a defect 6 mm in diameter was made in a hind limb femur. Four indexes were used to assess histopathology, which were union index, spongiosa index, cortex index, and bone marrow.ResultsThe results showed that nanocomposite PCL and control groups always had the respective highest and lowest values among all the groups at all time intervals. The histopathological assessment demonstrated that the quantity of newly formed lamellar bone in the nanocomposite PCL group was higher than in other groups.ConclusionAll these data suggest that PCL had positive effects on the bone healing process, which could have great potential in tissue engineering and clinical applications.

Mandibular bone healing after advancement or setback surgery using sagittal split ramus osteotomy

2018 ◽  
Vol 46 (9) ◽  
pp. 1500-1503 ◽  
Author(s):  
Koichiro Ueki ◽  
Akinori Moroi ◽  
Takamitsu Tsutsui ◽  
Asami Hotta ◽  
Ryota Hiraide ◽  
...  
Keyword(s):  
Bone Healing ◽  
Sagittal Split Ramus Osteotomy ◽  
Mandibular Bone

scholarly journals Bone healing of distal radius nonunion treated with bridge plating with bone graft substitutes in combination with systemic romosozumab administration: A case report

2021 ◽  
Vol 32 (2) ◽  
pp. 526-530
Author(s):  
Takuya Uemura ◽  
Koichi Yano ◽  
Kiyohito Takamatsu ◽  
Yusuke Miyashima ◽  
Hiroyuki Yasuda ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Bone Formation ◽  
Bone Graft ◽  
Distal Radius ◽  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Bone Union ◽  
Heavy Smoker ◽  
Bone Graft Substitutes ◽  
Bridge Plating

Romosozumab is a humanized, anti-sclerostin monoclonal antibody used to treat osteoporosis, which increases bone formation and decreases bone resorption. It enhances fracture healing and systemic romosozumab administration may have therapeutic potentials for accelerating bone healing of even nonunion. Herein, a 61-year-old heavy smoker male with distal radius nonunion who achieved successful bone union by combination therapy of romosozumab and spanning distraction plate fixation with bone graft substitutes was presented. Through the dorsal approach, atrophic comminuted nonunion of the distal radius was sufficiently debrided. Reduction of the distal radius was performed using indirect ligamentotaxis, and a 14-hole locking plate was fixed from the third metacarpal to the radial shaft. A beta (β) tricalcium phosphate block was mainly packed into the substantial metaphyseal bone defect with additional bone graft from the resected ulnar head. Postoperatively, systemic administration of monthly romosozumab was continued for six months. Complete bone union was achieved 20 weeks postoperatively and the plate was, then, removed. Wrist extension and flexion improved to 75o and 55o, respectively, without pain, and grip strength increased 52 weeks postoperatively from 5.5 kg to 22.4 kg. During romosozumab treatment, bone formation marker levels increased rapidly and finally returned to baseline, and bone resorption marker levels remained low. In conclusion, combination of systemic romosozumab administration and grafting β-tricalcium phosphate with bridge plating provides an effective treatment option for difficult cases of comminuted distal radius nonunion with risk factors such as smoking, diabetes, and fragility.

scholarly journals Differences in the Buccal Bone Marrow Distance of ≤0.8 mm in the Mandible of Patients Undergoing Sagittal Split Ramus Osteotomy among the Different Skeletal Patterns: A Retrospective Study

2021 ◽  
Vol 10 (23) ◽  
pp. 5644
Author(s):  
Yu-Chuan Tseng ◽  
Shih-Wei Liang ◽  
Szu-Ting Chou ◽  
Shih-Chieh Chen ◽  
Chin-Yun Pan ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Class Ii ◽  
B Value ◽  
Class I ◽  
Occurrence Rate ◽  
Class Iii ◽  
Sagittal Split Ramus Osteotomy ◽  
Lower Lip ◽  
B Values ◽  
Significant Difference

This study investigated the relationship between the thickness of the ramus and skeletal patterns using cone-beam computed tomography (CBCT) for sagittal split ramus osteotomy. Ninety participants were categorized into three skeletal patterns (Class I, Class II, and Class III). The first vertical slice (slice 0) was observed in the intact mandibular canal, and then moved forward to 40 mm (slice 21) with a 2 mm interval. The thickness of buccal bone marrow (B value) was measured. A B value of ≤0.8 mm was considered to be the major risk factor causing the occurrence of postoperative lower lip paresthesia. There were 461 sides with a B value of ≤0.8 mm. There was a significant difference in the skeletal patterns [Class III (198 sides: 15.7%) > Class I (159 sides: 12.6%) > Class II (104 sides: 8.3%)]. Class II participants had significantly larger B values (2.14 to 3.76 mm) and a lower occurrence rate (≤0.8 mm) than those of Class III participants (1.5 to 3 mm) in front of the mandibular foramen (from 6 mm to 20 mm). Class III participants had significantly shorter buccal bone marrow distance and a higher occurrence rate of B values (≤0.8 mm) than Class II.

scholarly journals Alteration of clot architecture using bone substitute biomaterials (beta-tricalcium phosphate) significantly delays the early bone healing process

2018 ◽  
Vol 6 (48) ◽  
pp. 8204-8213 ◽  
Author(s):  
Xin Wang ◽  
Yan Luo ◽  
Yan Yang ◽  
Baoyu Zheng ◽  
Fuhua Yan ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Bone Substitute ◽  
Blood Clot ◽  
Healing Process ◽  
The Body ◽  
Beta Tricalcium Phosphate ◽  
Bone Healing Process

When a bone substitute biomaterial is implanted into the body, the material's surface comes into contact with circulating blood, which results in the formation of a peri-implant hematoma or blood clot.

Sign in / Sign up

Export Citation Format

Share Document