Physical Frailty, Multimorbidity, and All-Cause Mortality in an Older Population From Southern Italy: Results from the Salus in Apulia Study

2021 ◽  
Vol 22 (3) ◽  
pp. 598-605
Author(s):  
Fabio Castellana ◽  
Luisa Lampignano ◽  
Ilaria Bortone ◽  
Roberta Zupo ◽  
Madia Lozupone ◽  
...  
Keyword(s):  
Southern Italy ◽  
Physical Frailty ◽  
Older Population ◽  
All Cause Mortality

Physical and Cognitive Profiles in Motor Cognitive Risk Syndrome in an Older Population From Southern Italy

2021 ◽  
Author(s):  
Ilaria Bortone ◽  
Chiara Griseta ◽  
Petronilla Battista ◽  
Fabio Castellana ◽  
Luisa Lampignano ◽  
...  
Keyword(s):  
Southern Italy ◽  
Cognitive Profiles ◽  
Older Population ◽  
Cognitive Risk

Clinical and laboratory predictors of all-cause mortality in older population

2007 ◽  
Vol 45 (3) ◽  
pp. 327-334 ◽  
Author(s):  
Tzuo-Yun Lan ◽  
Herng-Chia Chiu ◽  
Hsing-Yi Chang ◽  
Wen-Chiung Chang ◽  
Hui-Yang Chen ◽  
...  
Keyword(s):  
Older Population ◽  
All Cause Mortality

scholarly journals Cognitive Frailty and Its Long-Term Effect on Depression in an Older Population in Korea

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 442-442
Author(s):  
Yoonjung Ji ◽  
TaeWha Lee ◽  
Eunkyung Kim
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Group Analysis ◽  
Secondary Analysis ◽  
Epidemiological Studies ◽  
Physical Frailty ◽  
Older Population ◽  
Cognitive Frailty ◽  
The Relationship

Abstract Cognitive frailty is a condition where physical frailty and mild cognitive impairment (MCI) co-exist without dementia. It occurs in 1.8%-8.9% of the general older population, and older people with depression have a higher risk of frailty. However, the relationship between cognitive frailty and depression is still unclear. This study aimed to determine the relationship between cognitive frailty and depression of older adults by time using comparative group analysis. A secondary analysis was conducted using the Korean Longitudinal Study of Aging (KLoSA) dataset from 2010 to 2018. A sample was 981 older adults who were 65 years old and without dementia over residing in the community. Cognitive frailty was defined as having a mini-mental state examination score of 18-23 and 3 or more of the Fried frailty indexes. Generalized Estimating Equation model and chi-square test were employed. Of the 981 subjects, the cognitive frailty(CF) was 28.5%, followed by robust (37.7%), physical frailty (PF, 29.4%), mild cognitive impairment (MCI, 4.4%) at baseline. The group differences on depression measured by the Center for Epidemiological Studies Depression (CESD) were statistically significant in the PF (F=4.70, p<.001) and the CF (F=4.95, p<.001) group compared to the robust group. The time difference effect (F=.09, p=.05) and a group-by-time interaction effect were observed (p<.001). This study confirmed that cognitive frailty is strongly associated with depression. Effective approaches to managing psychological wellbeing, including dementia, are essential for older adults with cognitive frailty.

scholarly journals Age-Related Central Auditory Processing Disorder, MCI, and Dementia in an Older Population of Southern Italy

2020 ◽  
Vol 163 (2) ◽  
pp. 348-355 ◽  
Author(s):  
Rodolfo Sardone ◽  
Petronilla Battista ◽  
Rossella Donghia ◽  
Madia Lozupone ◽  
Rosanna Tortelli ◽  
...  
Keyword(s):  
Auditory Processing ◽  
Odds Ratio ◽  
Southern Italy ◽  
Population Based ◽  
Auditory Processing Disorder ◽  
Central Auditory Processing ◽  
Central Auditory Processing Disorder ◽  
Older Population ◽  
Cross Sectional ◽  
Age Related

Objective We explored the associations of age-related central auditory processing disorder (CAPD) with mild cognitive impairment (MCI) and dementia in an older population-based cohort in Apulia, Southern Italy (GreatAGE Study). Study Design Cross-sectional data from a population-based study. Setting Castellana Grotte, Bari, Italy. Subjects and Methods Between 2013 and 2018, MCI, dementia, age-related CAPD (no disabling hearing loss and <50% score on the SSI-ICM test [Synthetic Sentence Identification–Ipsilateral Competing Message]), neurologic and neuropsychological examinations, and serum metabolic biomarkers assays were investigated on 1647 healthy volunteers aged >65 years. Results The prevalences of age-related CAPD, MCI, and dementia were 14.15%, 15.79%, and 3.58%, respectively. Among the subjects with MCI and dementia, 19.61% and 42.37% had age-related CAPD. In the regressive models, age-related CAPD was associated with MCI (odds ratio, 1.50; 95% CI, 1.01-2.21) and dementia (odds ratio, 2.23; 95% CI, 1.12-4.42). Global cognition scores were positively associated with increasing SSI-ICM scores in linear models. All models were adjusted for demographics and metabolic serum biomarkers. Conclusion The tight association of age-related CAPD with MCI and dementia suggests the involvement of central auditory pathways in neurodegeneration, but it is not clear which is the real direction of this association. However, CAPD is a possible diagnostic marker of cognitive dysfunction in older patients.

scholarly journals Effect of social support on all-cause mortality risk in physical frailty Japanese elderly

2020 ◽  
Vol 84 (0) ◽  
pp. PR-004-PR-004
Author(s):  
Chikako Tange ◽  
Yukiko Nishita ◽  
Makiko Tomida ◽  
Takeshi Nakagawa ◽  
Rei Otsuka ◽  
...  
Keyword(s):  
Social Support ◽  
Mortality Risk ◽  
Physical Frailty ◽  
All Cause Mortality ◽  
Japanese Elderly

scholarly journals Associations of Grip Strength and Change in Grip Strength With All-Cause and Cardiovascular Mortality in a European Older Population

2018 ◽  
Vol 12 ◽  
pp. 117954681877189 ◽  
Author(s):  
Orawan Prasitsiriphon ◽  
Wiraporn Pothisiri
Keyword(s):  
Grip Strength ◽  
Cardiovascular Mortality ◽  
Older Persons ◽  
Information Criterion ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Older Population ◽  
Strength Change ◽  
Cox Proportional Hazard ◽  
All Cause Mortality

Objective: (1) To examine the associations between 3 measures of grip strength: static grip strength, change in grip strength, and the combination of grip strength and its change, with all-cause and cardiovascular mortality, and (2) to determine which measure is the most powerful predictor of all-cause and cardiovascular mortality among the European older population. Method: Data come from the first 4 waves of the Survey of Health, Ageing and Retirement in Europe (SHARE). A Cox proportional hazard model and a competing risk regression model were used to assess the associations. To determine the best predictor, Akaike information criterion was applied. Results: Grip strength and the combination of grip strength and its change were associated with all-cause and cardiovascular mortality. Change in grip strength was correlated with only all-cause mortality. Among the 3 measures, the static measure of grip strength was the best predictor of cardiovascular mortality whereas the combined measure is that of all-cause mortality. Discussion: Grip strength is a significant indicator of all-cause and cardiovascular mortality. The combination of grip strength and its change can be used to increase the accuracy for prediction of all-cause mortality among older persons.

Progression of Physical Frailty and the Risk of All‐Cause Mortality: Is There a Point of No Return?

2020 ◽  
Author(s):  
Qian‐Li Xue ◽  
Karen Bandeen‐Roche ◽  
Jing Tian ◽  
Judith D. Kasper ◽  
Linda P. Fried
Keyword(s):  
Physical Frailty ◽  
All Cause Mortality ◽  
Point Of No Return
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