scholarly journals Collision-activated dissociation, infrared multiphoton dissociation, and electron capture dissociation of the Bacillus anthracis siderophore petrobactin and its metal ion complexes

2007 ◽  
Vol 18 (5) ◽  
pp. 842-849 ◽  
Author(s):  
Haichuan Liu ◽  
Kristina Håkansson ◽  
Jung Yeop Lee ◽  
David H. Sherman
Keyword(s):  
Bacillus Anthracis ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Metal Ion ◽  
Infrared Multiphoton Dissociation ◽  
Metal Ion Complexes ◽  
Multiphoton Dissociation

scholarly journals Electron Capture Dissociation, Electron Detachment Dissociation and Infrared Multiphoton Dissociation of Sucrose Octasulfate

2009 ◽  
Vol 15 (2) ◽  
pp. 275-281 ◽  
Author(s):  
Jeremy J. Wolff ◽  
Tatiana N. Laremore ◽  
Franklin E. Leach ◽  
Robert J. Linhardt ◽  
I. Jonathan Amster
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Vibrational Excitation ◽  
Infrared Multiphoton Dissociation ◽  
Electron Detachment Dissociation ◽  
Electron Detachment ◽  
Sucrose Octasulfate ◽  
Product Ions ◽  
Multiphoton Dissociation

The structural analysis of sulfated carbohydrates such as glycosaminoglycans (GAGs) has been a long-standing challenge for the field of mass spectrometry. The dissociation of sulfated carbohydrates by collisionally-activated dissociation (CAD) or infrared multiphoton dissociation (IRMPD), which activate ions via vibrational excitation, typically result in few cleavages and abundant SO3 loss for highly sulfated GAGs such as heparin and heparan sulfate, hampering efforts to determine sites of modification. The recent application of electron activation techniques, specifically electron capture dissociation (ECD) and electron detachment dissociation (EDD), provides a marked improvement for the mass spectrometry characterization of GAGs. In this work, we compare ECD, EDD and IRMPD for the dissociation of the highly sulfated carbohydrate sucrose octasulfate (SOS). Both positive and negative multiply-charged ions are investigated. ECD, EDD and IRMPD of SOS produce abundant and reproducible fragmentation. The product ions produced by ECD are quite different than those produced by IRMPD of SOS positive ions, suggesting different dissociation mechanisms as a result of electronic versus vibrational excitation. The product ions produced by EDD and IRMPD of SOS negative ions also differ from each other. Evidence for SO3 rearrangement exists in the negative ion IRMPD data, complicating the assignment of product ions.

Dissociation of trivalent metal ion (Al3+, Ga3+, In3+and Rh3+)-peptide complexes under electron capture dissociation conditions

2016 ◽  
Vol 30 (6) ◽  
pp. 705-710 ◽  
Author(s):  
Xiangfeng Chen ◽  
Guoqiang Liu ◽  
Y. L. Elaine Wong ◽  
Liulin Deng ◽  
Ze Wang ◽  
...  
Keyword(s):  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Metal Ion ◽  
Trivalent Metal ◽  
Peptide Complexes

Combined Electron Capture and Infrared Multiphoton Dissociation for Multistage MS/MS in a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

2003 ◽  
Vol 75 (13) ◽  
pp. 3256-3262 ◽  
Author(s):  
Kristina Håkansson ◽  
Michael J. Chalmers ◽  
John P. Quinn ◽  
Melinda A. McFarland ◽  
Christopher L. Hendrickson ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Electron Capture ◽  
Mass Spectrometer ◽  
Cyclotron Resonance ◽  
Infrared Multiphoton Dissociation ◽  
Ion Cyclotron Resonance ◽  
Ion Cyclotron ◽  
Multiphoton Dissociation
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